Newly discovered genetic disease sheds light on body's water balance
...e kidneys to retain water. The opposite condition, diabetes insipidus, is caused when the arginine at R137 is changed to histidine, and the resulting V2 receptor signals the kidneys to excrete water excessively. To test the hypothesis that V2 receptors were active in their patients even though vasopressin wa...Researchers identify new genes that regulate aging
...nding human genes could potentially play a role in diabetes and cancer, according to senior author Cynthia Kenyon, of the University of California, San Francisco, and her coauthors. Citation: Hansen M, Hsu AL, Dillin A, Kenyon C (2005) New genes tied to endocrine, metabolic, and dietary regulation of lifespa...Exercise training in ordinary people affects the activity of 500 genes
...men. Some of these genes are most likely linked to diabetes and cardiovascular disease. These training study findings can therefore be important for the development of new treatment strategies for such diseases. Some people respond more easily to training than others. It is not known what explains this. The ...Insulin pulses keep the liver lean
...ilure to make or respond to insulin in people with diabetes causes blood sugar levels to rise. The current st...ulting hikes in blood sugar and fat can also spell diabetes and heart disease, Najjar added. "When we eat, the pancreas produces insulin, which stimulates the ...Fruit fly studies open new window on cancer research
...ing our understanding of processes associated with diabetes as well as cancer. We're fortunate that there are a number of groups with clinical interests in these areas in close proximity to us, which should help us assess the medical significance of our discovery." Fruit flies are used in research because a...Malfunctioning bone marrow cells sabotage nerve cells in diabetes
... ago, when we were developing gene therapy to cure diabetes in mice. By chance, we observed insulin-producing bone marrow cells outside the pancreas, and wondered why these cells were migrating to other organs and whether they were detrimental or beneficial," said Chan. In pursuit of this curious phenomenon,...Seaweed could make junk food healthier
...eapon in the international battle against obesity, diabetes and heart disease and diseases such as bowel cancer. The research paper examines the properties of a brown-coloured seaweed called Lessonia and Laminaria, found in the Far East, South America and parts of Norway and Scotland. The seaweed is processe...Energy management in cells may hold key to cancer defense
... combating cancerous tumor growth, but also type 2 diabetes and obesity. The study, published in the August ...tempting target for the treatment of some forms of diabetes and even obesity," said Witters. As Witters' laboratory continues to zero in on the central role of...New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
A key obstacle to early detection of type 1 diabetes - as well as to rapid assessment of the effectiven... of the Journal of Clinical Investigation. Type 1 diabetes is an autoimmune disease in which the body's immune system mistakenly attacks its own insulin-produc...UCSD study clarifies insulin's role in blocking release of energy in patients with type II diabetes
...physicians to bring down insulin levels in Type II diabetes using medicines called insulin sensitizers, so tha... time ?which happens in many patients with type II diabetes –the normal catecholamine signal that triggers fat breakdown and energy release can be drowned out. ...Life-extending protein keeps blood sugar in check
...ight improve insulin response in those with type 2 diabetes without causing other problems." Pancreatic b cel...ilure to make or respond to insulin in people with diabetes causes blood sugar levels to rise. The researchers found that Sirt1 is present in pancreas cells th...Sea Ice May Be on Increase in the Antarctic
...ight improve insulin response in those with type 2 diabetes without causing other problems." Pancreatic b cel...ilure to make or respond to insulin in people with diabetes causes blood sugar levels to rise. The researchers found that Sirt1 is present in pancreas cells th...Protein structure key for AIDS, cell function
...lved in certain diseases, ranging from leukemia to diabetes and HIV-AIDS. Levels of the protein climb, for reasons unknown, when people fall ill, making human CD38 a marker for these diseases. As one example, researchers have shown that CD38 interrupts an interaction between the AIDS virus and its point ...Fish and chips: A fast track to understanding blood development
...ied to other disciplines, such as neuroscience and diabetes research. Citation: Eckfeldt CE, Mendenhall EM, Flynn CM, Wang TF, Pickart MA, et al. (2005) Functional analysis of human hematopoietic stem cell gene expression using zebrafish. PLoS Biol 3(8): e254. ...Studies on human genome variation provide insight into disease
... of improving diagnosis of common diseases such as diabetes and heart disease," says Cardon, "but the genome is tricky; it won't reveal its secrets easily. The real disease-causing culprits can have many silent partners. We need to know the relationships of all these partners to focus on real disease mutati...Housecat-sized Siberian tiger cubs get collared
... of improving diagnosis of common diseases such as diabetes and heart disease," says Cardon, "but the genome is tricky; it won't reveal its secrets easily. The real disease-causing culprits can have many silent partners. We need to know the relationships of all these partners to focus on real disease mutati...Toasty oat aroma influenced by presence of health-linked polyphenols
...rocess, in tanning, hardening of the arteries, and diabetes as well as other diseases. "The polyphenols' abi...rocess, in tanning, hardening of the arteries, and diabetes as well as other diseases. "The polyphenols' ability to quench sugars and inhibit the Maillard rea...Chemical compound inhibits tumor growth, size in new mouse study
...rocess, in tanning, hardening of the arteries, and diabetes as well as other diseases. "The polyphenols' abi...rocess, in tanning, hardening of the arteries, and diabetes as well as other diseases. "The polyphenols' ability to quench sugars and inhibit the Maillard rea...Scientists pinpoint inflammation gene
...hern European ancestry and has a high incidence of diabetes and obesity. Scientists worked with 522 individu...-sponsored study on the genetics of heart disease, diabetes and obesity in 1,400 Mexican Americans from 90 San Antonio families. Researchers studied an additi......eir potential use in humans to treat diseases like diabetes and Parkinson's is controversial because currently the only source of such cells for research is human embryos or mouse cells. Recently another research team published results showing that mouse male germ stem cells could be made to exhibit pluripote...