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Tag: "dose" at biology news

Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial

...cine. "The high rates of immune responses at all dose levels in this initial human Ebola vaccine study s...ecipients who received the full three doses at all dose levels. ...

Horse antibodies against the bird flu virus H5N1 are effective as treatment in mice

...( http://respiratory-research.com ) reveals that a dose of 100 µg of horse anti-serum effectively protects...a infected dog kidney cells in vitro with a lethal dose of H5N1 and simultaneously exposed the cells to horse antibodies against H5N1. Lu et al.'s results s...

H5N1 avian flu virus vaccine induces immune responses in healthy adults

...e volunteers who received an initial and a booster dose of the highest dosage of the vaccine tested in the...responses were seen most frequently at the highest dose of this vaccine. We are investigating other options that may allow us to reduce the dosage--for exam...

Plants give pests sock in the gut

... When used in conjunction with the Bt-toxin, a low dose of Mir1-CP was able to achieve a very high mortality rate in the insects, as well as an extremely low growth rate. "In the long run, the enzyme degrades the insect's peritrophic matrix and retards the caterpillar's ability to generate a new one," s...

Duke to test bird flu vaccine dosing

...tium and leader of the Duke study. "If the smaller dose stimulates immunity against the virus, then more people could be immunized with existing supplies if a pandemic occurs," he said. The study will use an inactivated flu virus vaccine based on a strain taken from a Vietnamese patient in 2004. "There i...

Cellular scale drug delivery from the inside out

Delivering a dose of chemotherapy drugs to specific cancer cells without the risk of side affects to healthy cells may one day be possible thanks to a nanoscale drug delivery system being explored by researchers at the U.S. Department of Energy's Ames Laboratory. Usi...

Portable cocaine sensor developed at UC Santa Barbara

...sage. The test to check the ratio of a therapeutic dose versus a lethal dose is a process that takes six hours. With the new sensor, the blood level of the drug could be immedia...

Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

...ly assigned to receive by injection either a daily dose of 10 µg/kg of G-CSF or placebo (an inactive substance) for 5 days. The patients were treated between February 2004 and February 2005. Treatment with G-CSF produced a significant mobilization of bone marrow stem cells. The researchers found that thi...

Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned

...viduals in the group receiving the highest vaccine dose produced ricin-neutralizing antibodies in their bl...ms had responded. Four of five in the intermediate dose group produced antibodies, while one of five in the lowest dose group did so. The human-produced a...

Serious adverse reactions to smallpox vaccine appear to be limited

...volunteers in 55 jurisdictions received at least 1 dose of smallpox vaccine. VAERS received 822 reports of adverse events following smallpox vaccination (overall reporting rate, 217 per 10,000 vaccinees). A total of 590 adverse events (72 percent) were reported within 14 days of vaccination. Nonserious a...

Travelers can avoid jet lag by resetting their body clocks

... was a slightly larger phase shift with the 3.0 mg dose compared to the 0.5 dose; however, the difference ...ly significant. In addition, the higher melatonin dose made the participants slightly more sleepy in the evenings after taking the pill. Therefore, the re...

Sensors, a smart dose of medicine for cancer treatment

...ult is that patients only receive a high radiation dose where they need it and healthy tissue is preserved...ult to verify that patients receive the prescribed dose of radiation. "IMRT prescriptions are based on very complex computer simulations, so it is important...

Mouse study: New muscle-building agent beats all previous ones

... muscle growth after just two weeks at the highest dose given (50 milligrams per kilogram mouse weight). D... just one week, mice given a fifth of that highest dose had muscles 16 percent to 25 percent bigger than untreated mice, depending on the muscle group analy...

Study shows combination of immune substances to be safe

...t IL-12 primes white blood cells such that a lower dose of interferon will stimulate the same level of immune activity as a higher dose of interferon when used alone. The results come from a phase-I clinical trial, which marks the fir...

Young scientists turn to gel to ease side-effects of cancer treatment

...radiologists can judge more accurately the precise dose needed to treat the tumour, enabling them to calibrate their machines accordingly. Andrew Wilson said: "This technique should allow more rapid, accurate, and therefore safer treatment of malignant tumours." A different formula of the gel can be us...

Feds give researchers ok for safety test of adult stem cells in patients with heart disease

...f three to four patients who will receive a preset dose of stem cell therapy. They will have stem cells drawn from their own bone marrow. These cells will then be enriched in the laboratory and injected into the patients at the site of their ischemia. The Phase I study is being conducted at University ...

The nude mouse tale: Omega-3 fats save the life of a terminal cancer patient

...an clinical trials. While beginning to take high dose of fish oil and golden algae oil capsules daily, D.H. also reduced corn-based foods from his diet. Corn contains omega-6 fatty acids that Pardini said are found to increase cancer growth. Pardini is optimistic of what his findings may contribute to...

Brainstem blocks pain to protect key behaviors

...It's as if they could give themselves a six-second dose of morphine, allowing hunger to override pain." Mason and colleague Hayley Foo, research associate in NPP, studied adult male rats in containers with a wire mesh floor that enabled them to deliver radiant heat to one hind paw. The heat caused no da...

Polio vaccination strategies assessed as eradication nears

...h on the subject had been performed using only one dose of a vaccine that was less potent that the current...hers used shedding of virus after treatment with a dose of OPV to measure the immune response. Seventy-five percent of children receiving two doses of IPV, ...

Penicillin, amoxicillin: Step aside for strep throat treatment

...rugs is more effective than the traditional 10-day dose of the older antibiotics. Pediatricians at the University of Rochester Medical Center found that 25 percent of children treated for strep throat with penicillin ended up back in the doctor's office within three weeks of treatment. Children treated w...

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