Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients
...dy's immune system attacks healthy nerve cells and disrupts normal nerve signaling. Patients experience a wide range of symptoms—including tingling, paralysis, pain, fatigue, and blurred vision—that can appear independently or in combination, sporadically or persistently. Although symptoms appear in no partic...Rats infected as newborns grew up vulnerable to memory problems during an immune challenge
...ETA in the brain's hippocampus, a key memory area, disrupts the consolidation of memories following a learning experience. Thus it appears that there may be an optimal range for IL-1BETA, with either too much or too little inhibiting memory storage. Bilbo says, "The take-home message is that immune responses ...Studies reveal methods viruses use to sidestep immune system
...h in Galveston. The findings shed light on how HCV disrupts a separate immune pathway in infected liver cells, again by unleashing the NS3/4A protease to cleave another protein essential to triggering immune defenses. Again they found that protease inhibitors could reverse the effects of NS3/4A, allowing this...BRCA1 causes ovarian cancer through indirect, biochemical route
...is that the gene actually acts indirectly, that it disrupts interactions between different cell types." The well-known breast cancer gene, BRCA1, not only gives carriers of its mutated form a four in five chance of developing breast cancer, it also confers a 40 percent risk of developing ovarian cancer by th...