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Tag: "directly" at biology news

Human Eggs Can Develop From Ovarian Surface Cells In Vitro

...own for the first time that human eggs may develop directly from cultured ovarian surface epithelium (OSE) cells derived from adult human ovaries. Oocytes derived from the culture of OSE cells developed in vitro into mature eggs suitable for fertilization and development into an embryo. These findings, publis...

Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips

...pairs causing the mutation could be found and then directly introduced into a new strain. Drug companies use chemicals and radiation to damage DNA and induce mutations. But it's not easy to detect these single base-pair mutations in the so-called industrial mutant strains. Kao's group, for example, detected ...

While on trail of dioxin, scientists pinpoint cancer target of green tea

...n the same way as other AH antagonists, by binding directly to it. We were completely surprised that this isn't the case," says Gasiewicz, whose work was funded by the National Institute of Environmental Health Sciences and the American Institute for Cancer Research. Instead, the team found that EGCG binds t...

Ebola virus: from wildlife to dogs

.... Research now indicates that humans do not become directly contaminated from the animal reservoir, which is an any case still unknown, but from infected carcasses of chimpanzees, gorillas and certain forest antelopes. Results have come from work conducted over the past several years by IRD scientists and the...

Researchers test new therapy for advanced melanoma

... encodes a gene that stimulates the immune system, directly into the tumor site in mice. Then, they applied electroporation to the site to help the plasmid move into the tumor cells. The tumor cells used the plasmid's genetic instructions to make proteins. These proteins signaled the immune system to recogniz...

Experiment station researchers to explore genome of disease-fighting fungus

...roducers. "By placing the disease-fighting fungus directly onto the seed, it would continue to protect the plant throughout the growing season and spread throughout the root system." Finding unique genes involved in inducing plant resistance could also aid the greenhouse industry that encounters problems wi...

Research may provide new link between soft drinks and weight gain

...mine if high-fructose corn syrup in soft drinks is directly responsible for the current increase in human obesity. ...

Gene silencing technique offers new strategy for treating, curing disease

A new technique aimed at directly controlling the expression of genes by turning the...h cause disease. The information in a gene is not directly converted into proteins, but first is copied by special enzymes into many copies of messenger RNA, w...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

...dictive drugs, including cocaine and amphetamines, directly or indirectly raise dopamine levels. The neurotransmitter therefore plays a major role in drug-induced highs and in addiction, he explained. Neurotransmitters such as dopamine are chemical messengers that one neuron launches at receptors on another ...

Natural tumor suppressor in body discovered by UCSD medical researchers

...y. "Currently there are no compounds identified to directly stop Akt from causing cancer growth, once Akt sign...ation of Akt, no one to date had determined how to directly turn off Akt once it has been activated. Since the Akt molecule is locked in the "on" position when...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

...driven clinical trials planned at Moffitt can move directly into a PhaseI/II trial. With the step-up of functional-genomics research at Moffitt and around the country, the advent of "customized medicine" has been heralded in headlines and at medical conferences. The clinical trial of this Akt-inhibitor is a ...

The making and breaking of microtubules

...capturing transitional states of GTP-bound tubulin directly was impractical. Instead the researchers worked with a similar molecule, GMPCPP, an analogue of GTP that binds to the same site but is not vulnerable to hydrolysis. Using cryo-EM they were able to capture GMPCPP-bound tubulin during the initial step...

Fat's fate depends on its source

...in the May issue of Cell Metabolism. Fats taken in directly from the diet or generated from sugars spark a cascade of gene activity in the liver necessary for healthy blood levels of sugar, cholesterol, and other fats, according to the researchers. Old fat stores alone failed to set those critical metabolic ...

Study: Well-known protein helps stem cells become secretory cells

...ings suggest that this single transcription factor directly determines the amount of secretory activity in a given cell type," said Andrew. ...

Specialized immune-system B cells play double-barreled role

...ngs about the role of these B-1 cell subtypes will directly impact on vaccine development," said Tedder. "However, understanding such key characteristics of the immune regulatory process will be critical to learning to successfully manipulate it with vaccines." ...

It's electric: Cows show promise as powerplants

...elated experiment, the researchers used cow manure directly to create energy for a fuel cell. Using cow dung ... a cannula, a surgically implanted tube that leads directly from the cow's hide into its rumen. The cow used in the study ate a normal diet. The researchers fi...

Molecular steps involved in the creation of gene-silencing microRNAs identified

...udy, we were able to link processing of the miRNAs directly through to the molecules responsible for silencing genes," says Ramin Shiekhattar, Ph.D., an associate professor at Wistar and senior author on both Nature studies. "The miRNAs provide specificity for those molecules, which do the actual work of gene...

Scripps research scientists identify infertility molecule

...es, and finally having the early embryos implanted directly into their wombs (the technique of in vitro fertil...uences fertility, at least in mice -- and one that directly affects the ability of mouse embryos to implant in their mother's womb. LPA Receptors and Implantat...

International Team Determines Geographic Origin of Leprosy

...monly held view that leprosy spread to West Africa directly from East Africa, say the researchers. The international team of investigators, who identified rare genetic variations among strains of the bacterium that causes leprosy, included Patrick J. Brennan, Ph.D., of Colorado State University in Fort Colli...

New tool reveals secrets of migrating cells

...niversity of California, Berkeley. "The ability to directly visualize cells in living tissues has changed the ...al invaders. "We were surprised by how rapidly and directly the cells move to their final destination." The technique could allow researchers in many fields of...

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