Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine
...form disease but rather a disease that follows two distinct clinical courses in patients. Some patients require no treatment and have a lifespan of more than 20 years after diagnosis. Since the disease most often strikes older adults, the patients whose disease follows this course usually die with the disease...New research questions basic tenet of neuron function
.... 17 issue of the journal Neuron suggests that two distinct types of synaptic vesicles are responsible for the...hysiological techniques, the researchers found two distinct types of vesicles. "The functional differences of these two sets of vesicles may be the result of d...New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
... found many diverse kinds of RNAs transcribed from distinct regions of the genome, creating a complex pool of overlapping transcription. While the team validated many known protein-coding transcripts that contribute to this complex pool, they also discovered that: Seventy-five percent of all of the RNA that...Same mutation aided evolution in many fish species, Stanford study finds
... ago. Because ocean fish quickly evolved into such distinct populations when they colonized new freshwater lakes and streams, they are an ideal model for understanding how animals adapt to their unique environments. The recent work carries a few surprises. Kingsley said that the gene in question, called Eda,...Alcohol's effects on gene expression in the central nervous system
...ntal cortex, and ventral tegmental areas show that distinct biological pathways are associated with alcohol's action in specific brain regions and certain mouse strains. "We were able to use gene expression profiling to determine that alcohol produces multiple effects on different biological processes," said...First real-time view of developing neurons reveals surprises, say Stanford researchers
...ement. When the tiny square moved left to right, a distinct population of neurons turned fluorescent colors to indicate their activity. Moving the square the reverse direction triggered a different population of neurons to light up. "At first we felt like we let some air out of our own tires with this findin...Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
...therapeutic," says Naviaux. "How are their spectra distinct from cancer?" A difficulty still ahead is viewing cancer cells in fluids taken directly from the body, rather than isolated by type in a flask. This problem will be solved by winnowing out unlikely particles through size and frequency. ...Scientists identify new model Of NK cell development
...igiuri's laboratory, scientists had identified two distinct subsets of human NK cells (referred to as CD56 bright and CD56 dim cells) and they observed that the bright subset appeared much more frequently in lymph nodes than in bone marrow or circulating blood. In other words, they had a hunch traditional th...New RNA polymerase discovered in plants
...NA polymerases Pol I, II, and III perform the same distinct , though separate, functions in different species....laborators have indirect evidence that Pol IV is a distinct RNA polymerase, they still have many aspects of Pol IV to unravel. "We know what happens when its g...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...ervation and overlap in yeast, worm, and fly in 71 distinct "network regions" that included such essential functions as protein degradation, RNA polyadenylation and splicing, protein phosphorylation and signal transduction, DNA synthesis, nuclear-cytoplasmic transport, and protein folding. Such networks enric...Unexpressed But Indispensable -- The DNA Sequences That Control Development
...xpression, in keeping with their presumed roles in distinct developmental processes. The discovery of these developmentally important sequences opens several avenues of new research. For example, analyzing the sequence and location of these CNEs may help point the way to other non-coding elements that remain...Scientists solve structure of key protein in innate immune response
...efenses. "Macrophages and monocytes can recognize distinct structural patterns in various molecules from pathogenic microorganisms," explains Dr. Jie-Oh Lee of the Korea Advanced Institute of Science and Technology. "LPS is the most famous and probably the most important inducer of the innate immune response...Asthma gene clusters identified
...bilized with medication. The analysis revealed two distinct gene expression profiles in these groups of children, according to Gurjit K. Khurana Hershey, MD, PhD, director of the Center for Translational Research in Asthma and Allergy at Cincinnati Children's and senior author of the study. "We found that c...Cricket's finicky mating behavior boosts biodiversity
...rbreed. After a point, however, members of the two distinct species no longer mate with each other. This discovery led Mendelson to name one of her graduate-school papers after the pop song "Will You Still Love Me Tomorrow?" The Nature article was given the more conservative title of "Rapid Speciation in an ...Advances in the characterisation of the oyster mushroom genes
... is precisely this fifth gene that is structurally distinct from the others: it lacks a fragment at its end. It should be pointed out that the genes that are together and the lone one are located on chromosomes where there are also genes responsible for the breaking down of lignin. This is of great interest ...Biodiversity hotspots identify conservation priorities
...astern Afromontane regions have been identified as distinct hotspots in their own right. The scientists delved beyond species to identify genera and families that are unique to the hotspots, concluding that hotspots also hold a disproportionately high degree of unique evolutionary history. Madagascar and the...Computational Method Speeds Mapping of Cell Signaling Networks
...ways to uncover molecular relationships. This is a distinct advantage according to Pe'er, who notes, "Unlike classical biochemical approaches where you need to know all of the intermediate players in a network, this system can detect indirect influences" between molecules. Pe'er suggests a similar technique ...Marburg haemorrhagic fever in Angola update
...ch straightforward measures are complicated by the distinct features of this disease. The sudden onset, dramatic symptoms, and rapid deterioration of patients, and the absence of a vaccine and effective treatment, invariably incite great anxiety in affected populations. This anxiety, in turn, can interfere wi...New insight into regulation of blood stem cells
...of blood cell. Instead, c-Myb is critical for very distinct steps in the formation of specific types of blood ... a key regulator of hematopoiesis and acts at many distinct points to control HSCs. "It is remarkable that a single transcription factor controls the diverse pr...... a young bird morph into the recognizable and very distinct melodies of its parents. Neuroscientists at the McGovern Institute for Brain Research at MIT now have come one step closer to understanding that process. They've shown for the first time how a particular brain region in birds serves as the source of ...