UW scientists report a new method to speed bird flu vaccine production
...he lab-made virus - whose genes are manipulated to disarm its virulent nature - can be seeded into chicken eggs to generate the vaccine used in inoculations, which prepare the human immune system to recognize and defeat the wild viruses that spread among humans in an epidemic or pandemic. In their report,...New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus
... Therapies against a new flu strain would need to disarm the parts of the virus that do the most damage to the body. In order to learn which components of the virus would be the best targets for such therapies, Terrence Tumpey of the Centers for Disease Control and Prevention and his colleagues revisited t...Flesh-eating bacteria escape body's safety net
...gy to inhibit the Strep DNA-degrading enzyme could disarm the pathogen, making it susceptible to clearance by our normal immune defenses," he said. ...USC team reveals structure of APOBEC family protein
...c disease-causing agent. Others have been shown to disarm viruses like HIV and hepatitis B. Uncontrolled, of course, the APOBEC proteins could create havoc in a cell. But normally, under the cell's tight regulation, "these are the good guys," Chen said. When Courtney Prochnow, a graduate student in C...Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease
...viruses, including HIV, use a similar mechanism to disarm their victims," said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal. "The Columbia study has shown us new ways to fight against deadly viruses the world over." The method for discovering this protein underscores the power of bioinforma...Research holds promise for herpes vaccine
...long before disease can occur. "In short, we can disarm the virus such that it is absolutely unable to cause disease, but is still remarkably potent as a vaccine," Halford said. In a human vaccine, the genetic instructions for ICP0 would actually be removed, creating an "attenuated," or weakened virus......., they knock down the front door of resistance and disarm the cell's alarm system. Now, researchers at the University of California, San Diego (UCSD) School of Medicine have identified a novel molecular target for an effector protein called YpkA, one of several effectors of the bacteria Yersinia – the path...