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Tag: "disorders" at biology news

New technology to speed up research into Huntington's disease

... cognitive difficulties in other neurodegenerative disorders such as in Alzheimer's and CJD. Huntington's disease is a genetic disease affecting around 8 in 100,000 people. It is characterised by a progressive decline in cognitive functioning (including memory loss, intellectual decline and disorientation) ...

Researchers create mouse lacking key inflammation gene

...or offers a new approach to treating inflammatory disorders along with other immunological conditions. Researc... spearhead discovery of drugs against inflammatory disorders such as arthritis and Crohn's disease. In the study, Boston University researchers created a mous...

'Conversation stoppers' fight deadly bacterial infections

...ent an attractive drug target for a range of human disorders in which disruption of endocannabinoid signaling by cannabinoid receptor antagonists has proven beneficial." ...

Seals protect brain, conserve oxygen by turning off shivering response on icy dives

...ar following cardiac arrest, stroke or respiratory disorders which cause inadequate oxygen supply to the brain, Folkow explained. Folkow will present a second study on hypoxia, involving diving birds, at the conference. The study "Neuronal hypoxic tolerance in diving birds and mammals," examines how diving ...

Nanotechnology propels advances in regenerative medicine research

...ent an attractive drug target for a range of human disorders in which disruption of endocannabinoid signaling by cannabinoid receptor antagonists has proven beneficial." ...

Regulating the nuclear architecture of the cell

... is controlled in the fruit fly can apply to human disorders like birth defects and cancer. The organization of structures in the cell's nucleus has profound effects on such essential functions as how and when genes are expressed. When regulation fails, genome aberrations accumulate, including repeated sequenc...

Brown seaweed contains promising fat fighter, weight reducer

...ent an attractive drug target for a range of human disorders in which disruption of endocannabinoid signaling by cannabinoid receptor antagonists has proven beneficial." ...

Study shows enzyme builds neurotransmitters via newly discovered pathway

...ent an attractive drug target for a range of human disorders in which disruption of endocannabinoid signaling by cannabinoid receptor antagonists has proven beneficial." ...

First biomarker for human sleepiness identified in fruit flies

...ers that will aid diagnosis and treatment of sleep disorders and may one day help assess the risk of falling asleep at the wheel of a car or in other dangerous contexts. "As we prepare for the holiday season and long drives to distant relative's houses, I hope this finding will get people thinking about the...

Novel mechanism of action of new drug for MS identified

...own as eicosanoids. Eicosanoids drive inflammatory disorders such as asthma and multiple sclerosis. According to Sarah Spiegel, Ph.D., professor and chair in the VCU Department of Biochemistry, and lead author on the study, the inhibition of cPLA2 would shut down the entire inflammatory pathway, possibly wi...

Key to acute lung injury lies in Ang2 protein

...crease in Ang2 and cell death can be seen in other disorders such as heart attacks, stroke, eye disease in diabetics and brain tumors. ...

Children of allergy sufferers prone to same problem

...i findings suggest that the potential for allergic disorders in infancy is underemphasized, "even though sensitization to allergens at younger ages has been shown to be more important than sensitization in late childhood for the development of wheezing symptoms and asthma." ...

Amateur boxing linked to brain cell injury

...ospinal fluid levels of these proteins increase in disorders with neuronal and axonal degeneration and damage, and the increase is known to correlate with the size of the brain lesion," the authors write. "When applied to the results of this study, the increases in neurofilament protein and total tau probably...

New tool helps blood specialists improve patient care

...ring performance on the treatment of several blood disorders and cancers. "Participants will be making real-time changes to the way they care for patients. The importance of this experience is invaluable, not only to the physician, but to the patient as well." From applying these measures, physicians will the...

Researchers image molecular motor structural changes

...g of the underlying mechanisms of a range of human disorders such as Down syndrome caused by faulty molecular m...itions, such as Charcot-Marie-Tooth disease. These disorders are thought to be linked to deficiencies in transport by the molecular motors of chemical neurotrans...

Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes

...ncy of further research is underlined by a rise in disorders of the male reproductive tract over the past sever...ncrease is not known, but it is thought that these disorders might be caused by environmental chemicals that are estrogenic and have endocrine-disrupting effects...

Dragonfly's metabolic disease provides clues about human obesity

...ite-infected dragonflies suffer the same metabolic disorders that have led to an epidemic of obesity and type-2...nd in human intestines may play in human metabolic disorders like insulin resistance, type-2 diabetes, and obesity. In mammals, these metabolic disorders are kn...

Researchers discover new gene responsible for brittle bone disease

... "Beyond OI, there may be other connective tissue disorders caused by mutations in genes associated with 3-prolyl hydroxylation, a process that occurs in many types of tissues," Boyce said. "Current treatment for OI does not cure the disease and is designed to reduce the risk of fracture. Only through a bette...

Humpback whales have brain cells also found in humans

...y Alzheimer's disease and other debilitating brain disorders such as autism and schizophrenia. Spindle neurons were also found in the same location in toothed whales with the largest brains, which suggests that they may be related to brain size. The authors note that spindle neurons probably first appeared ...

New biochip helps study living cells, may speed drug development

...d accelerate drug development for muscle and nerve disorders like epilepsy and help create more productive crop...es the new chip could help develop drugs for human disorders involving ion channel malfunction, such as epilepsy and chronic pain. About 15 percent of the drugs ...

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