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Tag: "disease" at biology news

UCLA scientists store materials in cells natural vaults

...ective enzymes, such as those that cause Tay Sachs disease * DNA delivery to correct genetic mutations * Timed release of drugs, enzymes and DNA * Extracting and imprisoning cellular toxins into the vault * Stabilizing proteins in vaults to increase their lifespans AUTHORS: Leonard Rome, pr...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...mic chemotherapy for their recurrent or metastatic disease were enrolled in this study between December 2001 ...ients who received prior chemotherapy for advanced disease did not show a benefit with bevacizumab in combination with capecitabine, a different chemotherapy a...

Secret of smallpox's success may lead to bioterror cure

...w and multiply to the point of causing devastating disease before the immune system detects it and attempts t...viruses not only do not cause disease, but improve disease resistance when they are present. When a mouse has been exposed to a lethal vaccinia virus and then ...

Cellular Defects in Premature Aging Disease are Reversible

...y Hutchinson-Gilford Progeria Syndrome (HGPS) -- a disease associated with premature aging -- can be made hea...closer to understanding this devastating childhood disease and might provide insights into the normal aging process. HGPS is a rare inherited disease affectin...

Disease progression model of pancreatic cancer developed by Penn researchers

...mal model of pancreatic cancer that closely mimics disease progression in humans. From this, they hope to dev...eir findings in the May issue of Cancer Cell. The disease that develops in the Kras and p53 mutant mouse model demonstrates distinct similarities to human pan...

Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma

...cidence of mesothelioma in the world. Rates of the disease have tripled in the past 20 years and are expected to peak about 2010. Diagnosis of this type of cancer is difficult, and patients are often not identified until the condition is quite advanced. Agilent's new microarray techniques in comparative gen...

New polysaccharide may help combat multidrug resistance in cancer

...lso accumulates around the outside of cells during disease processes such as early atherogenesis, persistent ...c, and readily applicable to several proliferative disease processes, especially cancer. We are hoping that hyaluronan antagonists can be used in conjunction w...

Researchers develop assay that could be applied to drug screening

...ted in some types of cancer and neuro-degenerative disease and the protein machinery of CME has been co-opted by several viruses, including rabies, as a means of entry into healthy cells. The researchers led by David Zenisek, assistant professor in the Department of Cellular and Molecular Physiology at Yale...

Gene therapy cures inherited liver disease in rats

...-virus combination cured rats of a inherited liver disease in which lack of a gene causes the accumulation of...Academy of Sciences. "This is the first time this disease (Crigler-Najjar syndrome) has been completely cured long term with a single injection in an adult an...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

...s from umbilical cord blood before symptoms of the disease develop, according to a study published in the May...omatic Leukodystrophy, Tay-Sachs disease, Sandhoff disease and a host of others. "The diseases may be uncommon, but the cost to the child, their family and to...

Stanford gut check shows diversity of intestinal ecosystem

...mmunities vary according to host, diet, geography, disease and other variables. To distinguish individual bacteria among the hundreds of types in the samples, Eckburg took advantage of a technique that compares the genetic sequence of a molecule shared by bacteria and archaea. The molecule, 16S rRNA, plays ...

Stem cell research - new cell lines

...d lead to new treatments for diabetes, Parkinson's disease and spinal cord injury. "This cloning of cells involves a new technique, which is a very accurate way of extracting and then growing a single cell," said UNSW Senior Lecturer Dr Kuldip Sidhu, who is leading the research and is based at the Diabetes ...

Unchecked DNA replication drives earliest steps toward cancer

Although not widely appreciated as a disease of the genes, cancer is always rooted in genetic errors or problems in gene regulation. Scientists have identified some of the first genetic triggers for cancer as mutations in specific oncogenes or tumor suppressor genes. Full-blown tumors and metas...

Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

...tanding gene regulation as it relates to different disease states and a patient's response to drug therapy," said Noel Doheny, Vice President of PreAnalytiX and QIAGEN. "We continue to see a strong market trend towards the correlation of gene expression profiles of whole blood and tissue samples. With the ne...

Two chemicals boost immune cells' ability to fight HIV without gene therapy

...e immune systems of HIV-infected persons fight the disease without invasive gene therapy. Presented March 5 at the 2005 Palm Springs Symposium on HIV/AIDS, the new research demonstrates that the new chemicals activate telomerase -- a protein that boosts immune cells' ability to divide, enabling them to conti...

Breakthrough isolating embryo-quality stem cells from blood

...d repair apparently permanent damage such as heart disease or Parkinson's. The cells are currently taken from aborted human foetuses, an issue which has led to controversy and opposition in many parts of the world. Any alternative source, such as voluntary adult donations, could spark a boom in new cures. S...

Scientists generate patient-specific stem cells, Science study says

... males and females of various ages, suffering from disease or spinal cord injury. The research is being rele.... These cell lines will enable the study of human disease in cells in the laboratory. The work also moves scientists one step closer to the goal of transplant...

SuperLigands - a database of ligand structures derived from the Protein Data Bank

... males and females of various ages, suffering from disease or spinal cord injury. The research is being rele.... These cell lines will enable the study of human disease in cells in the laboratory. The work also moves scientists one step closer to the goal of transplant...

Mouse with designer liver has enhanced glucose tolerance, insulin response

...opment of new drugs for Alzheimer’s disease, heart disease and several forms of cancer. Today the Burnham Institute employs over 700, including more than 550 scientists. The majority of the Institute’s funding derives from federal sources, but private philanthropic support is essential to continuing bold and...

AIDS Public Awareness Campaign Expands Following Report Of Rapidly Progressive HIV

...ercing or tattooing; * Had a sexually transmitted disease (STD); and/or * Have engaged in sex with multiple partners. People who wish to be tested for HIV/AIDS may contact: * New York State HIV/AIDS Hotline - 1-800-541-AIDS * Spanish - 1-800-233-SIDA * Deaf/TDD - 1-800-369-AIDS * New York City HIV/AID...

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