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Tag: "disrupting" at biology news

Exploring the dark matter of the genome

...uses that hop around the genome and are capable of disrupting gene function. "Drosophila is ideal for studying genomics for many reasons, and especially for studying heterochromatin," says Susan Celniker, a scientist in Berkeley Lab's Life Sciences Division and a longtime member of the Berkeley Drosophila G...

How plague-causing bacteria disarm host defense

... immune system beyond its previously known role of disrupting the host cell's normal structure, which interferes with the cell's innate ability to engulf and destroy invading bacteria. "The question now becomes, why is Gaq targeted by YpkA"" ...

DNA repair proteins monitored at double-strand break

... leads to defects in double-strand break repair by disrupting the signaling processes triggered by the break. "A lack of functioning ATM causes ataxia-teleangiectasia, a disease that causes a variety of debilitating problems, such as neurodegeneration, cancer and sensitivity to irradiation leading to double-str...

Toxoplasmosis infection trick revealed by scientists

...ntial to develop therapeutics that are targeted at disrupting this mechanism, therefore thwarting infection." Toxoplasma gondii, the parasite that causes toxoplasmosis, is one of the world’s most common parasites. Around a quarter to half of the world’s population is thought to be infected, and around 1% of ...

Study warns deep-sea mining may pose serious threat to fragile marine ecosystems

...cean currents, these nutrients could drift widely, disrupting the food chain and potentially damaging ecosystems that lie within other countries?economic zones or in international waters. This poses additional problems, because while a state has the right to exploit its own resources, international environmenta...

Pitt study notes decline in male births in the US and Japan

...l factors, such as prenatal exposure to endocrine- disrupting environmental pollutants may impact the SRY gene ?a gene on the Y chromosome that determines the sex of a fertilized egg. Other environmental factors that also may affect the viability of a male fetus include the parents?weight, nutrition and the use...

Anti-herpes treatment reduces HIV levels in women infected with both viruses

...nfection may also increase HIV-1 infectiousness by disrupting the genital mucosa and increasing the levels of HIV in the genital tract3, allowing easier transmissibility of the virus. In addition, the HIV viral load in the blood of HIV-1 infected patients increases, at least temporarily, during episodes of HSV ...

MicroRNA helps prevent tumors

...protein was produced. Next, she tested whether disrupting let-7's ability to repress Hmga2 would lead toward tumor creation. In a standard in vitro test of cancer-causing genes, colonies of mouse cells that expressed normal or shortened Hmga2 did not grow significantly, while cells in which Hmga2 contained ...

'Juiced-up' battery fueled by sugar could power small portable electronics

...actions. If we are busy with something we suppress disrupting external influences. If we are tired, we can no longer do this. Social-psychologist Veling proved that the brain selects incoming information to remember useful things. Distracting information is refused and neutral information may enter. In the ev...

Molecular tools make the cut

...actions. If we are busy with something we suppress disrupting external influences. If we are tired, we can no longer do this. Social-psychologist Veling proved that the brain selects incoming information to remember useful things. Distracting information is refused and neutral information may enter. In the ev...

Brain fends off distractions

...actions. If we are busy with something we suppress disrupting external influences. If we are tired, we can no longer do this. Social-psychologist Veling proved that the brain selects incoming information to remember useful things. Distracting information is refused and neutral information may enter. In the ev...

Smokers quit after damage to brain region

... platform. "It's really intriguing to think that disrupting this region breaks the pleasure feelings associate...result, it might be possible to target one without disrupting the other. Hanna Damasio, co-director of the institute and holder of the Dana Dornsife Chair in Ne...

Cancer cells forming blood vessels send their copper to the edge

.... Compounds that reduce copper in the body without disrupting the body's normal functions can inhibit the growth of blood vessels ?and some of these compounds are even in clinical trials for use in cancer therapy. Yet, the biological basis for this sensitivity of angiogenesis to copper has been an enigma. In...

Some butterflies travel farther, reproduce faster

... The work is important because human activity is disrupting many animal habitats, forcing more and more species to do what the fritillary has long done in its naturally fragmented environment. Scientists want to know how this fragmentation influences a species' evolution. "We may be selecting for genes that...

'Trojan Horse' agent halts bone metastasis in mice

...nside, the "Trojan Horse" toxin destroys the cell, disrupting the ability of tumors to form blood vessels to supply the nutrients they need to grow. Animal studies previously conducted by the researchers have shown that the protein can selectively destroy blood vessels feeding human solid tumors. In this stu...

Molecular structure reveals how botulinum toxin attaches to nerve cells

...r neurons, interfering with nerve transmission and disrupting the communication between the nerve and muscle fibers throughout the body. Poisoning with botulinum toxins leads to an often-fatal paralysis, which is one reason they are considered among the highest biodefense research priorities by the U.S. governm...

Dragonfly's metabolic disease provides clues about human obesity

...lder studied is Libellula pulchella. The microbes disrupting the dragonfly metabolism may hold clues for scientists looking for the root causes of metabolic diseases in humans, according to Marden and Schilder's paper "All of these symptoms, and the underlying processes behind these symptoms that we're seei...

China's environmental challenges

... (Peking University) tackle the topic of endocrine disrupting chemicals in China's rivers and coastal waters, looking particularly at the impacts on Chinese sturgeon, night herons, and carp--all of which have exhibited sex organ malformations. Frontier's Finishing Lines columnist Katherine Ellison highlights G...

A wolf in sheep's clothing: Plague bacteria reveal one of their virulence tricks

...ce factors, which kill by -- among other things -- disrupting the cells' normal structure. One of these proteins... After establishing this effect, Prehna set about disrupting it by mutation. Using the structure to guide him, he changed three amino acids of YpkA that contacte...

Study provides first look at the 'birth' of a retina cell

...roop is enthusiastic about finding new methods for disrupting the disease process. There may also be opportunities to promote the production of new rods and cones when others die off. In future studies, the Kellogg scientist plans to use this new mouse model in conjunction with other mouse models of specific ...

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