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Tag: "diseases" at biology news

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

...n would make viral-mediated gene therapy for brain diseases a reality." Dr. Paul Greengard, Nobel Laureate, Vincent Astor Professor and Head of the Laboratory of Molecular and Cellular Neuroscience at Rockefeller University, and Chairman of the Neurologix Scientific Advisory Board, commented, "The initial re...

Nanowires can detect molecular signs of cancer, scientists find

...e especially important in the diagnosis of complex diseases like cancer, for which disease heterogeneity makes tests of single markers inadequate. Patterns of multiple cancer markers might, however, provide the information necessary for robust diagnosis of disease ?[and] detection of markers associated with d...

Discovery of T-cell 'traffic control' boosts new drug promise

...ploiting this approach for treatment of autoimmune diseases and transplant rejection will depend on developing new drugs that block only the immune type of S1P receptor," he adds. "But early studies by a number of researchers are quite promising." Progress will also come from finding "uniquely effective comb...

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

...e AIDS pandemic. Quinn, a professor of infectious diseases at Hopkins and a senior investigator at the National Institute of Allergy and Infectious Disease, reports that women have in the last 20 years moved from being those least affected by HIV to those in whom the disease is spreading fastest. According ...

Quantum dots provide a faster, more sensitive method for detecting respiratory viral infections

...d a doctor who specializes in infectious childhood diseases have joined forces to create an early detection method for a respiratory virus that is the most common cause of hospitalization among children under five. Respiratory syncytial virus (RSV) sends about 120,000 children to the hospital in the United S...

How cell suicide protects plants from infection

...ve cells. Failure of PCD can result in devastating diseases such as cancer, Alzheimer's and AIDS. "This work gives us a better understanding of how plants fend off microbial attacks through carefully controlled destruction of infected cells," said James Anderson, of the Division of Genetics and Developmental...

Device traps, disables harmful bacteria

...ns of Legionella and Mycobacterium, that can cause diseases such as "lifeguard lung." "The results of this study suggest that a reasonable reduction in bioaerosol concentrations can be achieved by installing this new generation of hybrid air filters," the authors conclude. "Engineering control methods must b...

UIC researchers show protein routes messages in nerve cells

...at can manipulate proteins that cause neurological diseases in humans. ...

One bacteria stops another on contact

...r understanding of urinary tract infections. Other diseases may have similar mechanisms, according to the scientists. "This research is in its infancy, but opens the door for exploration of the roles of contact-dependent growth inhibition in urinary tract infections and possibly other diseases," said Low. "A...

Unweaving amyloid fibers to solve prion puzzles

..., the results provide hints as to why mad-cow type diseases tend to have a difficult time jumping species. "These findings give us some fundamental insights in how amyloid fibers form," says Whitehead Member Susan Lindquist, lead scientist in the research team whose results will be published in the June 9 is...

Vineyard weeds found to host Pierce's disease of grapes

...sease of grapes, one of the most destructive plant diseases affecting grapes. Pierce's disease is caused by Xylella fastidiosa, a bacterium transmitted by sharpshooters and spittlebugs. In response to outbreaks of Pierce's disease in central California, plant pathologists studied 29 weed species commonly fou...

Shampoo detergent added to paint makes surfaces self-sterilizing

...logical web for spreading common upper respiratory diseases that cost the U.S. hundreds of billions of dollars annually in lost productivity. While it has long been known that our coinage possesses the quality of being self-sterilizing, little previous thought has been given to making frequently handled surfa...

Muscle repair: Making a good system better, faster; implications for aging, disease

... * PAI-1 levels also appear to be higher in muscle diseases like Duchenne Muscular Dystrophy. In such diseases, muscle repair processes can't keep up with the degeneration caused by the disease. The plasminogen system may represent a therapeutic target for improving muscle function in these instances. * ...

Sugar helps control cell division

..., this process could contribute to cancer or other diseases by failing to properly control the steps and timing of cell division, the researchers say. The findings are described in the Sept. 23 issue of the Journal of Biological Chemistry, available online now. The sugar, known as O-GlcNAc (pronounced oh-GLU...

Visceral Leishmaniasis: Successful Vaccine Trial In Dogs

...s » and 165 « Genetics and evolution of infectious diseases », in conjunction with the Institute of Medical Sciences, Banares Hindu University, Varanasi, India. ...

Huntington's cure in flies lays groundwork for broader treatment approaches

...has long worked in the area of "triplet expansion" diseases such as Huntington's and Fragile X, in which genes...ex realities of humans, Yin says, particularly for diseases that can be attributed to dozens and even hundreds of abnormal gene functions. Yet in some cases, i...

Scientists discover gene that controls speed of tuberculosis development

... to be involved in many other illnesses, including diseases as diverse as leprosy and rheumatoid arthritis. "We discovered that variants (alleles) of the NRAMP1 gene control the speed at which tuberculosis develops, rather than whether or not it will develop at all," says Dr. Schurr. "This is the first time a...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

...nd other non-terminal, debilitating conditions and diseases is both feasible and safe, report researchers who conducted the world's first such test on the approach in patients with advanced rheumatoid arthritis. The results, published in this week's online edition of the Proceedings of the National Academy of...

Tadpole soon to help in the fight against cancer and lymphedema

...any disorders, such as inflammatory and infectious diseases and lymphedema (a swelling caused by water retention). On the other hand, a well-functioning lymphatic vessel network can simplify the spread of cancer cells. A thorough understanding of this network is thus essential for seeking a solution for these...

Genomics researchers discover protein deficit that causes drug toxicity

... structural mechanism that can make drugs for some diseases toxic for some patients. The mechanism decreases a...treat patients with childhood leukemia, autoimmune diseases and organ transplants. The Mayo researchers say their finding advances the field of pharmacogenomics...

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