'Virus chip' detects new virus in prostate tumors
... validates the strategy of using the virus chip to discover previously unknown viruses and potentially uncover new viral causes for disease, the researchers say. While most other virus identification techniques require researchers to look for only a small number of candidates, the virus chip represents an unb...Common molecular 'signature' identified in solid tumors
... Ohio State University and the first researcher to discover miRNA involvement in human cancer, had a hunch that there might be shared patterns of miRNA among certain cancers. Under his direction, researchers looked for miRNA activity, or expression, in 540 samples of lung, breast, stomach, prostate, colon and...Infant transplant patients resist infections that kill adult AIDS patients
...an immune system -- and hopefully, in the process, discover new treatments for debilitating diseases," says Dr. Platt. ...Why the Amazon rainforest is so rich in species
...he ecology and biology of each species. We want to discover more about why some species survive and multiply, while others remain static or become extinct." Around 40% of the world's species can be found in the tropical areas of south and central America. Scientists have long believed that the wealth of spec...A salty tale: New bacterial genome sequenced from ancient salterns
...ut life in the ponds, scientists were surprised to discover ordinary bacteria also thriving in such a physically demanding environment, at salt concentrations up to 30 percent. How could these microbes--which normally prefer milder environments--thrive in such high salt? To find out, TIGR researchers Emmanu...Gene variation affects tamoxifen's benefit for breast cancer
...omprehensive Cancer Center were among the group to discover CYP2D6 metabolizes tamoxifen, and they are leading ongoing work looking at how genetic differences affect women's response to tamoxifen. Their research has also found the antidepressant drug Paxil can prevent tamoxifen from being activated, while the...Finding rewrites the evolutionary history of the origin of potatoes
...oes and researching them. "When researchers discover an important trait - for example, that a certain species is resistant to disease - then everything related to that species becomes potentially useful," Spooner says. "We can screen samples to see if related germplasm has similar resistance, in which...Mining biotech's data mother lode
... them. Microarrays process thousands of samples to discover what genes are over expressing. These over-express...too ?create proteins. The researchers then need to discover what protein interactions are taking place among all the different proteins created by the over-expr...Scientists pinpoint inflammation gene
...aceuticals to conduct laboratory investigations to discover the function of the SEPS1 gene and this particular variant. "These experiments showed that this genetic variation affects how the cell responds to stress," Curran said. "The more common variant the one most people have is the 'good form' of SEPS1...New class of antibiotics effective against drug-resistant bacteria discovered in fungi
... Tech, carried out field and laboratory studies to discover the fate of arsenic fed to poultry. She and her graduate students found that bacteria in the litter and in shallow subsurface soil transform organic arsenic to inorganic arsenic. Organic arsenic is not highly toxic to humans, but inorganic arsenic, w...Geoscientists follow arsenic from chicken feed to streambeds
... Tech, carried out field and laboratory studies to discover the fate of arsenic fed to poultry. She and her graduate students found that bacteria in the litter and in shallow subsurface soil transform organic arsenic to inorganic arsenic. Organic arsenic is not highly toxic to humans, but inorganic arsenic, w...Seaweed yields new compounds with pharmaceutical potential
...the lead author on the paper. "The next step is to discover how these compounds work and then to study them in a more complex model system." The U.S. pharmaceutical company Bristol Myers Squibb is collaborating with Georgia Tech researchers to determine how some of these 10 compounds kill cancer cells. Mean...Researchers discover why melanoma is so malignant
...act, Gupta points out that occasionally physicians discover that perfectly benign melanocytes will sometimes manage to migrate through a patient's body into, say, the lymph nodes. This phenomenon isn't related to cancer, but rather demonstrates the latent ability of melanocytes to travel Finally, the researc...The earliest animals had human-like genes
...g species like insects have lost most of them. To discover what early animals were like, scientists usually compare their descendents. This is difficult when comparing distantly-related animals such as humans and flies. In these cases, it helps to look at living organisms that have preserved many features of...UT Southwestern researchers develop screening test for cells that activate immune system
...hima said he hopes to garner additional funding to discover potent immuno-stimulatory drugs by screening high-quality libraries of compounds. Doing so may be the first step toward developing a new class of vaccines that force or trick the natural immune system to kick on, or initiate an immune response tha...Amphetamines reverse Parkinson's disease symptoms in mice
...rkinson's disease," said Caron. "We may be able to discover avenues for treatment that had never been thought about before or that were impossible to investigate." The new mouse model enables the researchers to acutely eliminate dopamine, exposing systems contributing to the disease that may not have been ob...Scientists unpick genetics of first 15 minutes of life
...chers use the fruit fly Drosophila melanogaster to discover the basic genetic processes of sex, the same genetic processes are present in all sexually reproducing animals, including humans. "All sexually reproducing animals do the same kind of DNA 'dance' when the DNA from the mother's egg cell and the fathe...UF scientist finds unexpected link between cat and human AIDS viruses
...r vaccine." Yamamoto's team was also surprised to discover that a core protein found in HIV also effectively protects cats against FIV. "So what does this mean to human AIDS research? The viruses HIV and FIV are from the same viral family," Yamamoto said. "For that reason, the amino acids that make up the p......r of food have led Purdue University scientists to discover the molecular machinery that enables the pathogen to blast its way into rice plants. The fungus, Magnaporthe grisea, which is known as rice blast fungus, is the most deadly of the pathogens that attack rice, reducing yields by as much as 75 percent ......hape, but it jiggles," explains Graves. "We didn't discover jiggling, but we were able to determine that the amount of internal motion within a protein corresponds to the ability of a protein to do its work." Phosphorylation was found to decrease the internal motion of Ets-1, reducing its activity. According...