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Tag: "die" at biology news

Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds

...e disease are confined to a wheelchair and usually die in their 20s. There is currently no effective treatment for the disease, which explains why gene therapy remains a hope despite the significant hurdles. Rando said the PNAS paper highlights an additional requirement for any gene therapy to be succes...

Pulp mill devastates swans' sanctuary in Chile

...ntaminants from the plant contributed to a massive die off of luchecillo, the aquatic vegetation that was the swans' main food source. "It was heart-rending. We talked to people in Valdivia who said they saw emaciated swans fall from the sky, landing on rooftops and cars," Curtis said. "They were so we...

New neurons take baby steps in the adult brain

...nt efforts are the dopamine-producing neurons that die in Parkinson's disease, muscle-controlling nerves that succumb in diseases like muscular dystrophy and amyotrophic lateral sclerosis, or nerves that are damaged by trauma or injury. In none of these systems are new neurons formed or integrated to any...

Dangerous tricksters: Some bacterie use immune cells to reproduce

... after the onset of the infection, the macrophages die of the infection, they disintegrate and release the multiplied pathogens. The Bonn cell biologists have demonstrated in the past that this cell death is 'necrotic'. This means that cell components escape, attract other immune cells and activating th...

Scientists map one of biology's critical light-sensing structures

...t tells them when to flower. It tells them when to die at the end of the growing season." The accomplishment of the Wisconsin researchers, including first author graduate student Jeremiah Wagner, caps a 30-year quest by biologists to drill down to the inner workings of how plants, fungi and bacteria use...

Shorter colds, milder flu may follow from newly revealed immune mechanism

... signaling proteins that allow the cell to live or die in the face of infection. Identifying these signals may allow us to regulate these signals during an infection, and so make epithelial cells and macrophages more effective to shorten recovery time or lessen symptoms." The ability to decrease the sev...

Clinical trial to test stem cell approach for children with brain injury

...ility among children, and the main reason children die from trauma is brain injury, Cox said. The proposal was under review for a year. The U.S. Food and Drug Administration approved Cox's Investigational New Drug (IND) application in September. The UT-Houston CPHS, the university's institutional revie...

Compound from marine bacteria shows potential as multiple myeloma therapy

...nted proteins. With their proteasome jammed, cells die from the backup of damaged proteins. "Proteasome inhibition is a key therapeutic target and bortezomib (Velcade tm) was the first in a new class of compounds in multiple myeloma. NPI-0052 is a novel proteasome inhibitor with a chemical structure an...

Is it Possible to Change Prescribing Habits?

In the US more than 770,000 people are injured or die each year in hospitals from adverse drug events (ADEs), which can cost a hospital, depending on its size, about US$5.6 million every year, excluding ADE-associated costs for malpractice and litigation and the personal costs of injuries to patients. ...

Health of coral reefs detected from orbit

...ive colours) are expelled. The whitening coral may die with subsequent impacts on the reef ecosystem, and thus fisheries, regional tourism and coastal protection. Coral bleaching is linked to sea temperatures above normal summer maxima and to solar radiation. Bleaching may take place on localised and mas...

Limiting the damage in stroke

...hin brain cells may determine whether they live or die after a stroke. Their study, published online (November 13) by Nature Medicine, strongly suggests that new therapies for victims of strokes could be developed by controlling a molecule involved in passing the signal. Strokes lead to death or permane...

Cord blood cells may widen treatment window for stroke

... challenges the notion that nerve cells inevitably die quickly in the core region of the brain most severely deprived of oxygen and nutrients when a stroke hits. Instead, the researchers suggest, many nerve cells within ground zero of the attack, like those in mild to moderately damaged outlying areas, m...

Worms know bad food when they smell it

...e worm has ingested enough of the bacteria, it can die quickly, but milder cases allow the worm to live for several days ?and head off in search of better food. So, the researchers surmised, knowing whether or not certain bacteria are toxic is something "worth learning" for the worm. To find out wheth...

Johns Hopkins flu expert calls for mandatory vaccination of health care workers

...he job and that each year, nearly 40,000 Americans die from influenza, many of them elderly or ill, with weakened immune systems that cannot readily fend off the disease. In an editorial to be published in the journal Infection Control and Hospital Epidemiology online Nov. 9, Trish Perl, M.D., M.Sc., co...

Common viruses may cause cancer

...be harmless because they are generally believed to die without consequences for the host. According to a recent study, however, cell fusion triggered by viruses is a possible contributing factor in the development of human cancer. The study also raises concerns about the use fusogenic viruses as vectors ...

Research: Snails were overlooked contributors to marsh destruction

... off the flats and concentrated on the edge of the die off, where healthy grass remained. This migration ...rass. They put enclosures in the path of expanding die offs, as well as in remnants of healthy marsh. After 14 months, the patches were "robust and green" ...

GROWing the next generation of water recycling plants

...cular species' tolerance level. Should one species die off, there will still be others there to continue the job until the dead plants can be replaced. The beauty of the system is that it is not 'high-tech' in the traditional sense. "It does not require sophisticated maintenance, just tending, like any...

Sensors, a smart dose of medicine for cancer treatment

...packaged diodes out there we needed diodes in bare die form with some novel properties so we developed the diodes ourselves, here at the Tyndall Institute," says Jaksic. The arrays are extremely accurate and can track radiation at micro-Gray resolution over millimetres of spatial resolution. These are...

Preclinical study of a new brain tumor therapy

...malian cells from viruses, cells are programmed to die once they take up this particular nucleic acid. The treatment therefore eliminates the tumor cells but avoids damage to the normal brain tissue. The researchers found that the treatment was effective in mice implanted with human brain tumor cells t...

Antibacterial coatings cut infection rates

...y don't start producing the biofilm and eventually die on the surface. "We attach the furanones by covalent bonding to our biomedical devices. We stress covalent bonding because it is important that we anchor them very firmly to the surface, making it impossible for them to break away and travel into re...

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