Tag: "dopamine" at biology news
Researchers identify protein pathway involved in Parkinson disease development
...the brain that produce dopamine. This lowering of dopamine
leads to decreased stimulation of the brain's motor cortex. Although scientists have not known the exact cause of the loss of these dopamine-producing neurons, they believe it is related to dysfunctional mitochondria and oxidative stress. Mitochondr...
'Personality-gene' makes songbirds curious
...er dopamine. Birds with a specific variant of this dopamine
receptor D4 gene show a stronger exploratory behaviour than individuals with other variants (Proceedings of the Royal Society London B, 2 May 2007). There is already evidence that variations (polymorphisms) in neurotransmitter-related genes are as...
Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys
generators (dopaminergics) in brain cells has prod...ration and the cardiac frequency through releasing dopamine
in situations of low oxygen level in the blood. After the implantation of the cellular aggregates of...
Enhancing activity of marijuana-like chemicals in brain helps treat
...um relies on the chemical dopamine. A shortage of dopamine
in the striatum can lead to Parkinson's disease, ...odulate these two circuits in opposite ways. When dopamine
is depleted, it is thought that the pathway responsible for inhibiting movement becomes overly acti...
Prenatal cocaine's lasting cellular effects
...e in rabbits causes a long lasting displacement of dopamine
receptors in certain brain cells, which alters the...ocaine exposure had altered the development of the dopamine
pathways in the brain. "In collaboration with Dr. Eitan Friedman of the City University of New Yo...
NIH announces phase III clinical trial of creatine for Parkinson's disease
...evodopa or other drugs that increase the levels of dopamine
in the brain. Many of the symptoms of PD result from the loss of dopamine, a neurotransmitter that helps to control movement. Half of the participants will receive creatine and half will receive a placebo. Neither the participants nor their doctor...
Morphine makes lasting -- and surprising -- change in the brain
...r found, were those between inhibitory neurons and dopamine
neurons. In a healthy brain, inhibitory cells woul...s of abuse, from alcohol to cocaine, also increase dopamine
release. So the net effect of morphine and other opioids, Kauer found, is that they boost the bra...
New dopamine brain target discovered
...on and Mental health (CAMH), discovered a distinct dopamine
signalling complex in the brain. Composed of two different types of dopamine
receptors, this novel target may have a significant role in understanding and treating schizophrenia...
The influence of the menstrual cycle on the female brain
...s self-administer cocaine (a drug that acts on the dopamine
system) in higher doses after estrogens have been ...on activity in the brain. Dopaminergic neurons use dopamine
as a neurotransmitter/neuromodulator. 2. Structures including the ventral striatum, the anterior c...
Dopamine used to prompt nerve tissue to regrow
...the biological activity. They also determined that dopamine
was more effective at differentiating nerve cells ...laminin. This ability means that the material with dopamine
may have a better chance to successfully repair damaged nerves. The success of dopamine
New brain-chemistry differences found in depressed women
...rmone system, and those involved in noradrenaline, dopamine
and serotonin production. "Further research on these differences, and their relationship to patients' responses to various depression treatments, is crucial to the continued improvement in the understanding of depression and the development of be...
Transplanted brain cells hold promise for Parkinson's disease
...ays. The standard treatment is L-dopa, a synthetic dopamine
that tends to minimize symptoms for three to five years. As the disease progresses and the drug becomes less effective, doses are increased and can produce more dyskinesia, loss of controlled movement. Centers such as MCG are exploring new ways to sl...
New research identifies gene important for nicotine's effects on the brain
...t receives nicotine and, therefore, focused on the dopamine
system in the brain. Dopamine is one of a number ...tion and reward processes. Nicotine activates the dopamine
system in the brain as do other drugs of abuse including cocaine and amphetamines. "Our work and...
Researchers identify neurons that assign value during learning
...o neutral stimuli--for example, neurons expressing dopamine
are required for aversive learning, whereas neurons expressing another neurotransmitter, octopamine, are required for appetitive learning (association of a stimulus with a reward). However, it was unclear whether a common set of neurons were responsi...
Cocaine high caused by interference in neuronal receiving stations
...a component of a receptor for the neurotransmitter dopamine
tends to grab onto a component of a receptor for g...searchers had long known that cocaine affects both dopamine
and glutamate receptors on neurons, but the molecular details of those effects were unknown. In thei...
Hormone linked to brain's cravings for food and other energy sources
...uld signal directly in the VTA region and activate dopamine
neuronal activity, which controls reward-associated behavior to promote interest in food as a reward. As a default, ghrelin's action may also alter seeking of drugs and substances that work through the same pathways. "We found that if we selective...
Pleasure and pain: Study shows brain's 'pleasure chemical' is involved in response to pain too
For years, the brain chemical dopamine
has been thought of as the brain's "pleasure chemi...muscle pain, the researchers show that the brain's dopamine
system is highly active while someone experiences pain ?and that this response varies between indivi...
Research links 'ecstasy' to survival of key movement-related cells in brain
...g "ecstasy," or MDMA, can increase the survival of dopamine
cells in the brain during fetal development. Be...But finding new methods to enhance the survival of dopamine
neurons is critical in developing new drugs for diseases such as Parkinson's. "While MDMA itself ...
High dopamine transporter levels not correlated with ADHD
...ble online, also found that for any given level of dopamine
transporters in the brain, ADHD patients experienc...ith control subjects. "These results suggest that dopamine
transporter levels alone cannot account for the severity of symptoms of inattention in ADHD," said N...
Leptin has powerful effect on reward center in the brain
... leptin signaling, via its receptor, occurs in the dopamine
neurons in the VTA and that it results in decrease...ivity of these neurons. "Metabolic control over dopamine
neuron function in the VTA is likely to have consequences for a broad range of behaviors and associa...
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