A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...reast cancer, eventhough the tumors were implanted directly into mice. “This is an exciting strategy that seems to elicit a completeimmunologic response against HER2/neu,?says the study’s lead author,Lawrence Lachman, Ph.D., a professor in the Department of ExperimentalTherapeutics. “Now that we have gone as...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
...in its trachea, the series of tubes that carry air directly to cells for gas exchange. Using a respirometer (an instrument for measuring respiration that consists of a chamber with a flow-through air system), they monitored the moth's breathing pattern. The chamber, which housed the moth being studied, was fi...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...is important because itaddresses a problem arising directly from the biology."Dr. Daniel Gillespie, a pioneer in stochastic methods for modelingchemical kinetics stated, "Dr. Lok has succeeded in adapting andcreatively extending earlier developed techniques for stochasticallysimulating chemical reactions so t...Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
...till ahead is viewing cancer cells in fluids taken directly from the body, rather than isolated by type in a flask. This problem will be solved by winnowing out unlikely particles through size and frequency. ...UCSD discovery may help extend life of natural pesticide
...iversity, Griffitts and Aroian found that Bt toxin directly binds glycolipids. However, in each of the four Bt resistant mutants tested--bre-2, bre-3, bre-4 and bre-5--the researchers found that there was either zero or dramatically reduced binding of glycolipids to Bt toxin. They concluded that the defective...Study of genomic DNA leads to new advances in cancer diagnostics
...to the chromatin. Such changes can now be measured directly at the chromatin level. These findings may provide the basis for the design of a new generation of cancer therapeutic agents. Research was funded by the National Institute of Health and the Department of Energy. This work involved collaborators at ...New RNA polymerase discovered in plants
...to make RNAs that encode proteins or that function directly in the cell. Biologists have studied three kinds of RNA polymerase for decades in organisms ranging from brewer's yeast to humans. In all eukaryotes, the RNA polymerases Pol I, II, and III perform the same distinct , though separate, functions in di...The Bacteria's guide to survival
..., or programmed cell death. For bacteria that pass directly from host to host, this can pose a problem. If the...r pili. For bacteria like N. gonorrhoeae that pass directly from host to host, the researchers argue, it would be in a bacterium's interest to help keep its hos...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
...e in the development of B lymphoma. "TEL2 doesn't directly cause cancer," Grosveld said. "Instead, this gene promotes the development of lymphoma by enlarging the B lymphocyte population. This increases the likelihood that at least a few of the cells acquire a mutation eliminating p53 function just by chance...Key Trigger Of Opioid Withdrawal Symptoms Found
...ering extracellular GABA concentrations as well as directly altering the excitability of GABAergic neurons." ### Elena E. Bagley, Michelle B. Gerke, Christopher W. Vaughan, Stephen P. Hack, and MacDonald J. Christie: "GABA Transporter Currents Activated by Protein Kinase A Excite Midbrain Neurons during Opi...Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
...sive polymersome vesicle to transport therapeutics directly to a tumor, enabling us to actually see if chemotherapy is really going to its intended target." This work takes advantage of years of effort in the Therien laboratory focused on the design of highly fluorescent compounds. Polymersomes, which were d...Sexual cooperation: Mating increases longevity in ant queens
...ale re-mating probability or boost their fecundity directly after mating, but they can be very harmful to females, whose lifespan and future reproductive output can be drastically reduced. New findings suggest that in some social insects--in which both sexes ultimately benefit from long, successful reproducti...Drug-resistant bacteria on poultry products differ by brand
...hool of Public Health. Their study is the first to directly compare bacterial contamination of poultry products sold in U.S. supermarkets from food producers who use antibiotics and from those who claim they do not. The study focused on antibiotic resistance, specifically fluoroquinolone-resistance in Campylo...Epstein-Barr virus protein crucial to its role in blood cancers
...esearch into how EBV drives the cancer process has directly identified a critical component of the cell cycle for control. Now we can develop targeted therapeutics to disrupt the function of this viral protein." The researchers surmise that the first use of future therapies from these studies will be in lymph...Defensins neutralize anthrax toxin
...esearch into how EBV drives the cancer process has directly identified a critical component of the cell cycle for control. Now we can develop targeted therapeutics to disrupt the function of this viral protein." The researchers surmise that the first use of future therapies from these studies will be in lymph...Alzheimer's cognitive decline slowed
...patients with genetically modified tissue inserted directly into their brains show a reduction in the rate of cognitive decline and increased metabolic activity in the brain, according to a study published in the April 24, 2005 online issue of the journal Nature Medicine by researchers at the University of Ca...Microbial fuel cell: High yield hydrogen source and wastewater cleaner
...ables bacteria to coax four times as much hydrogen directly out of biomass than can be generated typically by fermentation alone. Dr. Bruce Logan, the Kappe professor of environmental engineering and an inventor of the MFC, says, "This MFC process is not limited to using only carbohydrate-based biomass for h...Anti cancer virotherapy well tolerated in first human administration, research finds
...ected a single dose of Coxsackie A21 (CVA21) virus directly into the advanced melanoma tumours of these patien...sted that administration of a single dose of CVA21 directly into a cancerous tumour was well tolerated. "Administration of CVA21 may be of potential therapeuti...Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes
...rosclerosis ("hardening of the arteries"), and not directly life-threatening. However, there is recent evidence that people with dolichoectasia are more likely to have aortic aneurysms, a potentially fatal weakening of the main artery that carries blood out from the heart. In an article published online Febr......ead the idea that the plagues of Europe were not a directly infectious disease but were outbreaks of bubonic plague, overturning an accepted belief that had stood for 550 years. Professor Duncan and Dr Scott illustrated in their book, Return of the Black Death (2004, Wiley), that this idea was incorrect and t...