New insight into machinery of immune cells' 'tentacles'
...r studies, Pendergast and her colleagues sought to discover the signaling proteins in T cells responsible for formation, or polymerization, of the protein actin into filaments following activation of the T cells. Such actin filament formation is crucial for the T cell to attach to APCs, called B cells, which ...Major WHO study concludes calcium supplements can reduce complications during pregnancy
...ung-Hsin Lin of National Taiwan University hope to discover and develop real compounds that can regulate flap motion in this manner. Lin is currently assembling a team of researchers for this project. In the meantime, while Perryman is completing a postdoctoral fellowship, he is learning about protein enginee...Computer simulation hints at new HIV drug target
...ung-Hsin Lin of National Taiwan University hope to discover and develop real compounds that can regulate flap motion in this manner. Lin is currently assembling a team of researchers for this project. In the meantime, while Perryman is completing a postdoctoral fellowship, he is learning about protein enginee...A new way of looking at molecular motors
...t functions," explained Soldati. "We will have to discover the myosins' functions one by one, and the better we understand how they are related, the faster that will occur." The new classification system also describes common evolutionary links between subclasses and protein components within myosins themse......roving our understanding at this level that we can discover how to maintain the health of ecosystems at a global level." ...The giant protein titin helps build muscles
...s and structural biology, and it gives us a way to discover why some mutations in titin are linked to diseases," says Gautel. ...Rice University researchers create 'nanorice'
...archers in the Atamna laboratory were surprised to discover it was a peroxidase--a type of enzyme that reacts harmfully with biological materials essential for proper brain function such as serotonin and L-DOPA. Dr. Atamna believes that the combination of functional heme deficiency, which harms mitochondria n...Supersized 'island' of resistance genes discovered in an infectious bacterium
...vered new resistance genes. "We were surprised to discover 19 new resistance genes that escaped the scrutiny of the large number of laboratories already working on multi-drug resistant A. baumannii throughout the world. This is a demonstration of the efficiency of the whole genome approach in characterizing...Alzheimer's study first to explain death of brain cells
...archers in the Atamna laboratory were surprised to discover it was a peroxidase--a type of enzyme that reacts harmfully with biological materials essential for proper brain function such as serotonin and L-DOPA. Dr. Atamna believes that the combination of functional heme deficiency, which harms mitochondria n...MiRNA fingerprint identified in platelet formation
...'s Human Cancer Genetics Program, was the first to discover a link between miRNA and cancer. In the current study, Croce, who is also a member of the OSU Comprehensive Cancer Center, along with Garzon and colleagues from the M.D. Anderson Cancer Center, examined miRNA activity in the earliest phases of platel...Neuroscientists discover new cell type that may help brain maintain memories of smells
...photon microscopy to overcome these hurdles and to discover that Blanes cells talk to granule cells. "The multiphoton microscope allowed me to identify the axon and then follow it for long distances without damaging the Blanes cell. Once I could follow the axon as it coursed through the brain, it was rela...Researchers test new way to quit smoking
...gely untested ideas. The aim of our research is to discover if there is a measurable difference in quitting success rates between the two groups in our trial," said Dr Bullen. ...Aggression-related gene weakens brain's impulse control circuits
...ildren. Meyer-Lindenberg and colleagues set out to discover how this works at the level of brain circuitry. Using structural MRI in 97 subjects, they found that those with L showed reductions in gray matter (neurons and their connections) of about 8 percent in brain structures of a mood-regulating circuit (...Stanford study of owls finds link in brain between sight and sound
... decreases signaling," Winkowski said. "We want to discover the cellular mechanisms of how attention works." "Once we learn the circuitry for attention, we plan to use that to drive learning in an efficient way," said Knudsen. He added that they eventually hope to show that they can make adjustments in the c...Ticks, flukes, and genomics: Emerging pathogens revealed
... put ehrlichiosis under the genomic spotlight--and discover some brilliant biology. Led by scientists at The Institute for Genomic Research (TIGR) and The Ohio State University (OSU), a team of researchers report the complete genomes of three emerging pathogens that cause ehrlichiosis-- Anaplasma phagocytop...Discovery of new molecular tools for biosynthesis could lead to advances in use of pectin
...from the use of biochemistry and bioinformatics to discover gene sequences, could be genetically altered pectins that might dramatically improve plant species' ability to fight disease and new pectins that could be specifically targeted to fight cancers in humans. (It has also been demonstrated that pectin lo...Researchers get neurons and silicon talking
...to test the effect of drugs on neurons, to quickly discover promising avenues of research," says Professor Stefano Vassanelli, a molecular biologist with the University of Padua in Italy, and one of the partners in the NACHIP project, funded under the European Commission's Future and Emerging Technologies ini...Powerful new tool for studying brain development
...hers. They say the map will likely help scientists discover the genetic origins of brain cancers, which could speed development of novel drugs to treat them. The continual updating and completion of the BGEM Web site will be crucial to scientists. More than half of the approximately 25,000 genes in the mouse...MIT chemist discovers secret behind nature's medicines
...lized SyrB2 and then used X-ray crystallography to discover the physical structure of the protein. The X-rays scatter off the crystal, creating patterns that can be reconstructed as a three-dimensional model for study. Normally, iron-containing enzymes have three amino acids that hold the iron in the active ......d disease. "We have an important new tool to help discover molecules that can enhance or block different kinds of tastes," explains principle investigator Nancy Rawson, PhD, a cellular biologist. "In addition, the success of this technique may provide hope for people who have lost their sense of taste due to...