Study shows how retinoic acid enters a cell's nucleus
...y scientists had no idea what it did. Much like a doorway that requires a pass code to enter, CRABP-II can only move into a cell's nucleus if its amino acids are organized in a certain sequence, called a nuclear localization signal (NLS). However, CRABP-II does not have a recognizable NLS. Researchers have ...UCLA scientists reveal how Nipah virus infects cells
...o Ephrin-B2, proving that the receptor is the same doorway that the real Nipah virus enters to infect these cells. "We now can screen for small molecules that will block viral entry via Ephrin B-2 and develop them as therapeutic drugs," said Lee. "Because pigs are particularly susceptible to Nipah infection...Biologists discover new pathway into plant cells
... on their separate evolutionary paths. "This is a doorway into plant cells that we never knew existed," said Lynda Ciuffetti, an OSU professor of botany and plant pathology. "Viruses and bacteria have been known to bring proteins into cells, but this is just a protein by itself crossing the cell wall barrie...... larger pores than previously thought, providing a doorway that should allow larger and longer-acting doses of medicine to reach the protected tissue. The team's findings were reported this week in the Early Online Edition of Proceedings of the National Academy of Sciences. The discoveries are importa...