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Tag: "dose" at biology news

Enzyme delivered in smaller package protects cells from radiation damage

...attle. Combined with intensive chemotherapy, high dose whole-body irradiation often is given to patients with blood and lymphatic cancers to wipe out their bone marrow cells prior to subsequent transplantation of hematopoietic stem cells, bone marrow stem cells or peripheral blood progenitor stem cells. ...

Old memory traces in brain may trigger chronic pain

...ls appeared to be pain free 30 days after the last dose of a 30-day regime of D-Cycloserine. The study, funded by the National Institutes of Health, will be published in the journal Pain this fall. (It has been published on-line.) “In some ways, you can think of chronic pain as the inability to tu...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

...e because it was inexpensive − now seven cents a dose − and needs no refrigeration. The drug works by preventing heme crystallization, which destroys the parasite by building up toxic levels of non crystalline heme. But because of the overuse of chloroquine, isolates of P. falciparum from around th...

Millions of children denied drug that costs less than $3 a year

...d return to a normal life by taking a single daily dose of a drug (phenobarbital) that costs less than $3 (£1.5; €2.2) each year. The World Health Organisation recommends phenobarbital as the treatment of choice in resource restricted countries, but this policy has been questioned because of concerns a...

Brightening prospects of using fluorescent nanotubes in medical applications

...s routinely mix it with special soap and give it a dose of ultrasound to break apart clumps of nanotubes and force them to dissolve. The result is a dark liquid that is routinely put into an ultracentrifuge that subjects them to forces a few thousand times that of gravity. Centrifuging separates out a num...

Research shows cord blood comparable to matched bone marrow

...ks that meet certain standards in relation to cell dose (or volume of the transplanted cells) and Human Leukocyte Antigen (HLA) diversity. Human Leukocyte Antigens (HLA) are a group of proteins on bone marrow cells that can provoke the immune system to respond. When doing bone marrow or cord blood tran...

Study shows lizard moms dress their children for success

...ed that female side-blotched lizards give an extra dose of the hormone estradiol to their eggs in certain ...ancaster identified two pathways by which an extra dose of estradiol from the mother can help to resolve this problem. In one pathway, females increased ...

Pistachios lower cholesterol, provide antioxidants

...tly reducing LDL cholesterol levels and the higher dose significantly reduced lipoprotein ratios," says Sa...hios are causing the effect and that they act in a dose dependent way," says Gebauer. In addition, during this study researchers, researchers looked at t...

Resistant HIV quickly hides in infants' cells

...ants in low-income countries who received a single dose of an NNRTI for prevention of mother-to-child transmission, and for whom treatment options are few." In an accompanying editorial, Paul A. Krogstad, MD, of the David Geffen School of Medicine at UCLA, noted that global elimination of pediatric AID...

A cherry on top: Tart cherries may alter heart/diabetes factors

...cherries or 10 percent cherries. The higher cherry dose was used to look for any toxic effects; none were seen. The cherries were Montmorency tart cherries grown in northern Michigan, frozen, and powdered. Michigan is the nation's largest producer of tart cherries, which are used in pies and jams as w...

Peramivir protects mice from lethal H5N1 infection

...rcent survival rate among mice after just a single dose of peramivir," said Elena A. Govorkova, Ph.D., a scientific manager in the Infectious Diseases department at St. Jude. Govorkova is the paper’s senior author. "Our findings support the use of peramivir during a pandemic, and we are currently study...

8 plants from South Africa may hold potential for treating high blood pressure

...od pressure in human patients 5-14 hours after the dose with no significant side effects. In addition, wild and cultivated garlic preparations were shown to decrease systolic blood pressure in rats. Conclusions In this study Tulbaghia violacea has shown properties related to lowering blood pressu...

WHO data confirms low level of resistance to Tamiflu

... influenza H5N1. 3,4 In one case, the prophylactic dose (75 mg daily) rather than the treatment dose (75 mg twice daily) was given to a patient already exhibiting clinical symptoms, thus under-dosing t...

High-dose anticlotting drug cuts heart attack, death risk in half

...d clotting, or thrombosis. In addition, the higher dose did not increase the risk of serious bleeding. ...terventional cardiologists give patients a loading dose of this medication before PCI to protect against blood clotting. After the procedure, most patients ...

DNA-damage test could aid drug development

...ew assay, "instead of testing one chemical and one dose in one animal, you'll be able to take one animal, get the bone marrow out and test a thousand different conditions," Samson says. "You'll be able to look in more detail at different doses given at different times in the cell differentiation process."...

Hexavalent chromium in drinking water causes cancer in lab animals

...umors in the small intestine, which increased with dose in both males and females. "We found that hexavalent chromium is absorbed from the gastrointestinal tract," said Hooth. "After it is orally administered, it is taken up by the cells in many tissues and organs." Hexavalent chromium has been br...

Biodegradable microspheres deliver time release vaccines, stimulate different immune response

...quire multiple doses might need only need a single dose in the future," says Wilson-Welder. Secondly, the finding that vaccine adjuvants can elicit a CMI provides hope for vaccines against intracellular diseases that we currently don't have effective vaccines for, like malaria, tuberculosis and even AI...

Scientists genetically engineer tomatoes with enhanced folate content

...e food." Will doctors be recommending a healthy dose of salsa for would-be pregnant women anytime soon? Probably not, the researchers say. "It can take years to get a genetically-engineered food plant approved by the FDA," Hanson said. "But before that is even a question, there are many more studies...

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice

... within the tumor and predicting an effective heat dose has limited its use. The UC Davis research, carried out in collaboration with scientists from Triton BioSystems in Boston, seeks to solve this problem. The experimental system uses bioprobes created by wedding magnetized iron-oxide nanospheres to ...

Vitamins: Science doesn't always match policy

...not thousands, of products with varied content and dose of vitamins and minerals. It's really difficult to guide customers if we don't even know what is in the vitamins they are taking. Standards would be helpful to both consumers and industry by rewarding those companies that do science-based marketing, ...

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