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Tag: "disabling" at biology news

Cells re-energize to come back from the brink of death

...how abnormal cells that have cheated death once by disabling the main suicide pathway called apoptosis can also foil a backup self-destruct program, which allows them to survive and become cancerous. The St. Jude study also suggests that a drug that disrupts a cancer cell’s ability to block this backup pro...

Research team identifies new Alzheimer's gene

...n. Alzheimer’s disease is the most common form of disabling memory and thinking problems in older people. The progressive neurological disorder afflicts an estimated 5 million Americans, a number expected to triple by 2050. “We have entered a new era in medical research. Today’s technologies permit us to ...

Breakthrough developments in rheumatoid arthritis reported

...ure out what makes these people susceptible to the disabling inflammatory condition. Dr. Gregersen has finally closed the circle between key genes identified in his laboratory at the Robert S. Boas Center for Genomics and Human Genetics at The Feinstein Institute for Medical Research in Manhasset, NY and mor...

How plague-causing bacteria disarm host defense

...ers speculate that YpkA plays an important role in disabling the body's immune system beyond its previously known role of disrupting the host cell's normal structure, which interferes with the cell's innate ability to engulf and destroy invading bacteria. "The question now becomes, why is Gaq targeted by YpkA...

Gene thought to assist chemo may help cancer thrive

...s in cell cultures and mice. If it bears out, then disabling the gene in tumors, through medications or new genetic techniques during chemotherapy may help patients survive....

Carnegie Mellon University research shows how sensory-deprived brain compensates

...g sight, hearing, taste, smell or touch are common disabling side effects of traumatic brain injury and stroke. In her study, Barth recorded brain activity in mice with various degrees of whisker removal. As a first step in her research, Barth removed all but one whisker and recorded neural activity in a br...

Prenatal cocaine's lasting cellular effects

... cocaine use during pregnancy can cause subtle but disabling cognitive impairments -- attention deficits, learning disabilities and emotional problems. A recent study by investigators at the Vanderbilt Kennedy Center for Research on Human Development may help explain the long-term behavioral and neurological...

Scientists identify specific enzymes that make meningitis hard to fight

...in the bloodstream. In theory, finding some way of disabling these enzymes would render the bacteria unable to repair itself, and therefore vulnerable to attack and defeat by the body's immune system."...

Virginia Tech's System X supercomputer provides super tool for simulation of cell division

... traits of 130 mutant yeast strains constructed by disabling and/or over-expressing the genes that encode the proteins of the regulatory network. The model has 143 parameters that need to be estimated from the data. "That is a big problem," said Watson. "You can't do that by hand. You can't even do it on a lap...

Backache beaten by good vibrations?

...thy explains: "Sciatica is an extremely common and disabling condition treated by physiotherapists. "The pain caused by inflammation of lumbar nerve roots could potentially be reduced with the application of TU, a form of electrotherapy commonly used by physiotherapists to accelerate the resolution of the i...

New technology to speed up research into Huntington's disease

...ients, the cognitive and emotional symptoms are as disabling as the more obvious motor effects of the disease, and much effort is focused on understanding cognitive decline in HD". "Useful cognitive testing has been a bottle-neck in developing new treatments for this aspect of HD. The touchscreen system s...

Scientists discover toxin that causes gastro disease

...component of the cell machinery in half, therefore disabling it," he said. As well as learning how the toxin works, the scientists have also determined its three-dimensional structure, which will aid in the development of treatments for toxin-related diseases. "This toxin belongs to the family of toxin...

Inflammation markers identify fatigue in breast cancer survivors

...os Angeles have defined conditions associated with disabling fatigue that persists for years in almost a third of breast cancer survivors, according to a study in the May 1 issue of Clinical Cancer Research. The key to their fatigue stems from responses within their immune systems. "These studies identif...

Tests for 'face-blindness' reveal disorder may not be so rare

...ped diagnostic tests for prosopagnosia, a socially disabling inability to recognize or distinguish faces. They've already used the new test and a related web site ( www.faceblind.org ) to identify hundreds of "face-blind" individuals, far more than scientists had identified previously. The researchers, led b...

Reversing 'hibernating' heart muscle focus of UB researchers

...ion called "hibernating myocardium" that can cause disabling heart failure and sudden death. Hibernating myocardium is a condition in which myocytes (cells in the heart's muscular tissue) shut down, but remain viable in areas that receive reduced blood flow over an extended period of time due to narrowed ar...

Scientists tie several cancers to common 'oncogene engine'

...by showing that when tumors in mice were shrunk by disabling one of the transcription factors, replacing it with another member of the family re-started the tumor's growth.In the short term, clinicians will attempt to exploit this interconnectedness by using therapies that may be effective against one tumor to...

Wild meerkats school their young

...e item and return it to the pup, sometimes further disabling it before returning it to the young meerkat. The researchers, Alex Thornton and Katherine McAuliffe, Department of Zoology, University of Cambridge, are part of the Kalahari Meerkat Project, located at the Kuruman River Reserve, South Africa. The ...

BGSU biologist trying to crack microscopic code

...nowing how they communicate would provide a key to disabling it, Larsen says. Once communication questions are answered, a goal is to develop drugs to break the barrier, rendering the bacteria more susceptible to the human body's natural defenses--antibodies--as well as certain antibiotics, he points out. ...

Tumor cells that border normal tissue are told to leave

...ent their metastatic behavior. They have seen that disabling some of the genes in the pathway activated in boundary cells stops the cells from leaving the tumor. Cagan's laboratory also has developed a robotic system for screening anticancer drugs, and they plan to use this system to look for drugs that will ...

Multi-million pound UK Biobank underway

...ople who are at risk of developing a wide range of disabling and life-threatening conditions over the new few decades. So, following them through their health records will allow researchers to work out why some develop a particular disease, while others do not. This should help enormously in the development of...

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