Breakthrough in micro-device fabrication combines biology and synthetic chemistry
...pital equipment intensive) and not well-suited for directly producing large numbers of complex, three-dimensional, nanostructured devices with a wide variety of chemistries and properties. Nature, on the other hand, provides spectacular examples of micro-organisms that synthesize microscopic nanostructured s...Virginia Tech, Nanjing Institute researchers discover half-billion year-old fossils
... Ediacara fossils from China. Their discovery thus directly confirms Seilacher's hypothesis. The new fossils also help to refine the Seilacher hypothesis. Seilacher originally hypothesized that Ediacara tubes had closed ends and were filled with cytoplasm, or cell contents. The fossils from China, however, a...Scientists discover gene that controls speed of tuberculosis development
...ghs to be developed into treatments and cures that directly benefit patients." ...Nanoscale method for investigating living systems
...chnology that until now could be theorized but not directly observed. "To get a feeling of why this is important, you have to understand that each of our cell membranes has specific pores in them that regulate the flow of ions in and out," says Blick. "Through these ions, your cells will build up electric po...Columbia scientists develop cancer terminator viruses
...tases). As predicted, when the virus was injected directly into the primary tumor, the virus destroyed not only the primary tumor, but also distant tumors. While the infection caused by the virus was sufficient to kill the primary tumor, a second weapon added to the virus �V interferon-gamma (IFN-��) �V eli...Results of world's first gene therapy trial for arthritis show approach safe, feasible
...more direct in vivo approach ?introducing the gene directly to affected tissue ?using as the vector an adeno-associated virus (AAV) instead of the vector used in the trial reported in PNAS. AAV appears to have a good safety profile and, in animals, facilitates more extended gene expression. The investigators ......s found that the ventral part of the SCN, which is directly connected by a nerve to the light-sensing retina, synchronizes rapidly with a new light schedule, even a radically shifted schedule. But the dorsal part of the clock requires several additional days to adjust. This results in complex signaling patter...Identical twins may have more differences than meet the eye
...fers to chemical modifications in genes that don't directly affect a gene's DNA but result in changes in gene expression. Scientists think that chemical exposure, dietary habits and environmental factors may all have epigenetic affects. Most epigenetic changes are normal and may explain why pairs of twins l...Scientists find evidence of catastrophic sand avalanches, sea level changes in Gulf of Mexico
...fers to chemical modifications in genes that don't directly affect a gene's DNA but result in changes in gene expression. Scientists think that chemical exposure, dietary habits and environmental factors may all have epigenetic affects. Most epigenetic changes are normal and may explain why pairs of twins l...Long-sought flower-inducing molecule found
... also other data showing that these results can be directly applied to other species, such as poplar trees. Ove Nilsson says: "With the help of this knowledge plant breeders will get a new tool to control and adopt the flowering of plants, something that has been of great importance for agriculture but that c...Researchers develop gene therapy to reverse pulmonary arterial hypertension
...in, currently in trials in oncology, might also be directly applicable to PAH patients, Dr. Michelakis explains. The researchers are supported by the Canadian Institutes of Health Research and Canada Research Chair Program, the Alberta Heart and Stroke Foundation, the Alberta Heritage Foundation for Medical ...... step, according to Zhuo, is to determine how NR2B directly affects memory formation and storage in the brain. "While we know it exists in the hippocampus, amygdala and the pre-frontal cortex, we don't know exactly how it alters them," Zhuo says. "Once we understand the implications for each part, we will be ...Molecular mechanism of feather formation found
...riations in the initial number of barb ridges will directly affect the shape, and consequent function, of the feather." To test the activator-inhibitor model, Harris injected retroviruses to force the expression of either Shh or Bmp2 into the skin of six-day-old chick embryos. The virus infected only small p...Cells direct membrane traffic by channel width
... So his team now is looking beyond the amino acids directly lining the channel to find what it is that forces changes in size. The same principles, he added, likely apply to all selective protein channels. Understanding the principles could provide new, effective pharmaceutical targets to control the channel...Vaccine targets tumors where they live
...ng. The data represent the first clinical trial to directly inject a vaccinia virus expressing the B7.1 costimulatory molecule into humans with melanoma. The researchers show that this vaccine is safe and feasible to use for local delivery into established melanoma lesions. 2 of the injected lesions showed a...Scavenger cells could be key to treating HIV-related dementia
... of the study. "In a way, it's not the virus that directly causes the dementia," Salemi said. "It's the fact that there is this continuous migration of infected macrophages to the temporal lobe. The virus mutates much faster there, the macrophages keep accumulating and keep creating this inflammation that le...New partnership to clear landmines for African Elephants
...U.N. Development Program-Angola. RoP will contract directly with demining organizations and work with Angola-based staff funded by the U.S. Department of State. CI will then take part in ecotourism development based on wildlife conservation within the Luiana reserve, thereby contributing toward social and env...New discovery blurs distinction between human cells and those of bacteria
...," Yeates said. While microcompartments have been directly observed in only a few organisms, "surely there will be many more," Yeates said. "The capacity to create subcellular compartments is very widespread across diverse microbes. We believe that many prokaryotes have the capacity to create subcellular com......," Yeates said. While microcompartments have been directly observed in only a few organisms, "surely there will be many more," Yeates said. "The capacity to create subcellular compartments is very widespread across diverse microbes. We believe that many prokaryotes have the capacity to create subcellular com...