Bioelectronic ‘signatures?hold key to DNA mutations
...atents to his credit, including involvement in the development of the first noninvasive biosensor for diabetes, the FDA approved Gluco Watch, which monitors glucose levels through human sweat. “The ultimate goal is to make something similar to a hand-held glucose monitor for future genetic testing,?Wang says. “...Researchers unlock mechanism creating jigsaw puzzle-like plant cells
...these distinct signals play a critical role in the development of leaf cell walls and leaf structures in a controlled and ordered way and that genetically over expressing one or the other leads to cells lacking the interlocking jigsaw puzzle appearance. While the researchers unlocked a fascinating mechanism of ...New understanding of DNA repair may pave way to cancer treatments
...the finding that ATF2 has an important role in the development and progression of melanoma tumors. Inhibition of ...mic the peptide's actions and to allow for further development of the peptide toward clinical assessment. "Until our recent studies, we were certain that the mech...Cerebral navigation: How do nerve fibers know what direction to grow in?
Nervous system development requires billions of neurons to migrate to the app...e've uncovered could provide opportunities for the development of therapies for spinal cord injury, targeting ephexin and possibly Vav," he speculates, "but much m...Global analysis of membrane proteins
...is important for scientists working in, e.g., drug development who often need access to large amounts of purified membrane proteins. Large-scale projects where scientists from different fields work together are becoming increasingly common in biology. The new study has been made possible through a close collabo...Brain-injury rehabilitation depends on acetylcholine circuitry
...on to recover from such injuries by leading to the development of drugs or other treatments to enhance the "cholinergic system." The researchers said that their finding that the cholinergic system is involved in brain recovery is particularly intriguing in light of the fact that deficits in the system have been...Roche clinical trial registry and results database launched
...h ethical standards in Roche’s clinical trials and development activities. In addition, Roche adheres to the “Declaration of Helsinki? a statement developed by the World Medical Association on ethical principles to provide guidance to physicians and other participants in medical research involving human subjects...New tumor-suppressor gene discovered
...how tissue growth is controlled both during normal development and during the formation of tumors, and it raises ...for normal differentiation of eye cells during the development of the fly's eye. Lai's team also tackled the tough challenge of discovering how the mats gene is a...First technology to remove prions that cause vCJD from blood launched
... health. Pall is continuing its prion research and development program to apply its technologies to meet the specific requirements of each nation throughout Europe, followed by Canada and the US. The Company is also developing an ante mortem test to detect infectious prions in cattle prior to entering the food s...FDA Works To Speed The Advent Of New, More Effective Personalized Medicines
As part of an agency-wide initiative to speed development of new medical products through the science of pha...cation or regimen. This technology has enabled the development of targeted therapies like Herceptin for metastatic breast cancer, Gleevec for chronic myeloid leuke...Turning viruses into allies against cancer
..., this version of OncoVEX is now entering Phase II development in a number of tumor types." The study's principal investigator was Charles Coombes, M.D., Ph.D., who heads the Cancer Research (UK) Laboratories and a professor at Hammersmith Hospital, part of Imperial College, where many of the patients in the st...Mouse gene shows new mechanism behind cardiac infarction in man
...ng human gene has been shown to play a role in the development of myocardial infarction. The results of the stud...mosome 1 that is of demonstrable importance to the development of arteriosclerosis. The TNFSF4 gene was identified as the one responsible, as mice with mutations i...... and Proteome Systems will also collaborate on the development of applications and seminars as part of the marketing agreement. "Agilent is proud of this collaboration with Proteome Systems," said Taia Ergueta, general manager of Agilent's Proteomics and LC/MS business. "It illustrates our ongoing commitment to...At long last, scientists figure out how plants grow
... known of its dramatic effects on plant growth and development since the 1930s. But only now do scientists know how it works. In this week's Nature, Indiana University Bloomington biologists Mark Estelle, Nihal Dharmasiri and Sunethra Dharmasiri identify TIR1 as the protein that, with auxin, influences how and ...Roots Engage in Underground Chemical Warfare
...d (CAREER). CAREER awards support the early career development of those researcher-educators who are deemed most likely to become the academic leaders of the 21st century. Parag Chitnis, the NSF program manager of Vivanco's award said, "This work is an exciting outcome of a bold and challenging project. The work...What's really making you sick? Plant pathologists offer the science behind Sick Building Syndrome
...ologists to study building-related mold growth and development and SBS syndrome in real-world conditions. More on this topic will be presented during the Identification of Fungi Involved in Sick Building Syndrome workshop at the APS Annual Meeting in Austin, TX, July 30 - August 3, 2005. The workshop will offer...MUHC scientists describe genetic resistance to rampant virus
...ure Genetics last week, provides a roadmap for the development of human therapies for CMV, which could prolong the life of HIV patients and improve the success of transplant surgery by reducing the risk of rejection. There is currently no treatment or cure for CMV. Resistance to diseases like CMV depends, at le......ng because we expect to make breakthroughs in diet development and growout of juveniles that will help to make the culture of this species a reality, " she said. Spiny lobster is an ideal target for commercial culture due to its high value and limited availability from wild capture, mostly using traps. Each yea......ael Waters, Ph.D., assistant director for database development of the NCT. "The availability of these sequences will be of great benefit to the microarray bioinformatics community and to databases such as the NCT's CEBS as we seek to make high-quality toxicogenomics data sets publicly available." The microarray...