Genes and biomarkers that allow doctors to choose the right therapy for the right patient
...e," Dr. Diaz said. Cellular pharmacogenomic to discover genetic determinants of Tykerb response: Abstract...tic targets in human head and neck cancer cells to discover specific genes that might shade an individual’s response to Tykerb. "Our goal is to apply advance...Racing neurons control whether we stop or go
... also shows how mathematical models can be used to discover how the brain produces thought and action." Vanderbilt psychologists Leanne Boucher, Thomas Palmeri, Gordon Logan and Schall published the findings in the April issue of Psychological Review. The new paper uses physiological data collected in ...Cancer researchers add spice to research against rare neuromuscular disease
...one the androgen receptor, and he was the first to discover that the protein needs molecular allies called co-factors to accomplish many of its tasks. Now more than 70 co-factors are known, offering many new targets to potentially stop conditions like Kennedy's disease that involve the receptor itself. Cha...Largest genomic search finds genes that may contribute to autism
...also was announced today to continue the effort to discover the genes that cause the disorder. This $14.5 million phase is being funded by Autism Speaks, the British Medical Research Council, the Health Research Board of Ireland, Genome Canada and its partners, Canadian Institutes for Health Research, Southw...Cracking open the black box of autoimmune disease
...autoimmunity is a black box," says Young. "When we discover the molecular mechanisms that drive these conditions, we can migrate from treating symptoms to developing treatments for the disease itself."...New hereditary breast cancer gene discovered
...ome should be receive early mammograms in order to discover breast cancer at an early stage. "We have already started to use this new knowledge in our work with patients and now recommend regular mammograms for young women with this syndrome. Several early cases of breast cancer have already been uncovere...Scientists reveal structure of gateways to gene control
... edges of nucleosomes," Pugh said. "We might even discover some sites that regulate genes that we didn't even know existed." ...New UD technology removes viruses from drinking water
...ems. "There are lots of exciting things you can discover working together," Jin said, smiling. "In this project, we all need each other. Pei is the engineer and knows where we should put this step and how to scale it up. I study how viruses and other types of colloidal particles are transported in water, a...ASU researchers test antibacterial effects of healing clays
... don't understand yet," Williams says. "What if we discover a mechanism for controlling microbes that had never been discovered before? It is these avenues, at the boundaries of scientific discovery, at the edges of my field and knowledge (and Shelley's), where such discoveries are made." National Institut...Key to zebrafish heart regeneration uncovered
... injury. Future studies in zebrafish could help us discover why this regenerative ability is lacking in mammals and potential ways to stimulate it." ...Backache beaten by good vibrations?
...only known as sciatica ?in the first ever study to discover if therapeutic ultrasound can help their condition. Dr Christopher McCarthy and his team at the University's Centre for Rehabilitation Science need 30 volunteers aged 22-55 who have had sciatica for less than 12 weeks, are not pregnant and have not ...New study aims to stop sepsis in its tracks
...h the different interventions, the scientists will discover whether the factors can serve as molecular markers to help track organ function and recovery progress in patients. This molecular approach may also shed light on new ways to understand and treat sepsis. And consortium researchers will study the cos...Novel experiment documents evolution of genome in near-real time
... discovery and analysis, and could even be used to discover bacterial capabilities that would benefit humankind in a variety of ways," said Herring. "There may be a number of biotech companies that want to use this new approach to help design bacteria to do useful jobs." UCSD's office of Technology Transfer...With fruit fly sex, researchers find mind-body connection
...man behavior. For example, McKeown recently helped discover a genetic mutation that causes flies to develop symptoms similar to Alzheimer's disease ?a gene very similar to one found in humans. Some of McKeown's recent work focuses on understanding gene networks that control sexual behavior. Research on the...Stem cells engage in dialogue with the cells that regulate their futures
... been known for a long time, what's been harder to discover are the characteristics of the cells making up these niches and how they make it possible for stem cells to do their job. Signaling between cells in the niche plays a role in stem-cell upkeep and development. Most research has focused on the signalin...Studies look at how genes affect antipsychotic drug response
...s at Chicago College of Pharmacy are attempting to discover how genes determine how well an antipsychotic medication works in adults and children and the side effects it will cause. Risperidone, a popular "atypical" antipsychotic medication, is used to treat mental illnesses such as schizophrenia and bipolar...Selecting life: Scientists find new way to search for origin of life
... locating the remaining adsorbed molecules. To discover "which molecules stick and which don't," as Hazen says, the Carnegie scientists are also collaborating with a team at the Smithsonian Institution led by Edward Vicenzi to employ a workhorse of chemistry called Time-of-Flight Secondary Ion Mass Spectr...Study illuminates how the plague bacteria causes disease
...rec Stebbins of Rockefeller University. "If we can discover which ones are critical, we might identify the pathogen's Achilles heel--an attractive target for antibacterial or anti-virulence compounds." "We were quite excited to see such a critical and unexpected factor in the virulence of Yersinia--a bacter...Successful lung cancer surgery not enough to break nicotine dependence in many smokers
...e ability to quit, and they also were surprised to discover that higher education was associated with a greater likelihood of smoking after surgery. "It wasn’t the number of cigarettes smoked daily that determined who couldn’t quit, but how long they continued to smoke before surgery. About half of the patie...Does missing gene point to nocturnal existence for early mammals?
... of them to be lost in mammals. "We are keen to discover why this might have happened ?perhaps the early mammals were at one stage nocturnal and had no need for the second gene, for instance. We also want to find out what losing one of these genes means for humans."...