disrupt 2 5

Tag: "disrupt" at biology news

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

...ty there. In future studies, they plan to alter or disrupt neurons or structures in the social-processing regions of the monkeys' brains, and explore whether the resulting behaviors mimic the symptoms of autism. Also, he said, the researchers can explore the environmental contribution to autism by studying t...

Reversal of role for a viral protein associated with the development of lymphoma

... taken into account when evaluating mutations that disrupt gene expression and produce a dysfunctional or non-functional protein. "Current data indicate that at least 15 percent of disease-causing mutations occur at standard signals where intron removal takes place through direct splicing. Mutations at rec...

Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors

... lead to more targeted, less toxic treatments that disrupt the process by which stem cells could give rise to...stoma could enable researchers to more effectively disrupt the genes and proteins that fuel its growth. Stem cells are immature cells that have the potential ...

Carnegie Mellon University research reveals how cells process large genes

... taken into account when evaluating mutations that disrupt gene expression and produce a dysfunctional or non-functional protein. "Current data indicate that at least 15 percent of disease-causing mutations occur at standard signals where intron removal takes place through direct splicing. Mutations at rec...

New clue to cocaine addicts' quirky behavior

...e on this circuitry demonstrated that the drug did disrupt this normal plasticity. They found that the cocaine induced abnormal enhancement of neuronal connections--a phenomenon called long-term potentiation (LTP). The researchers also performed behavioral studies on the cocaine-sensitized rats, to explore ...

USC researchers determine mechanism of action of chemotherapy drug

...rovide support for the hypothesis that agents that disrupt metabolism and increase intracellular zinc levels have potential applications as anticancer therapeutics." ...

Attacks of King George III's madness linked to key metabolism molecule

...all of them stemming from inherited mutations that disrupt the body's manufacture of heme. A reddish pigment that contains iron, heme is a building block of the oxygen-carrying hemoglobin in red blood cells. The complex synthesis requires eight different enzymes, and when any of them is deficient because of ...

Study: Harmless virus kills some cancers

...ulation, infect them, express its own genes, which disrupt the host cell's life cycle and kill it. Scientists have suspected that AAV2 has cancer-suppressing properties. In previous studies, Meyers and his team found that one of the ways AAV2 suppresses cancer is by inhibiting the normal process of DNA dupl...

Researchers discover key gene involved in bark beetle pheromone production

...is, which will allow further research into ways to disrupt the production of aggregation pheromone. In addition to Blomquist, Anna Gilg, Jeremy Bearfield, Claus Tittiger and William Welch co-authored the article, "Isolation and functional expression of an animal geranyl diphosphate synthase and its role in ...

Currents could disrupt ocean food chain

... ultimate mixing of the water. That would not only disrupt the Atlantic Conveyer current, Schmittner said, it... they melted, sufficiently freshening the water to disrupt the conveyer," Schmittner said. "There is some evidence backing that up," he added. "Deep ocean sed...

Stealth Worms May Improve Insect Pest Control

...s nematode and other plant-parasitic nematodes and disrupt their life cycle and their infection into the citrus roots." This study is using commercially available nematode products along with isolates of nematodes collected from Arizona's sky island (mountain) regions. For the lettuce trials, native nematode...

Unchecked DNA replication drives earliest steps toward cancer

...he DNA duplication process ?breaks in the DNA that disrupt genes, for example. Unless halted, this error-generating process leads to an accumulation of mutant genes in the cell and, eventually, cancer. A report on the new findings appears in the April 14 issue of Nature and is featured on the journal's cove...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

... solving the structure, we now understand how they disrupt the folding and stability of the RNA and why they are disease mutations." For telomerase to be active, it needs the telomerase RNA and a protein called human telomerase reverse transcriptase, which is related to the reverse transcriptase protein tha...

Shutting down the HIV assembly line

...gs to combat the virus. No existing anti-HIV drugs disrupt particle assembly or the movement of Gag in the cell. "We have hopes of identifying compounds that inhibit this Gag-AP-3 interaction and that may lead to new efforts to treat HIV infection," Spearman said. Such drugs should be very specific, he sai...

Scientists journey to southern Africa to unravel the secret world of elephant communication

... noises, and possibly seismic vibrations, that can disrupt and frighten wild herds located far away. David Larom and others argue, therefore, that the use of helicopters in areas inhabited by elephants should be carefully monitored and controlled. Seismic research also may prove useful as a deterrent agains...

Multi-purpose protein regulates new protein synthesis and immune cell development

...y and first author of the paper. "All these things disrupt protein folding and put stress on the cell. By doing so, they activate the UPR." Several years ago, Kaufman and his research colleagues discovered that IRE1 triggers the unfolded protein response by splicing a segment of messenger RNA called XBP1. T...

Researchers identify protein crucial for survival of Lyme-disease bacterium

... needs to sustain itself, then in theory you could disrupt that cycle by blocking whatever that mechanism is," Dr. Norgard said. Traditionally, scientists studying pathogens have looked at genes that affect how the infecting organisms behave once inside a human host. What tends to get ignored, Dr. Norgard s...

Researchers discover chemical compounds that affect plant growth

...focuses on the use of small molecules to modify or disrupt the functions of specific genes or proteins. NASA ...trasts with classical genetics, in which mutations disrupt gene function," Raikhel said. "The underlying concept is that the functions of most proteins can be ...

Defensins neutralize anthrax toxin

...ntrol. Now we can develop targeted therapeutics to disrupt the function of this viral protein." The researchers surmise that the first use of future therapies from these studies will be in lymphoproliferative disease in transplant and immunocompromised patients because this is a clear case of EBV-driven B-ce...

Epstein-Barr virus protein crucial to its role in blood cancers

...ntrol. Now we can develop targeted therapeutics to disrupt the function of this viral protein." The researchers surmise that the first use of future therapies from these studies will be in lymphoproliferative disease in transplant and immunocompromised patients because this is a clear case of EBV-driven B-ce...

1 2 3 4 5 6