Vital step in cellular migration described by UCSD medical researchers
...ld lead to therapeutic interventions in autoimmune diseases such as multiple sclerosis and Crohn's disease," said the paper's first author Naoyuki Nishiya, Ph.D., a postgraduate researcher in the lab of senior author Mark Ginsberg, M.D., UCSD professor of medicine. "Since cell migration plays an important rol...Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
...y. But the hormones also increase cancer and other diseases that limit lifespan. The researchers developed a strain of dwarf rats that were naturally deficient in both growth hormone and in IGF-1. To mimic the rise in growth hormone and IGF-1 during adolescence in normal rats, some of these deficient rats we...New SARS Protein Linked To Important Cell Doorway
...on detailed biophysical investigations of emerging diseases months before we can even begin to work with such diseases in culture." Fremont led the initial analysis, which was dedicated to identifying sequences of gene...New studies suggest airborne SARS transmission is possible
...ng to Dr. Yu, "no other known routes of infectious diseases transmission could adequately explain the spread of the disease in the outbreak, and hence we feel that the evidence is quite strong." An editorial accompanying the Toronto study, by Tommy Tong, MBBS, of Princess Margaret Hospital in Hong Kong, emph...Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
...ll transplants as part of therapy for a variety of diseases such as leukemia or sickle cell disease. In these ...s (e.g., acute lymphoblastic leukemia) or red cell diseases (e.g., sickle cell disease). Because blood from the normal, healthy donors contained 1,200 to 155,0...UCLA scientists transform HIV into cancer-seeking missile
...it may be possible to correct acquired and genetic diseases where the mutations exert their harmful effects on the body." Melanoma is a serious form of skin cancer. According to the American Cancer Society, an estimated 59,580 Americans will be diagnosed with melanoma in 2005, and about 7,770 people will die...First real-time view of developing neurons reveals surprises, say Stanford researchers
...ons are required to retain that information. Some diseases also seem to be caused by brain connections not forming normally. Dyslexia, for example, may be caused by connections failing to form between certain brain regions, whereas schizophrenia may result from too many connections forming. What's more, any...Plants defy Mendel's inheritance laws, may prompt textbook changes
...ill be an avenue for gene therapy to treat or cure diseases in both plants and animals." The study is publish...d animals in order to correct mutations that cause diseases and abnormal growth. Though further research is required to learn how this form of inheritance happ...Scientists identify new model Of NK cell development
...ing more effective treatments for cancer and other diseases says Caligiuri. "NK cells are the 'minutemen' of the defense system ?the first to respond to an attack. The more we know about them, the more we can help them do their work. In cancer, as in other diseases, the sooner you intervene, the better." ...White blood cell waste disposal system plays critical regulatory role
...ossible relevance to the treatment of inflammatory diseases and the mitigation of chemotherapy-induced neutropenia," says Dr. Ley. ### Matthew A. Stark, Yuqing Huo, Tracy L. Burcin, Margaret A. Morris, Timothy S. Olson, and Klaus Ley: "Phagocytosis of Apoptotic Neutrophils Regulates Granulopoiesis via IL-23...Agilent Technologies releases automated literature search tool for biology researchers
... focusing on proteomics and metabolomics for these diseases as a complement to Labs collaborators' work in genomics. Using Labs' systems biology informatics prototypes, Labs researchers have built qualitative biological models based on experimental data, scientific knowledge from published papers and curated ...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...ring plan of human cells to more effectively treat diseases while also generating fewer side-effects. "We're basically now able to open the hood of yeast, worm, and fly cells and look at the protein interactions inside," said Trey Ideker, a bioengineering professor at the University of California, San Diego ...Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance
..., rheumatoid arthritis, asthma and dyslexia. These diseases affect a large number of patients worldwide. Syste...cine is all about -- enabling clinicians to detect diseases earlier and manage them more effectively. We are excited about the potential of this agreement to mo...Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
... gene of interest, including therapeutic genes for diseases like cancer and arthritis, to detect where and when they are being expressed," Ahrens said. Existing methods used to image gene expression have limitations, according to Ahrens. Some methods cannot be used in living subjects, fail to image cells dee...Measuring the impact of post-genomics on Mediterranean populations
...ing to alleviate communicable and non-communicable diseases in the region. ...Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss
... The implants are designed for people with retinal diseases such as macular degeneration and retinitis pigmentosa, which cause blindness and vision impairment in about 10 million Americans. More than one million of these people are legally blind. "As is commonly seen in with retinitis pigmentosa, these patie...International HapMap consortium expands mapping effort
...he genetic risk factors underlying a wide range of diseases and conditions," said NHGRI Director Francis S. Co...ealth, such as those protecting against infectious diseases or promoting longevity. "We are excited by the opportunity to apply our technology to all publicly ...Antibiotic might fight HIV-induced neurological problems
... can protect brain cells in animal models of other diseases -- multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer's disease, stroke and more. The drug is being tested in early clinical trials for some non-HIV-related conditions. "Last year we discovered that SIV triggers some of the same biological...Researchers develop rapid diagnostic tool for pathogen identification
...ntial diagnosis. “We focused first on respiratory diseases because differential diagnosis is a common clinical problem with implications for outbreak control and individual case management,?stated W. Ian Lipkin, MD, Jerome L. and Dawn Greene Professor of Epidemiology and professor of Neurology and Pathology ...Ophthalmologists implant five patients with artificial silicon retina microchip
... The implants are designed for people with retinal diseases such as macular degeneration and retinitis pigmentosa, which cause blindness and vision impairment in about 10 million Americans. More than one million of these people are legally blind. "As is commonly seen in with retinitis pigmentosa, these patie...