Elusive HIV shape change revealed; Key clue to how virus infects cells
... whether there are any immunologic properties that differ and that might provide a route to new vaccine or drug strategies," Harrison says. ...Gene variations explain drug dose required to control seizures
...g recognized that patients with the same condition differ in their responses to the same drugs," said neurologist and epilepsy specialist Sanjay Sisodiya, M.D., leader of the University College London effort and co-author of the study. "This study establishes the principle that genetic differences between p...Scientists decipher genome of fungus that can cause life-threatening infections
... "Although the two Cryptococcusstrains we examined differ significantly in virulence, we foundsurprisingly l...h includes three related yet diverged specieswhich differ in virulence attributes, environmental distribution andwhich have been diverging over millions of ye...Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance
...d uncertainties that could cause actual results to differ materially for Affymetrix from those projected, including, but not limited to risks of the Company's ability to achieve and sustain higher levels of revenue, higher gross margins, reduced operating expenses, uncertainties relating to technological ap...VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
... strains known as B6 and D2. The two mouse strains differ in a number of behavioral responses to acute alcohol and in their predisposition to drink alcohol. Researchers isolated tissue from three different regions of the brain that are all known to play a role in responses to alcohol and other drugs of abu...Cricket's finicky mating behavior boosts biodiversity
... in the pulse rates of male courtship songs, which differ from one Laupala species to the next. They refuse to mate with males of other species, thus promoting the formation of new species. The scientists say their findings shed light on the role of individual choices in the evolution of species and the gr...Variation in women's X chromosomes may explain differences among individuals, between sexes
...nown to consist of a mosaic of two cell types that differ in which X chromosome is inactivated. The Y chromosome also endows males with at least several dozen expressed genes that females lack. The incomplete nature of X inactivation, demonstrated in the new study, means that at least 15 percent of the X-l...Increased risk of osteoporosis associated with gene that one in five people have
...iations of the CYP1A1 gene exist, and the variants differ from one another by one or more DNA base pairs. "Previous studies showed that some CYP1A1 variants are linked to estrogen-related cancers, such as breast, ovarian or endometrial cancers," says Reina Armamento-Villareal, M.D., assistant professor of ...New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal
...est the method in people. These concentrations can differ widely from those found in the bloodstream, said Derendorf, who has published results from studies that evaluated the technique in people and animals with various infections. In the past, microbiologists would expose bacteria to certain concentration...Stanford gut check shows diversity of intestinal ecosystem
...d the samples to examine how microbial communities differ among locations within the intestine as well as among different people. "We were surprised at the degree to which an individual determines the particular picture of microbial diversity that we see," said Relman. "Variation between individuals had be...Research shows smoking adds a decade to reproductive age of IVF patients
...nt out that the success rates from this data might differ from success rates today, as success rates have increased since 1995 when the OMEGA study began. ...An (ecological) origin of species for tropical reef fish
...port coral reef fish from neighboring habitats may differ more from one another than from fish thousands of miles away. An ecological speciation model for coral reef organisms may spur the development of a more synthetic treatment of speciation on land and sea. Coral reefs, like tropical forests, express a......ritic versus normal joints. While OA cells did not differ from controls, primary RA cells produced TNF-a, IL-1ß and IL-6 at levels 2- to 4-fold above controls. Importantly, this effect could be replicated in normal cells when they were engineered to express Wnt-7b, demonstrating the importance of Wnt-7b in ...Can our genes tell the story of our divergence?
...t tree-bound nests high above the forest floor. We differ by just a tad over 1% at the DNA sequence level, yet scientists predict that both species should harbor genetic footprints of our divergence ?the subject of a recent study in the premier open-access journal PLoS Biology. One way to find such genetic...Divergent life history shapes gene expression in brains of salmon
...n have found that gene expression in the brain can differ significantly among members of a species with different life histories. Their study indicates that roughly 15 percent of Atlantic salmon genes show differential expression in males who migrate from their freshwater birthplaces to mature in oceans ver...Looks matter to female barn swallows
...female barn swallows use to assess potential mates differ according to regional tastes. For example, classic studies have shown that in the very closely related European barn swallow ( H. rustica rustica) , males with long tail feathers attract more mates. Although many previous studies have investigated m...A slight difference and significant similarities
...d that of conventionally bred varieties. They only differ in the new substances intentionally incorporated with gene technology. This conclusion has been reached by scientists at the Max Planck Institute of Molecular Plant Physiology and their colleagues from the University of Wales in a study published in ...AIDS expert says global strategy needed to combat feminization of HIV/AIDS
...America. The reasons for the rise in female cases differ among countries, with 97 percent of female HIV infections in the United States due to heterosexual transmission (81 percent) and intravenous drug use (16 percent). In the developing world, heterosexual transmission is responsible for nearly all of th...From a Few Wild Ancestors, a Citrus Cornucopia
...r mutations from a parent tree -- so they wouldn’t differ enough from other accessions to be surveyed. “About 50 of the 400 accessions represent more than 90 percent of the collection’s true diversity,?says Krueger. “That’s just 13 percent of the collection.?/p> That may sound surprising, but it reinfo...Virtual animal shelters ?How the Internet is transforming the experience of pet adoptions
... cats. She says the informative, personal messages differ from the brief descriptions on cages in traditional animal shelters, but adds that independent rescuers may be taking care of one or two pets at a time while a shelter may be struggling to adopt out hundreds of animals each week. Additional benefits...