Defect in gene causes 'neuralgic amyotrophy'
...bers of the Septin family are involved in the cell division that forms the cytoskeleton and in the development.... The fact that mutations in Septin 9 prevent cell division from occurring properly can perhaps explain why so many HNA patients also have facial abnormalities....Brain size may depend upon how neural cells are cleaved
...good candidates as regulators of the plane of cell division in neural precursors," said Tsai. "And this is a ... because it has been speculated that the different division planes dictate the ultimate cell fate adoption of daughter cells," said Tsai. To determine definiti...Structures of marine toxins provide insight into their effectiveness as cancer drugs
...ments, that are essential for cellular locomotion, division and growth," explains Allingham. "Because cancer cell masses grow faster than other cells in the body, actin provides an excellent target for drugs that could inhibit such rapid growth." Adds Allingham: "These marine toxins can knock out the lynchp......am eggs are popular among scientists studying cell division and the proteins associated with it. Female clams ... female. By inducing the clam eggs to undergo cell division at the same time, scientists can study millions of cells in the same stage of division. Clam eggs ar...Scientists find microRNAs regulate plant development
... numerous genes that control the processes of cell division and cell expansion in specific plant tissues at specific stages during the plant life cycle - e.g. for leaves, roots, and floral organs to develop in the correct patterns and correct time sequence. Research reported in The Plant Cell shows that micro...New defibrillator signals doctor of patient's irregular heartbeat or device malfunction
... Dr. Niraj Varma, associate professor of medicine, division of cardiology, Loyola University Chicago Stritch School of Medicine, and director of the cardiac electrophysiology lab, Loyola University Health System, Maywood, Ill. The notification signal is automatically generated, even if the patient is unaware...Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005
...e arrested in the prophase I stage, before meiotic division is complete, when the enlarged nucleus is called the germinal vesicle (GV). Bjorn Heindryckx, a PhD student at the Infertility Centre at Ghent University Hospital, Belgium, and his colleagues, matured GV oocytes in culture in the laboratory for 44 h...Scientists succeed in cloning human embryos from eggs matured in the lab
...e arrested in the prophase I stage, before meiotic division is complete, when the enlarged nucleus is called the germinal vesicle (GV). Bjorn Heindryckx, a PhD student at the Infertility Centre at Ghent University Hospital, Belgium, and his colleagues, matured GV oocytes in culture in the laboratory for 44 h...Specialized immune-system B cells play double-barreled role
... Medical Center immunologists have discovered. The division of labor between B-1a and B-1b cells they have uncovered offers basic insights that could contribute to more rational development of vaccines, they said. B cells are the arms factories of the immune system, producing antibodies that target invading ...Mosaic mouse technique offers a powerful new tool to study diseases and genetics
...in the duplication of each chromosome. Before cell division is complete, a special enzyme causes the exchange, or recombination, of the two engineered chromosomes. If one of those chromosomes contains a bad copy (mutation) of a gene, the recombination event could cause an offspring to inherit two bad copies o...Cancer related gene p53 not regulated as indicated by previous tissue culture research
...d properly repaired, these DNA breaks can let cell division spiral out of control, ultimately causing cancer. ...e production of other proteins that will halt cell division if the DNA damage can be repaired. Or, if the damage is too severe for the breaks to be repaired, c...Researchers pioneer new gene therapy technique using natural repair process
... father) and they must duplicate these during cell division so that the subsequent cells will also have two each. The wounded chromosome takes advantage of the healthy copies created in preparation for division, and uses them as a template to repair the break in the DNA strands. In the new gene therapy techn...Pair of cancer genes found to drive both cell migration and division
...could be helpful in stopping the uncontrolled cell division found in cancers. Mutations in the genes, called P...e front of the cell and what drives it, while cell division researchers have concentrated on the furrow within the dividing cell," says Devreotes. "But we've fo...'EuroVacc 02' HIV Vaccine Trial Begins
...) was manufactured by sanofi pasteur - the vaccine division of Sanofi-Aventis - and has already been evaluated in a phase I study (EuroVacc 01) at the same clinical centres in Lausanne and London. The completed phase I study showed that the NYVAC-HIV-C is safe and immunogenic. The DNA-HIV-C vaccine was develo...Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers
...effrey H. Fair, associate professor of surgery and division chief of abdominal transplant surgery. Moreover, he said, the PEP cells robustly engraft within the liver and were not recognized by the immune system as foreign. "Within a few weeks, PEPs became hepatocytes," Fair added. "They went from something ...Human Eggs Can Develop From Ovarian Surface Cells In Vitro
...went on to successfully complete the first meiotic division to become mature human eggs -- capable of being fertilized and developing into an embryo. These in vitro findings support earlier in vivo studies by Bukovsky and colleagues that OSE cells are bipotent; capable of differentiating along two development...15-year hunt finds cause of pseudothalidomide syndrome
...then thalidomide might affect chromosomes and cell division like ESCO2 in Roberts syndrome, Jabs speculates. ...riginal and the new copy away from each another as division proceeds. However, in cells from people with Roberts syndrome, the chromosome copies are frequently...Mother birds increase progesterone to hatch females
... progesterone during the first meiosis -- the cell division that divides the sex chromosomes and genetically determines the sex of an offspring -- produces significantly more females. "For years, behavioral biologists have been trying to figure out how the females of a few species, such as the Seychelles war...Two chemicals boost immune cells' ability to fight HIV without gene therapy
... their protective functions. The massive amount of division prematurely shortens these cells' ends, or telomeres, ultimately exhausting the immune system. UCLA's previous research shows that telomerase rejuvenates the telomeres and allows the immune cells to remain youthful and active as they replicate under......base pairs stores genetic information. During cell division genetic material is copied and the enzymes respons... the DNA, the magnitude of which increases as cell division progresses. These forces can delay the process of cell division and under certain conditions even st...