disorders 2 6

Tag: "disorders" at biology news

Prozac's target revealed

...nt therapies for neurodegenerative and other brain disorders including Alzheimer's and Parkinson's disease. It has been known for some years that Prozac (fluoxetine) is likely to relieve the symptoms of depression by somehow causing more neurons to be present in a particular region of the brain (the "dentate ...

Stem cells found in adult skin can be transplanted and function in mouse models of disease

...ype for treatment of nerve injuries, demyelination disorders such as multiple sclerosis, and even spinal cord injury," said Dr. Freda Miller, the study's principal investigator, a senior scientist in Developmental Biology in the SickKids Research Institute, a professor of Molecular and Medical Genetics, and Ph...

Brain-computer link lets paralyzed patients convert thoughts into actions

... optimize the recovery of patients with paralyzing disorders such as stroke, spinal cord injury or neuromuscular disease. The available assistive technologies, however, provide neither sufficient independence nor mobility. "Thanks to the generosity and pioneering spirit of our initial trial participants, wh...

Pathway toward gene silencing described in plants

...s, contributing to tumor growth. And certain blood disorders resulting from defective genes expressed in adults might be alleviated if versions of those same genes that are only expressed very early in development, but are then silenced in adults, could only be turned on again. "The pathway we are studying i...

'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage

...the copying mechanisms of DNA, can lead to serious disorders such as cancer. The research, just published in the Proceedings of the National Academy of Sciences (PNAS), was led by doctoral student Maria Lind and Henry F. Schaefer III, Graham-Perdue Professor of Chemistry. Other authors on the paper are doctor...

Natural pine bark extract relieves muscle cramp and pain in athletes and diabetics

...Germanystudied the effects of Pycnogenol on venous disorders and cramping in two separate studies. The first study consisted of 66 participants who had experienced normal cramping at some point, had venous insufficiency, or were athletes who suffer from exercise-induced cramping. The first two weeks of the s...

New roles for growth factors: Enticing nerve cells to muscles

...ity in the brain may also underlie autism spectrum disorders and mental retardation. The multitasking members of the FGF growth factor family regulate blood vessel formation, wound repair, lung maturation, and development of skeletal muscle, blood and bone marrow cells. The Salk study adds on more job to an a...

Wild vs. lab rodent comparison supports hygiene hypothesis

...ttacks tissues in the body. Examples of autoimmune disorders include lupus, insulin-dependant diabetes, rheumatoid arthritis and scleroderma. "The most commonly accepted explanation for this high incidence of allergy and perhaps autoimmune disease is the hygiene hypothesis," Parker said. But this hypothesis h...

New stem-cell findings can help the body to cure itself

... us develop new drugs for things like neurological disorders and anaemia," says Professor Jonas Frisén. In mos...ght number of cells are produced. As many serious disorders cause a reduction in the production of new cells, scientists are keen to develop drugs that stimulat...

New research examines genetics of successful aging

...ty genes for cardiovascular disorders, psychiatric disorders and the accumulation of tissue damage due to oxida...tte smoking, excessive drinking and serious mental disorders on successful aging in both sexes. "The finding that genetics, lifestyle decision making, and thei...

Discovery of agile molecular motors could aid in treating motor neuron diseases

...n diseases are a group of progressive neurological disorders that destroy motor neurons, the cells that control voluntary muscles for such activities as speaking, walking, breathing, and swallowing. When these neurons die, the muscle itself atrophies. A well-known motor neuron disease is amyotrophic lateral sc...

'Sticky' mice lead to discovery of new cause of neurodegenerative disease

...Researchers have long known that neurodegenerative disorders can be caused by the gradual yet persistent accumulation of misfolded proteins in neurons that eventually triggers cell death. But this new mechanism points to errors in executing the genetic instructions, which are distinct from known causes of neur...

NHGRI announces latest sequencing targets

...disease ?from infectious diseases and neurological disorders to mental illness and cancer," said NHGRI Director Francis S. Collins, M.D., Ph.D. The gibbon genome is unique because it carries an extraordinary high number of chromosome rearrangements, even when compared to other primates. These rea...

Autistic brain has fewer neurons for processing emotion

...ded brains of individuals with epilepsy or similar disorders associated with cell loss in the amygdala. Paradoxically, past research using magnetic resonance imaging with children has shown that the amygdala in young males with autism is abnormally large in volume due to precocious maturation. "It is somewh...

Neurons grown from embryonic stem cells restore function in paralyzed rats

...similar techniques may be useful for treating such disorders as spinal cord injury, transverse myelitis, amyotrophic lateral sclerosis (ALS), and spinal muscular atrophy. The study was funded in part by the NIH's National Institute of Neurological Disorders and Stroke (NINDS). The researchers, led by Douglas ...

First study to show how immune cells 'speak' to each other in vivo

...s area may ultimately improve treatment for immune disorders such as MS, cancer, and AIDS. WHO: Pedro Lowenstein, M.D., Ph.D., co-director, Board of Governors' Gene Therapy Research Institute, Cedars-Sinai Medical Center and principal investigator of this study, is available for interviews. ...

Hopkins researchers develop new tool to watch real-time chemical activity in cells

...new treatments for heart disease, diabetes, memory disorders and certain cancers, for example. Zhang says the "high throughput" potential of the sensor may have wide-reaching applications that could be adapted to testing various chemicals to test chemicals for their ability to interfere with other enzymes r...

Matrilin-3 gene discovered to prevent onset of osteoarthritis

...-3 have previously been linked to certain skeletal disorders and hand osteoarthritis. But this study, reported ...lin-3 and hand osteoarthritis, as well as skeletal disorders such as multiple epiphyseal dysplasia (MED), a disorder that begins in childhood and can include mal...

Chewing up a key regulator of fat synthesis keeps mice lean despite a high-fat diet

...is good news for the fight against obesity and the disorders characterized by insulin-resistance known as "metabolic syndrome." Most people with insulin resistance will develop type 2 diabetes within 10 years, unless they lose 5 to 7 percent of their body weight--about 10 to 15 pounds for someone weighing 200 ...

Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's

...o nerve cell injury and death in neurodegenerative disorders such as Alzheimer's and Parkinson's Disease. Th...hes for these neurodegenerative diseases and other disorders associated with abnormal protein accumulations due to cellular stress. "To our knowledge, this is ...

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