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Tag: "diagnostic" at biology news

Large-scale genomics project will hunt genes behind common childhood diseases

...nt. "Our goals for the Center are to generate new diagnostic tests for childhood diseases, to use this diagnostic knowledge to guide physicians to the most appropriate therapies. In addition, we plan to form strate...

Patients to benefit from novel technology revolutionizing high-speed molecular imaging

...des better image quality and opens the door to new diagnostic procedures using simultaneous multi-isotope imagin...n dose that can be administered for the purpose of diagnostic imaging," said Patton. "In addition to this limitation, the low efficiency of existing SPECT imaging...

Analysis of breast-cancer gene role offers promising target

...the gene, which is a very reliable and easy-to-use diagnostic test called FISH," said Dr. Tripathy. "The other important finding is that HER-2 and uPAR gene amplification tend to co-exist, and this has implications in new strategies to address HER-2-positive breast cancer with drugs that block both HER-2 and ur...

Tests for 'face-blindness' reveal disorder may not be so rare

...rsity and University College London have developed diagnostic tests for prosopagnosia, a socially disabling inability to recognize or distinguish faces. They've already used the new test and a related web site ( www.faceblind.org ) to identify hundreds of "face-blind" individuals, far more than scientists had i...

High dopamine transporter levels not correlated with ADHD

...icate that levels of a brain protein proposed as a diagnostic marker for attention-deficit hyperactivity disorder (ADHD) are not positively correlated with the disease. In fact, the study found lower levels of these "dopamine transporter" proteins in certain brain regions of ADHD patients compared with controls...

Pure carbon nanotubes pass first in vivo test

...bes end up, and it opens the door to some exciting diagnostic and therapeutic applications." In a ground-breaking 2002 study, Weisman and colleagues at Rice, including the late Professor Richard Smalley, discovered that nanotubes fluoresce, or emit near infrared light. Because near-infrared light passes harm...

Study offers innovative profile of enzyme that aids tumor growth

...ing KIAA1363 itself, might be considered potential diagnostic markers for ovarian cancer." This experimental method of integrated molecular profiling used in the study should also advance the functional study of metabolic enzymes in any biological system, according to Cravatt. To date, understanding the ro...

New technology used to construct the first map of structural variation in the human genome

...pment of the algorithm. "We'll be able to develop diagnostic tests with sub-microscopic resolution, and because the analysis detects SNPs--single-nucleotide polymorphisms--in addition to CNVs, it will find widespread use among researchers performing disease-association studies." ...

Three-dimensional, miniature endoscope opens new diagnostic possibilities

...eatly expand the application of minimally invasive diagnostic and therapeutic procedures. In the October 19 issue of Nature, the team from the Wellman Center for Photomedicine at MGH describes their prototype device and a demonstration of its use in a mouse model. "This new ultraminiature endoscope is the f...

Mars mission Risk 29: Scientists research ways to reduce radiation-induced brain damage

...nduced cognitive impairment and the development of diagnostic biomarkers David Chen, University of Texas Southwestern Medical Center, Dallas, mechanisms of the repair of HZE-induced DNA double-strand breaks in human cells Albert Fornace, Harvard School of Public Health, Boston, mouse models approach for i...

Cardiologist's 'living chip' changes science of disease monitoring

...ilure and other health conditions, blood draws and diagnostic tests are commonplace in order to evaluate their c...es that individual patients respond differently to diagnostic and therapeutic interventions," Rosero said. "The key to personalizing an individual's care is to im...

Brains can recover from alcoholic damage but patients should stop drinking as soon as possible

...nd brain volume," wrote the associate professor of diagnostic radiology and psychiatry at Yale University. Prof Mason believed this was a particularly valuable contribution of the study because "patients often become discouraged from the physical and cognitive difficulties of achieving and maintaining sobriety...

Common cold virus leads to death in lung transplant patients

...nt might have substantial implications in terms of diagnostic procedures, clinical management, and anti-viral use, if available." In an editorial on the research in the same issue of the journal, Marc B. Hershenson, M.D., of the University of Michigan, Ann Arbor, and Sebastian L. Johnston, M.D., Ph.D., of th...

MIT designs portable 'lab on a chip'

... MIT researchers who are helping to develop a tiny diagnostic device that could be carried into battle. By tweaking the design of a tiny pump, researchers affiliated with MIT's Institute for Soldier Nanotechnologies have taken a major step towards making an existing miniature "lab on a chip" fully portable, so...

World-wide warning of highly drug-resistant tuberculosis

...ed to be improved, highlighting the need for a new diagnostic test," he writes. "Technologies that can determine the presence of drug-resistance at the point of care are needed as are new drug treatments."...

Silver bullet: UGA researchers use laser, nanotechnology to rapidly detect viruses

... University of Georgia researchers has developed a diagnostic test that can detect viruses as diverse as influen...deletions. This specificity makes it valuable as a diagnostic tool, but also as a means for epidemiologists to track where viruses originate from and how they cha...

Novel regulatory mechanism identified for key tumor suppressor p53

... newly identified enzyme might also be useful as a diagnostic marker for cancer." Responsible for tumor suppression throughout the body, the p53 protein has been found to be mutated and dysfunctional in more than half of human cancers. When working properly, p53 acts by binding to DNA to activate genes that d...

Faster, more accurate tuberculosis test developed

...ine. "In the fight to stop the spread of TB, new diagnostic tools are urgently needed to detect TB and multidrug-resistant TB. MODS is just such a tool. It will change the practice of TB testing in developing countries," said Robert H. Gilman, MD, senior author of the study and a professor in the Bloomberg Sc...

First biomarker for human sleepiness identified in fruit flies

...e levels correlate with sleep debt, but for a good diagnostic test we're likely going to need more than one biomarker," Shaw says. "So we're going to continue to use the processes that we've developed to look for other substances that change in connection with the level of sleep debt." Stephen L. Duntley, M....

HIV/AIDS linked to extensively drug resistant TB

... Friedland said there is a desperate need for new diagnostic tests and treatment for TB. "It is still being diagnosed the same way it was in 1882," he said. "Modern technology for diagnosis and new treatment needs to be developed urgently. The last approved TB drug was 40 years ago." ...

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