Bioartificial kidney under study at MCG
...ther a bioartificial kidney containing billions of donor kidney cells will help intensive care patients with kidney failure survive is under study at the Medical College of Georgia. MCG Medical Center has joined a study taking place in intensive care units across the country to evaluate the efficacy of th...Spleen may be source of versatile stem cells
...d the earlier discovery: cells from the spleens of donor mice -intended to train the diabetic animals' immune systems not to attackislet cells - were actually producing new islets. The result suggestedthat the adult spleen - previously regarded as playing a fairly minorrole in regenerative medicine - might...Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
...fficulties in obtaining sufficient and appropriate donor fetal braintissue have limited the application of this therapy.These researchers previously demonstrated that mouse embryonic stemcells can differentiate into neurons when cultured under specificconditions. These same culture conditions, technically ...U-M scientist to talk about tissue engineering at AAAS
...at approach has problems both for the wound at the donor site and for the site where it is implanted. In addition to discussing the sometimes-messy real world applications of tissue engineering, Krebsbach plans to talk at AAAS about the potential for combining seemingly unrelated therapies to improve the ...Cytoplasm affects the number of vertebrae in carp-goldfish clones
... goldfish, were virtually identical to the nuclear donor species, Cyprinus carpio, in appearance and in most physical traits. The number of vertebrae in the clones, however, was in the range of the recipient species, Carassius auratus. Yong-Hua Sun, Shang-Ping Chen, Ya-Ping Wang, Wei Hu, and Zuo-Yan Zhu,...Enzyme allows B cells to resist death, leading to leukemia
...yactive compared with levels of activity in normal donor cells.The authors went on to show that inhibition of Lyn was able to restorethe process of cell apoptosis to normal and treatment of malignantcells with drugs that induce cell death decreased both Lyn expressionlevels and activity ?suggesting a direc...Tiny scaffolding allows stem cells to become working fat cells
...ther as a temporary substitute while waiting for a donor organ, or even providing a replacement organ." Along with Xihai Kang and Yubing Xie, both postdoctoral fellows in his laboratory, Kniss built a fabric-like carpet of polyethylene terephathalene (PET), or Dacron, fibers that served as scaffolding upo...Artifical cornea lets woman blind 20 years see
...ard human cornea transplants, some cannot tolerate donor tissue. The problem is not necessarily tissue reje... connecting a front plate to a back plate with the donor cornea tissue sandwiched in between. The surgeon then removes most of the damaged cornea from the pa...World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
...on in Kyoto, Japan, where he originally did living donor liver transplant training with Dr. Tanaka. Dr. Mas...piro first suggested the idea of starting a living donor islet transplant program in Kyoto while lecturing there three years ago. Cadaveric organ donors are ...Rare surgery performed to remove pancreas, prevent diabetes
...y the pancreatic islet cells either from a cadaver donor for transplantation or, as in this case, for infusion back into the same patient. The removal of the entire pancreas is an accepted, although radical last-resort, surgery to give relief from pain, usually from inflammation of pancreatitis. In the pa...First frozen egg baby born in Canada
...bies produced by older women. Finally, current egg donor programs require matching the menstrual cycle of egg recipients; this problem can be eliminated with egg freezing. ...Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells
...es 142 days to a year) were treated with unrelated donor umbilical cord blood. Cells from the donor "engrafted" or took hold in all of the patients. All of the asymptomatic newborns survived transplan...First technology to remove prions that cause vCJD from blood launched
... with diagnostic testing, such as alerting a blood donor that he or she has an invariably fatal disease. Re...nacted in the UK including leukocyte reduction and donor deferral. Many nations ban blood donations from people who lived or visited countries where BSE infe...Double triumph in stem cell quest
...line (Science, DOI: 10.1126/science.1112286). The donor "adult" cells came from patients aged 2 to 56, wit... cytoplasm of an enucleated ESC will reprogram the donor nuclei, turning the fused cell into an ESC too. The result, Verlinsky told a conference on pre-impla...Scientists discover that three overlapping signals in embryo help get the backbone right
...yo," Khokha said. "The piece they cut out from the donor embryo and transplanted into the host embryo was able to redefine the structures in the host embryo to make back structures where the belly would normally form - to induce another head, brain and spinal cord. The tissue they transplanted sent signals...Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells
...es 142 days to a year) were treated with unrelated donor umbilical cord blood. Cells from the donor "engrafted" or took hold in all of the patients. All of the asymptomatic newborns survived transplan...Scientists generate patient-specific stem cells, Science study says
...both the somatic cell and the oocyte; however, the donor was a spinal cord patient. The ten additional new lines resulted from nuclear transfer with skin cells of males or females and oocytes from biologically-unrelated females. Other improvements over the last paper include the reduced use of animal pro...SuperLigands - a database of ligand structures derived from the Protein Data Bank
...both the somatic cell and the oocyte; however, the donor was a spinal cord patient. The ten additional new lines resulted from nuclear transfer with skin cells of males or females and oocytes from biologically-unrelated females. Other improvements over the last paper include the reduced use of animal pro...Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes
...s who received islet transplantation from a single donor pancreas were insulin independent one year later, ...ing a higher number of islets prepared from 2 to 4 donor pancreases. However, for islet transplants to become a widespread clinical reality, additional advan......sion between the bone marrow-derived cells and the donor pneumocytes, said Zander, who holds the Harvey S. Rosenberg, M.D., Chair in Pathology and Laboratory Medicine at the medical school and serves on the Council of the American Society of Investigative Pathology, a prestigious organization focused upon ...