Invasive species harms native hardwoods by killing soil fungus
... "but one possibility is that invasive species may disrupt fragile ecological relationships that evolved over...plying that the weed uses phytochemical poisons to disrupt native plants' mycorrhizal associations and stunt their growth. When the study was subsequently re...Researchers develop new method to help find deadly malaria parasite's Achilles heel
...a new approach to help in the design of drugs that disrupt proteins in pathogens while sparing patients from side-effects. The malaria parasite has a four-stage life cycle, and the Fields group analyzed only the proteins expressed in the phase that infects human red blood cells, an infection that leads to f...Biologists discover new pathway into plant cells
... and bacteria can penetrate cell wall barriers and disrupt plant cells, but never before has a protein been found that could do this by itself. When more research is done, this may provide a new tool to penetrate plant cells and possibly manipulate their behavior in some beneficial way ?to grow faster, resi...Plants, too, have ways to manage freeloaders
... including heavy use of nitrogen fertilizer, could disrupt these relationships and create plants with a reduced ability to choose among root bacteria. "It's important to look at this from an evolutionary perspective and to think about plants making choices both before and after infection," said Ellen Simms,...Scientists show how thinking can harm brain cells
..., these impulses can inflict injury on neurons and disrupt neurologic function. Understanding this mechanism could provide a new path for drugs to treat the diseases. Working in collaboration with researchers at the University of California at San Diego, the Rochester scientists propose a strategy of chemic...Penn researchers study the use of ultrasound for treatment of cancer
...urn on low-intensity ultrasound vibrations you can disrupt the blood flow through these vessels," explained Andrew Wood, DVSc, PhD, a co-investigator of the study and based in the University of Pennsylvania School of Veterinary Medicine. Sehgal adds, "This approach is in keeping with the latest study of can...Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection
...protein nucleases (ZFNTM) designed to specifically disrupt the CCR5 gene. In its anti-HIV preclinical resear...ram, Sangamo has designed ZFNs that can be used to disrupt the CCR5 gene, a receptor required for HIV entry into immune cells. The researchers found that ZFN-......erm health threats," McCabe said. "Lead appears to disrupt the immune system's checks and balances, which must be in place if we are to successfully fight off pathogens. Our continuing research is aimed at discovering how lead upsets the balance of cells charged with protecting us." Graduate student David G...New study examines how sense of smell affects mating and aggression in mice
...nt male mice that had been genetically modified to disrupt the functioning of their MOE with the behavior of normal mice, also known as wild-type mice. Wild-type female and male mice were placed at separate times in cages with the male mutants. When comparing the mutant males with wild-type males, study re...Scientists determine structure of enzyme that disrupts bacterial virulence
...omenon is called quorum-sensing. "Being able to disrupt quorum-sensing in these organisms could potentially augment our current treatments, and knowing the structure of this quorum-quenching enzyme will greatly help in developing more effective enzymes for this type of application," explained Walter Fast,...Sickle cell disease corrected in human models using stem cell-based gene therapy
... applicable process. The transferred gene must not disrupt the cells' normal functions," explained Isabelle Riviere, PhD, Co-Director of the Gene Transfer and Somatic Cell Engineering Facility and a study co-author. The new gene had two functions -- produce normal hemoglobin and suppress the generation of ...Researchers offer proof-of-concept for Altered Nuclear Transfer
...ules are designed to target an individual gene and disrupt its ability to produce protein. In effect, the gene is shut off. Jaenisch and Meissner designed a particular form of siRNA that shut off this gene in the donor nucleus and then incorporated itself into all the cells comprising the blastocyst. As a re...K-State researchers study insects' immune system
...tion in immune responses may help identify ways to disrupt disease transmission by blood-feeding insects. Kno...how a pathogen can survive might result in ways to disrupt the transmission of diseases, Kanost said. "Insects are the most abundant kind of animal," he said....New molecule may aid in production of biofuels and fungi-resistant plants
...o chitin through highly specific interactions that disrupt the chitin structure making the individual sugar chains in the chitin polymer more amenable to enzymatic degradation. The discovery of this new protein that participates in chitin degradation has many potential applications. For example, transgenic ...Researcher uncovers details of how cancer spreads
...s might aid future research on drug therapies that disrupt the sequence of events that lead to metastasis. A study published in the journal Developmental Cell (Vol. 9, August 2005) reveals how connective tissue holding a cancer cell in place might degrade, unmooring the diseased cell and allowing it to spre...Gene that helps mosquitoes fight off malaria parasite identified
...site. They believe that such a mosquito could help disrupt the transmission of malaria to humans. "An immune-responsive serpin, SRPN6, mediates mosquito defense against malaria parasites" was written by Eappen G. Abraham, Sofia Pinto, Anil Ghosh, Dana L. Vanlandingham, Aidan Budd, Stephen Higgs, Fotis C. Ka...MicroRNAs have shaped the evolution of the majority of mammalian genes
...d do nonconserved sites also have the potential to disrupt protein production? In the new study, scientists ...hat a matching sequence is generally sufficient to disrupt mRNA's ability to make protein. But while Grimson showed that, at least in the lab, microRNAs coul...Hopkins scientists uncover 'tags' that force proteins to cell surface
...of the very end of a protein, it seems unlikely to disrupt how the rest of the protein folds in a three-dimensional structure, but that's what most scientists think goes wrong if a protein doesn't go to the surface," says Li. "But now we know the problem might just be a faulty transportation signal." Given ...Discovery of T-cell 'traffic control' boosts new drug promise
...cells attack the myelin coating of nerve cells and disrupt their function. Neither Goetzl nor Rosen is involved in the on-going clinical trials of the new drugs and neither has financial ties to the companies that manufacture them. Controlling this process with drugs offers "enormous potential" against deva...Plant pathologists evaluate eco-friendly alternatives to methyl bromide
...d on methyl bromide's ability to deplete ozone and disrupt the UV protective ozone layer. The EPA determined that, under the Clean Air Act, this fumigant must be phased-out by 2001, but in compliance with the Protocol, the complete phase-out was scheduled for 2005. Currently, only uses deemed as critical by ...