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Tag: "discover" at biology news

Tissue regeneration operates differently than expected

Max Planck researchers in Bad Nauheim discover the mechanism by which adult stem cells are integrated into skeletal or heart muscle tissue. There is disagreement, however, about the mechanism on which repair processes are based. Scientists from the Max Planck Institute for Heart and Lung Research...

UNC scientists discover new role for protein as fundamental inhibitor of cell movement

...body. "I was ecstatic to see these results and to discover that it also regulates the fundamental process of cell migration," said Dr. Tina Leisner, associate professor of pharmacology at UNC and the study's lead author. "CIB1 plays a prominent role in the activation of PAK1 and potentially may be another im...

Rutgers to lead $52.7 million protein research program

...tures have given us new insights and allowed us to discover the functions of proteins that weren't recognized before," said Montelione, a professor of molecular biology and biochemistry at Rutgers and a resident faculty member of the Center for Advanced Biotechnology and Medicine (CABM), a research institute ...

Evolution of life on Earth may hold key to finding life in outer space

...machinery is very, very old," Fox said. "If we can discover the earliest aspects, then scientists may be able to devise experiments to see how simple RNAs might have given rise to this machinery. This information would help us to better understand how life evolved on Earth and how ribosomes actually work, whi...

Researchers create functioning artificial proteins using nature's rules

...way to make artificial proteins in the lab, but to discover the rules that nature and evolution have used to design proteins," Dr. Ranganathan said. "The rules we have extracted from the evolutionary record of proteins contain a substantial fraction of the information required to rebuild modern-day proteins. ...

New technique helps identify multiple DNA regulatory sites

...od testing, and thus greatly accelerate efforts to discover the origins of disease. The demand for ever-shrin...'s genetic code. Scientists use DNA microarrays to discover and analyze a person's DNA or messenger-RNA genetic code. This allows for, say, the early diagnosis ...

New technique may speed DNA analysis

...od testing, and thus greatly accelerate efforts to discover the origins of disease. The demand for ever-shrin...'s genetic code. Scientists use DNA microarrays to discover and analyze a person's DNA or messenger-RNA genetic code. This allows for, say, the early diagnosis ...

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

...ughest challenges facing researchers attempting to discover how life works. "Binding sites," or areas of DNA that interact with the proteins that help control gene expression, can be a long distance on the DNA strand from the genes they influence. Recent research also has shown that gene expression can be con...

Team of international scientists departs today to discover the unknown in China's Himalayan region

In the quest to discover new species, a team of international scientists leaves today on a month-long expedition to explore the undiscovered treasures in the Mountains of Southwest China, an extension of the great Himalayan mountain range. "Expedition Everest: Mission Hima...

Beyond genes: Lipid helps cell wall protein fold into proper shape

...nce of PE. The team is using the E. coli model to discover how all proteins fold in the membrane, not just transport proteins such as GabP but also biosynthetic proteins that manufacture complex compounds such as proteins and fats out of simple compounds. "The next goal now that we've defined the phenomenon...

Malfunctioning bone marrow cells sabotage nerve cells in diabetes

...ns. "In our latest studies, we were surprised to discover that insulin-producing cells originating from bone marrow caused premature cell death and dysfunction when they merged with neurons, resulting in neuropathy," said Chan. "It all began several years ago, when we were developing gene therapy to cure...

Scientists devise way to measure RNA synthesis on the fly in a live cell

...ational Academy of Sciences, could help scientists discover new drugs and learn to what extent some RNA molecules help control the blueprint of life. "The standard assumption has been that DNA encoding for proteins was the sole actor to control the blueprint for all of life," said Philippe Cluzel, an Assista...

NIH renews network focused on how genes influence drug responses

...hythmia Therapy --$14 million provided by NHLBI to discover the common DNA variants that determine why drugs used to treat potentially fatal irregular heartbeats (arrhythmias) are beneficial to some people and harmful to others. (Dan M. Roden, M.D., Vanderbilt University) The Amish Pharmacogenomics of A...

Biased reporting found in cancer prognostic studies

...itute. In recent years, researchers have raced to discover and publish papers on prognostic factors for cancer and other diseases. For example, at least 116 published studies alone have focused on a single tumor suppressor protein (TP53) that may predict the outcome of a patient with head and neck cancer. As...

Novel mechanism for DNA replication discovered

...ount Sinai School of Medicine researchers first to discover that a protein can provide the coding information for DNA replicationSince the discovery of the structure of DNA by James Watson and Francis Crick in 1953, the paradigm for DNA replication has stated that the DNA itself codes for the appropriate pair...

Space matters: Estimating species diversity in the fossil record

... Edward Davis are able to test this assumption and discover that the golden rule of ecology holds for the rock record as well. Just as geographic sampling influences diversity counts in the modern landscape, the species-area effect strongly influences counts in the fossil record. Taking this into account will...

Snapin: A protein with therapy potential for autism

...ith specific disorders and Firestein's quest is to discover how these dissimilar patterns come about and why. A new paper by Firestein and her colleagues at Rutgers, The State University of New Jersey, examines the role of the protein snapin in nerve branch, or dendrite, patterning and its potential as a dru...

Compound might defeat African sleeping sickness, clinical trial beginning this month

...e of the models for public-private partnerships to discover and develop drugs for poorer countries or neglected diseases, Tidwell said. "We have been able to reduce the cost of drug discovery to a fraction of the cost it would take a large drug company to do it, but we're not cutting corners, and we're using...

Genomic sequences processed in minutes, rather than weeks

...rs to understand the body's cellular machinery and discover clues to some types of cancer. And it will help in developing drugs or detection methods to be used for particular diseases," said T.P. Straatsma, a PNNL senior research scientist. And it likely will help in other areas of human health. "It's fair t...

How monarch butterflies are wired for navigation

...avigation. Also, the researchers were surprised to discover a key wiring connection between the light-detectin...um. Using tracer molecules, they were surprised to discover tiny neural fibers containing a key clock protein that connected with the polarization photoreceptor...

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