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Tag: "discovery" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...on National Primate Research Center, builds on the discovery made independently by both Harvard and French researchers that a gene called GPR54 is defective in children with a rare disorder that inhibits puberty's onset. To better understand what role GPR54 plays in the initiation of puberty, as well as learn ...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

... activities. The Dana-Farber researchers made the discovery in searching for the function of PGC-1beta co-activator that was isolated in 2002. Experiments including the measurement of gene activity by microarrays showed that saturated and trans fats caused greater activity of the gene that makes PGC-1beta co-...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...n the February issue of the journal, Geology. The discovery of deep sea hot springs and an abundance of microb... life on Earth and a model for the exploration and discovery of life on other planets. "We are highly conscious of the importance of microbes in the grand schem...

UAB scientists discover the origin of a mysterious physical force

...ounds, and when thin films form in detergents. The discovery has been published in today's edition of Physical Review Letters. Water is the solvent in which most physical, chemical and biological processes take place. Therefore, it is essential to understand the nature of interactions between molecules dissol...

Researchers discover way to make cells in the eye sensitive to light

...chester, and one of the paper'sauthors, adds: "The discovery that melanopsin is capable of makingcells photosensitive has given us a unique opportunity to study thecharacteristics of this interesting protein. The textbook view of theeye is that it contains only two light sensing systems, the rods andcones. How...

Protein discovery could unlock the secret to better TB treatment

...chemistry and Molecular Biology at UCL, said: "The discovery of Rpf in the TB bacteria could allow the development of methods to 'wake-up' all dormant bacteria in a patient allowing antibiotics to kill the bacteria and cure the disease." The team includes Prof Brian Henderson at the UCL Eastman Dental Institu...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

...ne National Park use primarily hydrogen forfuel, a discovery University of Colorado at Boulder researchers saybodes well for life in extreme environments on other planets and couldadd to understanding of bacteria inside the human body.A team of CU-Boulder biologists led by Professor Norman Pace, one ofthe worl...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...report. "Both clinically and scientifically, this discovery should expand attention in colon cancer research to earlier events, situations present well before tumors appear," says the study's leader, Andrew Feinberg, M.D., M.P.H., professor of medicine and director of the Center for Epigenetics in Common Huma...

Dysentery uses 'sword and shield' to cause infection

...stroyed by the immune system. Dr Tang adds: "This discovery greatly expands our understanding of how bacteria are sometimes able to evolve although it is unlikely to result in new treatments or vaccines for dysentery. In this case, the dysentery bacteria has evolved into a highly effective and dangerous infec...

New binding target for oncogenic viral protein

... Fred Hutchinson Cancer Research Center report the discovery of an additional target for T antigen--a protein called Fbw7. The Fbw7 gene is located in a chromosomal region that is deleted in up to 30% of human tumors. "Fbw7 is itself an important tumor suppressor which makes it an attractive choice for inacti...

Controversial drug shown to act on brain protein to cut alcohol use

...ing and consumption was significantly reduced."The discovery that Ibogaine reduced binge drinking after a period ofabstinence was an exciting finding for us because this is the type ofbehavior in alcoholics for which very few effective drugs exist," Janaksaid.The scientists confirmed in a cell model that Iboga...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

... Says Petri: "The genome project has spawned rapid discovery of the parasite's mechanisms for replication, gene expression, motility, metabolism, and the killing of host cells." ### The Institute for Genomic Research (TIGR) is a not-for-profit research institute based in Rockville, Maryland. TIGR, which sequ...

Scientists detect probable genetic cause of some Parkinson's disease cases

...auseof Parkinson's disease identified to date. The discovery by aninternational research team provides fresh evidence that genetics maycontribute to the development of some cases of Parkinson's disease. Thefindings could lead to the development of a genetic test to detect themutation in individuals at risk. Th...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

...nneth McIntosh of Harvard Universitycommented that discovery of a new human respiratory coronavirus wouldnot be surprising, since studies in the 1960s and 1970s had pointed toa number of novel coronavirus strains but the findings were notadequately followed up because methods to do so were unavailable at theti...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...sin, Madison, the Mayo Clinic researchers made the discovery about a class of prescription drugs known as "HIV protease inhibitors." Drugs in this class go by the generic names of lopinavir, nelfinavir, indinavir, ritonavir and saquinavir. Brand names include Kaletra, Viracept, Crixivan, Norvir and Fortovase. ...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...her for acommon cause."What would open-source drug discovery look like? "As with currentsoftware collaborations..."The key to TDI's success, they argue, is that any discovery would beoff patent. An open-source license would keep all discoveries freelyavailable to researchers...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...rmacology and Cancer Biology at Duke.He said their discovery could aid in the diagnosis and ultimately thetreatment of serious disorders caused by low iron levels.Results of his study, funded by the National Institutes of Health, arepublished in the Jan. 14, 2005, issue of the journal Cell. Iron deficiency is...

Learning to fight an adversary that won't stay down

... of dollars into 'modern' approaches to antibiotic discovery over the past six or seven years and this has failed miserably." The scientist, whose work is supported by Science and Engineering Research Canada (NSERC), has organized a symposium on the evolutionary genetics of antibiotic resistance at the 2005 m...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

...hey make the toxinappropriately.?Gilmore says this discovery has several significant implications forthe future... with loss of vision,?says Gilmore.“Secondly, this discovery will help us to develop new ways to treatinfections that are resistant to antibiotics, making them l...

Sea skate experiment sheds light on human cell transport

...ther organic material. The researchers made their discovery by using a plant-based substance to block an enzyme that causes phosphorylation. The result: The gates wouldn't open. These findings are published in the current issue of the American Journal of Physiology: Regulatory, Integrative and Comparative Phy...

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