Virus-host interactions at sea effect global photosynthesis
...ael Waters, Ph.D., assistant director for database development of the NCT. "The availability of these sequences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality toxicogenomics data sets publicly available." The microarray......oning. It added, however, it does not prohibit the development of cell and tissue-based therapies based on research involving cloning technology to produce DNA molecules, organs, plants, tissues, cells (other than human embryos), or animals (other than humans).They believe that nations should "actively pursue th...B-15A collides with Antarctic ice tongue
...ael Waters, Ph.D., assistant director for database development of the NCT. "The availability of these sequences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality toxicogenomics data sets publicly available." The microarray...Biochemists report discovery of structure of major piece of telomerase; implications for cancer
...causing it, telomerase is an attractive target for development of anti-cancer drugs by pharmaceutical companies. The research, which was federally funded by the National Science Foundation and the National Institutes of Health, could have applications for many kinds of cancers. The domain of telomerase whose s...NYU and MSKCC research provides model for understanding chemically induced cancer initiation
...whether these lesions ultimately contribute to the development of lung and other cancers. ...Plant Sacrifices Cells to Fight Invaders
...cesses including immune system function, embryonic development and elimination of defective cells. When PCD malfunctions, or is undermined by pathogens, the effects can be devastating, resulting in diseases such as cancer, Alzheimer's and AIDS. Dinesh-Kumar, whose work is supported by the National Science Found...Scientists discover that three overlapping signals in embryo help get the backbone right
A major step in the development of the vertebrate embryo - the establishment of a ...the way biologists think about embryonic and fetal development and set the stage for the stem cell debate. That 1924 observation in newts by Hans Spemann and Hild...Marine sponge yields nanoscale secrets
...he biological world into practical methods for the development of new materials in the laboratory. The research ...tists are already taking the next steps toward the development of practical new and useful methods of nanoscale production by incorporating catalytic components on...Friendly bacteria in humans may protect against HIV
...ectively and safely." "The major roadblock in the development of this technology is the lack of financial support. Drug companies and venture capitalists are not interested because the beneficiary populations are infants and women in poor countries," says Tao. He is currently seeking sponsorship from charities ...Compounds in plastic packaging act as environmental estrogens altering breast genes
... the organ. "Estrogenic agents involved in breast development and possibly in breast cancer may include foreign estrogens, or xenoestrogens, that are used in manufacturing a number of products. The studies of BPA and BBP in young rats were designed to see whether exposure to these hormonally active biological c...UCSD research reveals mechanism involved with type of fatal epilepsy
...(PNAS). Lafora disease is characterized by normal development for the first decade of life, followed by an initial seizure in the second decade, progressively worsening seizures, early dementia, and death within 10 years of onset. Medications can ease the severity of initial symptoms, but there is no long-term ...Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia
...pril issue of Cancer Cell, is likely to facilitate development of new strategies to combat drug resistance and treatment failure for children with ALL. Nearly 80% of children with ALL are cured following chemotherapeutic treatment. However, the remaining 20% often exhibit drug resistance and treatment failure t...Protein Discovery Could Unlock The Secret To Better TB Treatment
...iscovery of Rpf in the TB bacteria could allow the development of methods to 'wake-up' all dormant bacteria in a patient allowing antibiotics to kill the bacteria and cure the disease." The team includes Prof Brian Henderson at the UCL Eastman Dental Institute, Nicholas Keep from Birkbeck, University of London,...NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
...nes and common nutritional and medicinal agents in development of cancer in the intestines. The drug they tested, sulindac, was a highly effective chemoprevention agent, the researchers say, because it worked to induce expression of the p21 gene, which they found put a firm stop on tumor formation even though t...Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol
...rous cellular pathways that are involved in cancer development and progression, the researchers say. Before thes... solid preclinical evidence that we can use toward development of a novel device that can measure CDK activity in human tissue within several hours," Ueno says. He......opment Agreement (CRADA) with NCI for the clinical development of bevacizumab. The Data Monitoring Committee overseeing the trial (known as E2100)* recommended that the results of a recent interim analysis be made public because the study had met its primary endpoint of increasing progression-free survival (the...Study reveals candidate targets for anti-retroviral therapeutics
...ike elements in yeast, will ultimately lead to the development of a new generation of anti-retroviral therapeutics. ...Product improves peptide identification for proteomics research
...standing of diseases like cancer and speeding drug development efforts. The Agilent 1100 Series LC/MSD Trap XCT Ultra offers significantly improved scan cycle times, enabling collection of mass spectra at rates up to three times faster than its predecessors. "The combination of the new LC/MSD Trap XCT Ultra wit...Supercomputers to focus brains on AIDS dilemma
...HIV/AIDS, the Merck scientists are proceeding with development of a series of drug candidates that rely on the re...al sites. The Merck scientists have chosen a drug development strategy in which they are developing "single wing" compounds, whose wings, or cyclic moieties, can ...Disease progression model of pancreatic cancer developed by Penn researchers
...t not all pancreatic cancers are equivalent." The development of the first animal model for pancreatic cancer that fully imitates the progression of the human condition will likely open many new doors in understanding this debilitating disease. "With a model that can generate the full spectrum of disease, from ...