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Tag: "diabetes" at biology news

Free-energy theory borne out in large-scale protein folding

...y but mysterious role in Alzheimer's, Parkinson's, diabetes and a host of other diseases, so mapping the normal route a protein takes - and finding the off-ramps that might lead to misfolding ?are vitally important," Wittung-Stafshede said. Rice's studies were carried out on monomeric lactose repressor prote...

Effective, safe anthrax vaccine can be grown in tobacco plants

...lds promise for treating other diseases, including diabetes and hepatitis, and improving vaccines for plague, cholera and other bioterrorism agents. Daniell is developing a new technology that would enable vaccines to be administered orally and allow effective and less expensive treatments to be more accessi...

New methods offer insight into regulatory DNA

...on base-pairs ?that is known to be associated with diabetes and obesity. In comparison with gene sequences that contain the instructions to make proteins, regulatory regions that control genes are relatively poorly understood. Their structure is variable and their distance from the genes they control also va...

Scientists directly view immune cells interacting to avert autoimmunity

... prevent and even reverse the course of autoimmune diabetes in mouse models, and this study begins to analyze ...eproduce in vitro." The team of immunologists and diabetes researchers used the new microscope to show that when Treg cells are absent, the potentially destruc...

Diabetes researchers pioneer islet cell xenotransplantation in primate studies

...ard and proves neonatal porcine islets can correct diabetes long-term in primates," said Drs. Korbutt and Rajotte. "To meet the needs of the millions suffering from type 1 diabetes, we must find new donor sources to allow large-scale application of islet cell transplantation in humans," said Dr. Larsen. "Whi...

Researchers map of genetic variations implicated in disease

... own systems. The MHC has the major role in type 1 diabetes and rheumatoid arthritis. The MHC is also pivotal ...at least 30% of the familial aggregation in type 1 diabetes and rheumatoid arthritis. "Data generated by projects such as the MHC Haplotype Project will feed i...

Learning to love bacteria: Stanford scientist highlights bugs' benefits

...es such as ulcerative colitis, Crohn's disease and diabetes have increased. "All these observations have been made without necessarily trying to pull it all together," said Falkow. "So what I tried to do in this article is to point out that the continued presence of these organisms in human society may actua...

Scientists look to the Bahamas as a model for coral reef conservation

...es such as ulcerative colitis, Crohn's disease and diabetes have increased. "All these observations have been made without necessarily trying to pull it all together," said Falkow. "So what I tried to do in this article is to point out that the continued presence of these organisms in human society may actua...

Researchers reverse juvenile diabetes in animal model

...Giannoukakis, PhD, observed marked amelioration of diabetes in a mouse model by a novel treatment strategy inv...he animal's own dendritic cells, thereby reversing diabetes in animal studies. The U.S. Food and Drug Administration (FDA) approved the start of a clinical tri...

Darkness unveils vital metabolic fuel switch between sugar and fat

... also presents a new target for obesity and type 2 diabetes research. A series of experiments pinpointed 5-prime adenosine monophosphate (5'-AMP) as the key molecular mediator of the constant darkness effect, switching mice from a glucose-burning, fat-storing state to a fat-burning, glucose-conserving lethar...

Study by Einstein researchers could lead to a novel strategy for treating obesity

...pies not only to treat obesity but to help prevent diabetes and other consequences of being overweight." ...

Multi-million pound UK Biobank underway

... diagnosis and treatment of cancer, heart disease, diabetes and many other serious conditions is launched this week after several years of meticulous planning. Up to three thousand people living in the south Manchester area are being given the opportunity to trailblaze the project before it goes nationwide l...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...very of the genetic causes of common diseases like diabetes and hypertension. At the same time, it's critical that we also understand the environmental contributors to sickness, and the interplay among genes and environment. There is not a moment to be lost." GEI will have two main components: a laboratory ...

For the first time: Longevity modulated without disrupting life-sustaining function

... humans in order to prolong life, you would induce diabetes right away," cautioned graduate student and first author Suzanne Wolff. When this pathway had been clipped in worms, they lived longer than normal, but their larval development and reproduction were disrupted. "So, the central question became whethe...

Hap1 protein links circulating insulin to brain circuits that regulate feeding behavior in mice

...trolling eating behavior." "Scientists know that diabetes and obesity are related to abnormalities of hypothalamic function," Li said. "This is a complicated pathway, and Hap1 can help us explain it and hopefully manipulate it to treat disorders associated with abnormal energy balance in the brain." Stu...

Thinner and younger

...ng the risks of some age-related diseases, such as diabetes and atherosclerosis. But in animal studies not only did more of the animals live longer, the maximum length of a rat's or mouse's life also increased. The CALERIE study hopes to get some clues about whether calorie restriction might do the same thing...

Trial success for diabetic nerve therapy

...ound-breaking treatment for nerve damage caused by diabetes has shown promising results in preclinical and ear...utations carried out in UK hospitals are caused by diabetes and there are currently no treatments available to prevent or slow the progress of nerve disease in ...

Traditional Chinese medicine for diabetes has scientific backing

...r Jiming Ye says: "Our studies in animal models of diabetes show that berberine acts in part by activating an ...y weight". Current medicines for treating type 2 diabetes include metformin and the TZD group of drugs. However, alarge number of patients cannot tolerate met...

New pathways for autoimmune treatment identified

...ct that can trigger a host of diseases from type 1 diabetes to alopecia has helped explain the imbalance of im...d bad immune cells prevented development of type 1 diabetes in an animal model for the disease. But Drs. Mi and She say new i NKT boosters likely are needed ...

One-third of adults with diabetes still don't know they have it

The prevalence of diagnosed diabetes in U.S. adults age 20 and older has risen from abo...However, the percentage of adults with undiagnosed diabetes did not change significantly over the years studied. About 2.8 percent of U.S. adult--one-third of ...

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