Researchers track how spores break out of dormant state
Tapping into the unknown world of awakening dormant bacterial spores, researchers have revealed throug...ents that result in the formation of metabolically dormant spores. They can remain dormant for extended periods and, partly because of their tough spore coat, ...Staphylococcus aureus hides out in cells
...and transport shut down, putting the bacteria in a dormant state. Simultaneously, production of toxins potentially lethal for the epithelial cells becomes strictly controlled to limit cellular damage. Mechanisms that helped the bacteria to survive and/or multiply, including metabolic and energy production fu...New vaccine prevents CMV infection and disease in mice
...ajority of adults in the United States, can remain dormant for years, if not the lifetime, of a healthy individual. However, two percent of all children are born with the virus passed on by the mother in utero, and 15 percent of those children will show symptoms such as hearing loss, mental retardation, mo...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...ng resistance to antibiotics. It lives either as a dormant spore or as a scavenger of decaying animal materia...bility to hibernate when times are hard by forming dormant spores. More than 110 of its set of almost 3700 genes are used to control spore formation and ge...For many insects, winter survival is in the genes
...y genes were turned on only during the flesh fly's dormant state. The researchers extracted and compared RNA from both dormant and non-dormant fly pupae – the developmental stage between larva and adulthood. They used a laborat...'Insulator' helps silence genes in dormant herpes virus
...ce genes that would cause it to replicate. In this dormant state, only a tiny fragment of the virus genome ?a single gene called the Latency-Associated Transcript gene (LAT) ?remains active. Scientists have long puzzled over the mechanism used to keep this small region of the genome going while nearby genes ...Latent memory of cells comes to life
...e and thereby cause a cell to activate some of its dormant capacities?says Kim Sneppen, professor in Biophysi...ese changes can be that a latent capacity that was dormant comes to life, or, conversely, that a previously active capacity shuts down. Same inheritance ?d...Brown cancer biologists identify major player in cell growth
...al role in cell growth another way. Simply forcing dormant cells to make GABP, they found, was enough to rouse cells from their slumber and get them to grow again. "So we've found a new pathway to control cell growth," Rosmarin said. "Now that we know a way to disrupt GABP and stop division, there is the ...How trees manage water in arid environments
...nced by temperature changes: the trees are largely dormant in winter and have a summer growing season. The mountain-top forest that she studied was in some ways the opposite. __IMAGE_3 "During the summer season before the heavy rains, when almost all the winter precipitation had been evaporated and the ...Scientists find potential 'off-switch' for HIV virus
...ency virus (HIV) and other viruses transition into dormant phases in their hosts. The researchers have discov...ey have hidden by going dormant. Eventually, these dormant viruses wake up and the infection returns, so it makes sense to try to keep the virus asleep if poss...Mosquito genes explain response to climate change
...t rather they are flowering, reproducing and going dormant at different times of the year than they used to. Many species will be unable to change quickly enough and will become extinct." "Climate change will change the seasonal ecology of many animals," Bradshaw said. "Rather than having a bully coming...Dig deeper to find Martian life
...en for studying. "It just isn’t plausible that dormant life is still surviving in the near-subsurface of ...on doses on Mars to calculate the survival time of dormant populations of the cells. Some strains are radiation-resistant and are able to survive the effects b...Key to zebrafish heart regeneration uncovered
...to help researchers find the key to unlocking this dormant regenerative capacity in mammals, and such an advance could lead to potential treatments for human hearts damaged by disease, the Duke scientists said. "If you look in nature, there are many examples of different types of organisms, such as axolot...Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses
...'s defenses against parasites, but these genes are dormant in healthy people. However, when turned on by so-called ghost parasites, the potent inflammatory response is medically very difficult to control. Researchers say that although chitin, a rigid chemical compound common to fungi, insects and roundwor...Bad blood between boys and girls
Women infected with dormant toxoplasmosis are more likely to give birth to boys than women who are Toxoplasma negative, according to research by S. Kankova and colleagues from the Departments of Parasitology, Microbiology and Zoology, Charles University; the Centre of Reproduct...Newly discovered behavior in cancer cells signals dangerous metastasis
... illuminates if the cell turns epithelial but lies dormant if the cell reverts to mesenchymal state. By following the reporter's illumination within cancer cells in rats, the team viewed the very process of alternative splicing as it occurred in the tumors. The researchers were able to visualize specific po...Tuberculosis: The bacillus takes refuge in adipose cells
...antibiotics in these cells, in which it may remain dormant for years. This discovery, published in PLoS ONE, ...cillus responsible for tuberculosis can hide, in a dormant state, in adipose cells throughout the body. The bacterium is protected in this cellular environment...Search on for treatment of slow-healing wounds
...cteria in biofilms activate sets of genes that are dormant in free-floating bacteria. With their new genetic instructions, biofilm bacteria form complicated slimy communities that can be 1000 times more antibiotic resistant than free-floating bacteria. "If you accept the biofilm theory of chronic wounds, ...A simple feedback resistor switch keeps latent HIV from awakening
... off state so easy to reach that the virus remains dormant all the time. This model also helps explain why some HIV patients experience short "blips" of viral activity, despite relatively low viral concentration. According to the authors, these pulses of viral activation may be due either to random increases...Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
...erminate within a few days, some spores can remain dormant for much longer periods, which poses special chall...tive only after spores have germinated; therefore, dormant spores that germinate after therapy has been discontinued can cause disease and death. This delayed ...