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Tag: "diagnostic" at biology news

Toxic molecule may cause most common type of muscular dystrophy

... on chromosome 19, which is now part of a genetic, diagnostic test for myotonic dystrophy. In their latest research, Mahadevan and colleagues created a new type of mouse model with many extra copies of the CTG repeats, each attached to DNA for a protein that glows green under a microscope. They also integrat...

Matrilin-3 gene discovered to prevent onset of osteoarthritis

... osteoarthritis. Potentially, we could use it as a diagnostic tool or to predict whether someone is likely to develop osteoarthritis," says senior author Qian Chen, PhD, director of cell and molecular biology, and head of orthopaedic biology research at Rhode Island Hospital. Chen is also a professor of medi...

New genetic test for breast cancer

...early-stage breast cancer. "By using a molecular diagnostic test to assess whether a breast tumor will respond... The researchers will use OncotypeDXTM, a modern diagnostic test developed by Genomic Health, Inc., in Redwood, Calif., in collaboration with the National Surgi...

MIT 'seeing machine' offers hope to blind

...ard, where technicians peered into her eyes with a diagnostic device known as a scanning laser opthalmoscope, or... But although the SLO held promise as more than a diagnostic device, it had serious drawbacks. In addition to the prohibitive cost, the SLO is large and bulky. G...

'Signature' of chromosome instability predicts cancer outcomes

...nt, the team's work could also form the basis of a diagnostic tool that could be used in the clinic. The human genome is at constant risk for mutations due to environmental insults, errors in gene replication, and other factors that can cause chromosomes to break and bits of DNA to be lost, duplicated or resh...

Fish virus in Northeast spreading to other fish species

...ture technique to perform the initial stage of the diagnostic testing. This technique can take two to four weeks to yield results. Cornell researchers are developing a molecular-based test for VHSV based on a specific gene sequence in the virus. Once available, the new technique will cut the turnaround for con...

How HIV 'exhausts' killer T cells

...searchers are also exploring PD-1 measurement as a diagnostic tool, said Walker. "Currently, we just count the number of helper T cells to decide when to treat someone, but we are excited about the possibility that adding PD-1 measurement might tell us more about the likelihood of progression of the disease and...

A new tool against brain disease

...searchers are also exploring PD-1 measurement as a diagnostic tool, said Walker. "Currently, we just count the number of helper T cells to decide when to treat someone, but we are excited about the possibility that adding PD-1 measurement might tell us more about the likelihood of progression of the disease and...

Researchers uncover new mechanism of tumor suppressor

...se cancer. Their findings, which could lead to new diagnostic markers and cancer treatments with fewer side effects, will appear in two reports in the May 21 advanced online version of the journal Nature. The studies, led by Tatiana Kutateladze, PhD, an assistant professor in the UCDHSC Department of Pharmacol...

Connect the Quantum Dots

... "Our method has a long-term impact on biomedical diagnostic applications which currently rely on the fluorescence of organic dyes," says Francisco Raymo, Ph.D., associate professor of chemistry in the University of Miami's College of Arts and Sciences. "For example, our strategy can be designed to signal spec...

Smooth sailing: 'cruise ship virus' tackled by UH, Baylor College of Medicine

... a long time," Ruchhoeft said. "If we can build a diagnostic tool that mimics something like the pregnancy test...center is certainly interested in a more effective diagnostic tool for Norwalk, it foresees using this approach for other diseases, as well. "If someone else ...

Cornell researchers find serious fish virus in Northeast for first time

...owser and colleagues are trying to develop a rapid diagnostic test, called a PCR (polymerase chain reaction), which would amplify and detect small amounts of viral DNA or RNA in a blood or tissue sample. Although no management decisions have yet been made, the DEC could recommend that boaters clean their boa...

Even when faint, ovary scent draws sperm cells

...y, sperm chemotaxis could potentially be used as a diagnostic tool to determine sperm quality or as a therapeutic procedure in male infertility," Jacobson said. The project is a collaboration between research groups led by Jacobson and IUB Distinguished Professor of Chemistry Milos V. Novotny. Their work led ...

Researchers find cause of frontotemporal dementia

... that too little progranulin underlies FTD. New diagnostic and therapeutic possibilities This discovery does not directly result in a new remedy for FTD patients ?a lot more research is needed for that. But this finding does offer the prospect of a new treatment for FTD and possibly also for other diseases ...

Combined treatment extends life expectancy for lung cancer patients

...trasound at Rhode Island Hospital and professor of diagnostic imaging at Brown Medical School, both in Providenc...directly to cancerous cells with the guidance of a diagnostic image showing the tumor's location. However, if some cancerous cells have spread into small channels...

Coming soon: 3-D imaging that flies 'through' and 'around' cancer

...oscopy." This imaging technique "may add important diagnostic information that may herald new applications for the use of PET/CT," he noted. In addition, its diagnostic value was demonstrated in one case in which it revealed a cancer lesion that had not been detected b...

Smell of success for nanobiosensors

...t on other sectors. A major challenge of these new diagnostic tools lies in the establishment of a precise odorant disease signature, understood as the mix of volatile compounds whose concentration in a body fluid (i.e. urine, blood, pus, etc) or in the breath varies in patients with the malignancy with respect...

Speeding the search for elusive chromosomal errors

...t the end of each chromosome. Recent advances in diagnostic gene chips, used by Dr. Shaikh's team, allow more precise analysis of very small DNA alterations throughout all of a patient's chromosomes. Gene Chips Detect Tiny Structural Defects in Genomic Diseases Conditions that originate in alterations of ...

Mice learn tasks that may help treat human psychiatric disorders

...ant to such disorders in humans, research into new diagnostic methods, treatments and cures is severely hindered," said Joseph Garner, a Purdue assistant professor of animal sciences and the study's lead author. "The level of complexity at which we assess mouse behavior is often very rudimentary, and it just do...

Scientists describe new African monkey genus ?first in 83 years

...ternal features of the specimen do not exhibit the diagnostic morphological features of baboons: namely, a long rostrum or deep depressions on the outside of the lower jaw. Also, depressions under the orbits of the Kipunji skull are much different than those of baboons, mandrills, and geladas. Given the resul...

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