donor 2 4

Tag: "donor" at biology news

Long-term cancer risk follows stem cell transplant recipients

...or: patients who received stem cells from a female donor had almost quadrupled the risk of a second solid cancer, a risk that further increased when the patient was male. "This observation has not been previously reported in the literature and the explanation for this finding is uncertain," say the authors...

New data from NIH lab confirms protocol to reverse type 1 diabetes in mice

...y islets in type 1 diabetes. They also introduced donor spleen cells to retrain the immune system not to a...ale recipients. The female mice that received male donor cells consistently showed Y-chromosome-positive insulin-producing islet cells, indicating that the i...

Researchers create genetically matched embryonic stem cells for transplantation

...stem cells that are genetically matched to the egg donor at the genes that control recognition of cells by ...rocess that involves transferring the nucleus of a donor cell into an egg from which the nucleus has been removed. "We will not stop testing nuclear trans...

Male circumcision reduces HIV risk, study stopped early

... these findings, the evidence is now available for donor and normative agencies, like WHO and UNAIDS, to actively promote circumcision in a safe context and along with other HIV prevention strategies," Bailey said. "Circumcision cannot be a stand-alone intervention. It has to be integrated with all the ...

Edge density key to controlling gypsy moth spread

...), to reduce the number of dispersers to below the donor threshold." This would decrease edge populations and prevent the periodic surges of growth that expand the territory. Other invading species may also exhibit pulsed spreading. If researchers can determine that the Allee effect is in place, than thi...

An artificial cornea is in sight, thanks to biomimetic hydrogels

...the tissue is artificial, we don't have to rely on donor tissue." The high prevalence of laser-assisted in ...SIK, eye surgery may contribute to the shortage of donor tissue in developed nations, he notes, as this surgery disqualifies donation. A tissue-engineered ar...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

...than corneal grafts and of offsetting shortages of donor material. The study, the first of its kind: Identifies and prioritizes applications of regenerative medicine that could effectively improve health in developing countries; Assesses the feasibility of building developing countries' capacity in re...

Artificial cornea offers better results for infants, some blind patients

...is sewn into the patient's eyeball with a piece of donor tissue to hold the implant in place, like a washer. The device is made of a newer type of plastic that allows nutrients to enter the eye more quickly than previous designs. The latest procedure also includes a large contact lens placed over the corne...

Ebola-outbreak kills 5000 gorillas

...ss of our results will push some public or private donor to finally commit the two or three million dollars necessary to develop a safe and effective way of delivering Ebola vaccine to wild apes." Walsh contends that Ebola vaccination is a cost effective method of ape conservation. "People in the conser...

Fantastic Voyage: A new nanoscale view of the biological world

...ge, doctors might soon be able to track individual donor cells after a transplant, or to find where and how much of a cancer treatment drug there is within a cell. New technology described in a study published today in the open access journal Journal of Biology makes it possible to image and quantify molec...

Cloned mice created from fully differentiated cells, a milestone in cloning research

...lting new embryo contains the entire genome of the donor somatic cell it is an identical copy. This cloned ...risingly, the granulocytes were the most efficient donor cells for nuclear transfer among the different lineage cells, with 35 to 39 percent becoming a blast...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

...out its shortcomings ?particularly the shortage of donor hearts and the risk of organ rejection. "This ...e also offering patients a better alternative to a donor heart ?their own, healthy heart," she added. Professor Sir Magdi Yacoub, from the Heart Science...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...donor, without rejection, eliminating the need for donor matching and recipient immune suppression. Once transplanted, the cells promote healing of damaged or diseased tissues. "Because of the participation by top tier sites such as Rush University Medical Center, we were able to conduct a study that wa...

Are scientists making progress in being able to regenerate bone tissue?

...d there is a risk of transmitting viruses from the donor to the recipient. Given all these problems with bone grafts, scientists have attempted to engineer bone tissue. “Bone tissue engineering using bone marrow stem cells has been suggested as a promising technique for reconstructing bone defects,?say M...

Scientists discover new virus caused deaths of transplant recipients from single donor

...plant recipients who received organs from a single donor in Victoria, Australia. The previously unknown virus, which is related to lymphocytic choreomeningitis virus (LCMV), was found using rapid sequencing technology established by 454 Life Sciences and bioinformatics algorithms developed in the Greene ...

Erectile dysfunction in diabetes is due to selective defect in the brain

...onses to NMDA or sodium nitroprusside (SNP), an NO donor in both control and diabetic rats; the third experiment observed the effect of diabetes on nNOS protein in the PVN; the fourth experiment measured NMDA mediated behavioral responses in diabetic rats after restoring the nNOS protein in the PVN using v...

Antibody therapy prevents type 1 diabetes in mice

...ice developed type 1 diabetes, indicating that the donor mice still harbored pathogenic T-cells. On the other hand, when the researchers transferred a certain subset of T-cells from anti-CD137-treated mice that expressed two other receptors known as CD4 and CD25 to other immune-deficient NOD mice, it preve...

Type of stem cell found to reside in transplanted lungs

...g findings was that, in cases where the transplant donor and recipient were not of the same sex, nearly all...We were able to isolate the cells derived from the donor as far as 11,5 years after transplantation," says Lama, assistant professor in the Division of Pulmo...

OHSU surgeon implants donated tissue allografts

... only the beginning. "Teaming with surgeons in our donor communities around the country to provide this special gift of donation that enhances the life of the recipient is central to the JRF mission. We are pleased to partner with CTS in Portland and others areas to benefit these communities," he said. ...

The sturdier sex? -- Study by Pittsburgh scientists finds female stem cells work better

...he ratio of dystrophin-positive fibers per 100,000 donor cells. Only one of the 10 male populations of implanted stem cells had an RI over 200. In contrast, 40 percent of the female stem cell populations had an RI higher than 200, and 60 percent of the female populations of stem cells had an RI higher than...

1 2 3 4 5