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Tag: "dramatically" at biology news

Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

...rs found that after HIV docks onto a host cell, it dramatically lowers the energy required for a cell membrane to ...dly infections. “We found that HIV fusion peptide dramatically decreases the amount of energy needed to bend a cell-like membrane,” said Stephanie Tristram-Nagle, ...

U-M researchers discover gene switched off in cancer can be turned on

... to this disease today. Targeted therapies have dramatically improved cancer care in recent years, because they thwart the specific genes which drive the development and progress of cancers. They typically have few toxic side effects, unlike traditional chemotherapy, making them more tolerable as a long-term t...

Penn researchers link cell's protein recycling systems

...at making the lysosomal system more or less active dramatically influenced the severity of neurodegeneration. “We found that whenever we knocked the lysosome system down, neurodegeneration always got worse,” says Taylor. “Then when we activated the autophagy system by feeding the flies a drug called rapamycin...

Herpes virus hijacks DNA repair process

...ge response. The virus's ability to replicate also dramatically decreased. Kinases are versatile proteins that sometimes play multiple roles. To ensure that enhanced viral replication wasn't linked to orf36's interactions with other molecules, researchers turned to mice lacking the genes for ATM and H2AX, the ...

Staphylococcus aureus hides out in cells

...lung cells, the bacteria’s gene expression profile dramatically changed: gene expression for bacterial metabolic functions and transport shut down, putting the bacteria in a dormant state. Simultaneously, production of toxins potentially lethal for the epithelial cells becomes strictly controlled to limit cellula...

Researchers develop buckyballs to fight allergy

... the buckyball enables it to bind to free radicals dramatically better than any anti-oxidant currently available, such as vitamin E. Free radicals are molecules that cause oxidative stress, which experts believe may be the basis of aging. “The immune system both protects us and causes harm, so we are always in...

Mice with a migraine show signs of brain damage

...raines. Even though the brain’s arteries expand dramatically and make a great deal more oxygen-rich blood available to meet the demand for energy, some parts of the brain still wind up experiencing severe oxygen shortage, or hypoxia. This causes parts of brain cells?sophisticated signaling structures to disint...

Global survey of lizards reveals greater abundance of animals on islands than on mainland ecosystems

...o biological invasions, which will likely increase dramatically with changing climate,?says Walter Jetz, an assistant professor of biological sciences at UCSD and a co-author of the study. “Climate change will drive animals to move to new places,?says Lauren Buckley, a postdoctoral fellow at the Santa Fe Insti...

US control strategies may make flu epidemics worse, UCLA study shows

...e and personality factors into epidemic models can dramatically change our understanding of why flu epidemics occur." said Vardavas. ...

Novel system developed to turn data into real-time, interactive 3-D images

... Kent State University will provide doctors with a dramatically improved ability to evaluate medical images that are commonly used. This patent-pending technology allows for interactive viewing of large image data sets from virtually any medical imaging device and has led to a licensing agreement with Northeast-O...

DNA-damage test could aid drug development

...ssing a compound's genetic toxicity that may prove dramatically cheaper than existing animal tests. This assay would allow genetic toxicity to be examined far earlier in the drug development process, making it much more efficient. Like the current FDA-approved test, the new test looks for DNA damage in red blood...

Rapid response was crucial to containing the 1918 flu pandemic

...s at NIAID. Despite the fact that these cities had dramatically different outcomes early on, all the cities in the survey ultimately experienced significant epidemics because, in the absence of an effective vaccine, the virus continued to spread or recurred as cities relaxed their restrictions. The second stud...

Gut research yields new anti-cancer approach

..."This is the first observation of a small molecule dramatically reducing levels of the proteins called tubulins, the building blocks of cancer cell skeletons," said Katherine L. Schaefer, Ph.D., a research assistant professor within the Department of Medicine, Gastroenterology and Hepatology Division, at the Univ...

Scientists identify molecular cause for one form of deafness

.... "We found the structure of the bundles changes dramatically when normal espin is replaced with espin mutants that cause deafness," said Gerard Wong, a professor of materials science and engineering, of physics, and of bioengineering at the University of Illinois at Urbana-Champaign. "The interior structure ...

New report: Explosive growth changes salmon industry

...t found that the rapid growth in farmed salmon has dramatically increased total salmon supply, changed the kinds of salmon products that are available, altered the timing of production and raised market quality standards. These changes have raised economic, environmental and trade questions. For example, how doe...

The penalty of having a sister -- why sibling sex matters for male saiga antelopes

...th weight for males and females of the species are dramatically different. The researchers' study of female saigas and their young also showed that they invest more in their pregnancy than any other hoofed mammal, with some mothers carrying young up to 38% of their own body weight. The research was ...

Nanotextured implant materials: blending in, not fighting back

...imply changing the surface texture of implants can dramatically change the way cells colonize a wide variety of materials. Two recent experiments have focused on the materials used in stents ?those springy little cylinders that hold open once-clogged arteries ?and artificial blood vessels. Currently only about ...

Brown cancer biologists identify major player in cell growth

...rupted, and the fibroblasts' ability to divide was dramatically reduced. At the same time, other genes known to restart cell division were unchanged. The team confirmed GABP's critical role in cell growth another way. Simply forcing dormant cells to make GABP, they found, was enough to rouse cells from their s...

Scientists find hormone activity explains adolescent mood swings

...or normally has very low expression, but increases dramatically at the onset of puberty in the part of the brain that regulates emotion. Paradoxically, THP reduced the inhibition produced by these alpha4-beta2-delta GABA-A receptors, increasing brain activity to produce a state of increased anxiety. Stress also i...

Newborn brains grow vision and movement regions first

... control vision and other sensory information grow dramatically in the first few months following birth, while the area that controls abstract thought experiences very little growth during the same period, University of North Carolina at Chapel Hill researchers have found. The researchers discovered that the bac...

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