disorders 2 5

Tag: "disorders" at biology news

Circadian gene helps the brain predict mealtime

...is expected to improve therapies for counteracting disorders that have their roots in a disturbed circadian system, such as sleep problems, eating disorders, obesity, and depression. ...

Study offers window into human behavior, brain disease

... including frontotemporal dementia, and, possibly, disorders such as autism and schizophrenia, the researchers say. In addition, because the disease erodes aspects of social behavior and emotions ?self awareness, moral reasoning and empathy ?that are highly developed in humans, the finding suggests that the...

How many genes does it take to learn? Lessons from sea slugs

... that acts of learning or the progression of brain disorders do not take place in isolation - large clusters of genes within an untold amount of cells contribute to major neural events. "For the first time we provide a genomic dissection of the memory-forming network," said Leonid Moroz, a professor of neu...

Key gene controlling eye lens development identified

...ormation will help us determine what goes wrong in disorders in which the lens does not form, or forms abnormally. That kind of information is often the first step in designing both preventive and treatment strategies for congenital diseases." The St. Jude team further showed that the proteins coded for by...

Crohn's disease gene identified

...lled inflammatory bowel disease (IBD), are chronic disorders that cause abdominal pain, diarrhea and gastrointestinal bleeding and affect over one million Americans. Because IBD tends to run in families and is more frequent in certain ethnic populations, especially Ashkenazi Jews, scientists have long suspecte...

UWM brain research supports drug development from jellyfish protein

...bilities not only deteriorate in neurodegenerative disorders such as Alzheimer's disease, but they also become impaired simply by aging. Aging increases the number of "doors" that allow calcium ions to enter the cells, he said. Moyer, who came to UW-Milwaukee from a post-doctoral position at Yale Univers...

Why we could all do with a siesta

...?have implications for treating obesity and eating disorders as well as understanding levels of consciousness. ...e have a better understanding of what may occur in disorders of sleep and body weight. "This research perhaps sheds light on why our European friends are so fon...

Mutant mice show key autism traits

...(knocking out) a single gene associated with brain disorders in mice. The gene, called Pten, had been associated with a broad array of such disorders when knocked out throughout the animals' bodies. However, Parada and colleagues engineered mice to k...

Newborn screening can cause unnecessary parental stress

.... These "heel stick" tests identify rare metabolic disorders before they cause irreversible damage, but as more disorders are added to the screening ?many states now test for 30 or more ?false-positive results are on the r...

Researchers find protein that silences genes

...s, contributing to tumor growth. And certain blood disorders resulting from defective genes expressed in adults might be alleviated if versions of those same genes that are only expressed very early in development, but are then silenced in adults, could only be turned on again. Though only dreams, at present, ...

Gene linked to rare disease activates fat breakdown

...ations for understanding these increasingly common disorders as well, Zechner said. ...

Drug dials down the energy within cells, UM researchers find

...tive at treating animal models of human autoimmune disorders and other diseases works by dialing down the activity of a key enzyme involved in energy production, University of Michigan researchers have found. "Many drugs block the function of enzymes, essentially turning them off," said Gary Glick, who is the...

Taking the wrinkles out of motoneuronal disease

...he diseases are severe and physically debilitating disorders which lead toprogressive weakness and wasting of muscles. Many of the diseases are incurable. Dr Meunier is developing botox to selectively deliver drugs to motoneurons to directly treatmotorneuron diseases. "I first became interested in investigat...

Mice learn tasks that may help treat human psychiatric disorders

...esearchers find new treatments and cures for human disorders like autism and Parkinson's disease. For the firs...cognitive deficit in mice that is relevant to such disorders in humans, research into new diagnostic methods, treatments and cures is severely hindered," said Jo...

Prion find points way to test for human 'mad cow' disease

...ous proteins responsible for such brain-destroying disorders as bovine spongiform encephalopathy (BSE) in cattle and vCJD in humans--in the blood of the hamsters in as few as 20 days after the animals had been infected. That discovery occurred about three months before the hamsters began showing clinical sympt...

Brain's 'gambling circuitry' identified

...nding and perhaps treating aberrant risk-taking in disorders including gambling addiction, bipolar disorders, and schizophrenia. In their experiments, the researchers asked subjects to choose two cards from a deck numbered one to ten. Before their choice, however, the subjects were asked to bet $1 on whether...

UCLA study finds same genes act differently in males and females

...rch holds important implications for understanding disorders such as diabetes, heart disease and obesity, and identifies targets for the development of gender-specific therapies," said Jake Lusis, Ph.D., co-investigator and UCLA professor of human genetics. The UCLA team examined brain, liver, fat and muscle...

A single sugar found responsible for an antibody's ability to treat inflammation

...ins (known as IgG antibodies) can cause autoimmune disorders like lupus, arthritis and asthma. And yet, when IVIG is infused into people with those exact autoimmune conditions, it calms inflammation rather than causes it. Jeffery Ravetch, Theresa and Eugene M. Lang Professor and head of Rockefeller's Labora...

In drug design, a loose fit may be best bet

...or a host of health problems, from smell and taste disorders to heart disease, asthma, migraine, and pain. The study is published in the May 12, 2006, issue of the "Journal of Biological Chemistry". The researchers looked at thyrotropin-releasing hormone, or TRH, a hormone released in the brain that kicks off...

Speeding the search for elusive chromosomal errors

...agnosis of congenital diseases, including puzzling disorders that lead to mental retardation. "For years, many...6 issue of Human Mutation. For many of these rare disorders caused by small errors in chromosomes, improved diagnosis does not mean that physicians can provide ...

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