Tag: "dosing" at biology news

Study suggests some drug resistance to influenza B medications

...enza A, an important concern is whether suboptimal dosing for these viruses will lead to increased selection of viruses with high-level resistance.? “Influenza viruses evolve rapidly and nimbly, which compels ongoing investigation of antiviral therapies that use alternative mechanisms of action and target...

UW launches study testing adult stem cells for heart damage repair

...are randomly selected to receive either one of two dosing levels of CD34+ stem cells, or placebo. Subjects will receive follow-up examinations for 12 months following the investigative procedure. "The initial results from Phase I of the trial were encouraging," Raval says. "Subjects reported feeling bet...

Researchers urge monitoring of bone health during chemotherapy

...er disease-free period than those getting standard dosing without G-CSF. "It's possible that women on G-CSF-supported chemotherapy could do even better if we paid more attention to skeletal health," says lead author Angela Hirbe, an M.D./Ph.D. student in Weilbaecher's lab. "Strengthening the skeleton wou...

Vaccination with embryonic stem cells prevents lung cancer in mice

...ancer (3-methylcholanthrene followed by repetitive dosing with butylated hydroxytoluene), ESCs resulted in 60% of mice remaining tumour free after 27 weeks and ESC + STO/GM-CSF resulted in 90% remaining tumour free. Importantly, tumours arising in vaccinated mice were, on average, about 80-90% smaller than...

New GI technologies improve internal organ visualization

...dministered propofol using the CAPS system and its dosing algorithm and safety shell--a control safeguard software program. Data was downloaded from the sedation device to a laptop computer to measure patient response throughout the procedure and adjust the sedation dosage accordingly. Patient responsiven...

Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy

...the safety of long-term use remain. "If issues of dosing and long-term safety can be resolved, our research suggests that poloxamer 188 could be a new therapeutic agent for preventing or limiting progressive damage to the hearts of patients with muscular dystrophy," Metzger says. ...

Newest HIV drugs should be used with FUZEON(R)

...tients not receiving FUZEON POWER Phase II TMC114 dosing trials Over 24 weeks in the combined TMC114 trials, almost double the proportion of patients who received FUZEON plus TMC114/r achieved a viral load below 50 copies/ml compared with patients not receiving FUZEON A remarkable 67% of the patients recei...

Prescription Drug Patches Gaining Ground, Tackling New Therapies

...table and that are capable of delivering sustained dosing of active compounds for several days in a smaller package. “The number of drug therapies being developed in patch form is expanding,?explains George Perros, Greystone Managing Director. “At the same time, improvements in patch esthetics and the succe...

Canada approves marijuana-based pain spray

...ef. The spray formulation allows for more flexible dosing than an oral tablet, well suited to the variable n... for self-administration, this allows for flexible dosing and puts the patient in control of their pain,?said Dr. Gordon. “This is very important since pain s...

Scientists Propose Sweeping Changes to Naming of Bird Neurosystems to Acknowledge Their True Brainpower

...mbinations, non-steroidal analgesics, or as needed dosing with short-acting opioids. Fentanyl is currently a Schedule II controlled substance, which is the highest level of control for drugs with a recognized medical use. As a controlled substance in Schedule II of the Controlled Substances Act (CSA), Fent...

FDA Clears the Way for Generic Versions of Transdermal Patches to Treat Chronic Pain

...mbinations, non-steroidal analgesics, or as needed dosing with short-acting opioids. Fentanyl is currently a Schedule II controlled substance, which is the highest level of control for drugs with a recognized medical use. As a controlled substance in Schedule II of the Controlled Substances Act (CSA), Fent...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...drug was measured and that number was used to make dosing decisions,?said Derendorf, whose work is primarily...he drug in the blood, and from those two numbers a dosing decision is made. “We feel that’s not the optimal way go,?he said. “It doesn’t give you the full st...

Gene variations explain drug dose required to control seizures

... said. The new findings provide a direction for a dosing scheme that could be tested in the clinic to assess whether pharmacogenetic diagnostics can improve dosing decisions, he added. In particular, it may be clinically relevant to determine whether physicians ca...

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