development 2 7

Tag: "development" at biology news

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

... ball. A new approach to predict whether a drug in development is likely to work and which dose is best could get... to inefficiencies in the drug and medical product development process, urging changes to make the process “more predictable and less costly.?The latest estimates ...

Light therapy may combat fungal infections, new evidence suggests

...e of environmental signals such as light in fungal development is vital to increase the benefits and decrease the costs that fungi present." The researchers first tested the importance of genes with known roles in light sensitivity of another, distantly related fungus. Yeast strains lacking one of those genes, ...

Gene therapy promising for growing tooth-supporting bone

... studies have shown that BMPs are present in tooth development and periodontal repair. This study mixed BMP-7 genes with an inactivated virus in a gel-like carrier and injected it into wounds. Giannobile said using a virus, with the harmful effects turned off, harnesses the virus' ability to enter into cells an...

Researchers find new genes necessary to make embryo

...at at least 2,600 genes are required for embryonic development in C. elegans, of which about 70% are currently known. The majority of genes required for embryogenesis in C. elegans have counterparts in humans whose roles are often unknown. For example, human counterparts of four of the newly identified genes ar...

UCSD-Salk Team Show Protein’s Gene-Silencing Role In Development of Nervous System

...roteins called phosphatases play a key role in the development of the nervous system, has been shown in fruit flies and mice by researchers at the University of California, San Diego (UCSD) School of Medicine, in collaboration with scientists at the Salk Institute, La Jolla, California. The phosphatases are requ...

Promising new West Nile therapy cures disease in mice

...ibody in mice and say its success warrants further development and testing in people with West Nile disease. "West Nile virus has emerged in the United States as a regular seasonal threat, particularly for people over 50. We currently do not have a proven therapy for people with serious West Nile disease, so we...

Scientists identify molecule that regulates well-known tumor suppressor

... for cancer patients and be useful as a target for development of future cancer therapeutics. Interestingly, DJ-1 may play a role in other disease states, as it has also been recently identified as a predictive diagnostic for early-onset, autosomal recessive Parkinson's disease. The other members of the researc...

Microbial forensics: The next great forensic challenge

... S. Murch, associate director for research program development at Virginia Tech, formerly deputy director of the FBI's Laboratory and Investigative Technology Divisions and a research staff member at the Institute for Defense Analysis. Murch created the FBI's weapons of mass destruction forensic unit in 1996 and...

Newly discovered pathway might help in design of cancer drugs

...oduce, a finding that could eventually lead to the development of new anti-cancer drugs and therapies. The method could enable future doctors to target treatment more precisely, rather than directing chemotherapeutic medication or radiation to tumors through a scattershot approach, said Marc Greenberg, a chemis...

Anti cancer virotherapy well tolerated in first human administration, research finds

... for treatment of a range of cancers. Research and development is currently at preclinical stage, progressing to Phase I clinical trials in 2005. Initial clinical trials will be on melanoma and ovarian cancer. More information is available at www.psiron.com ...

Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive

...I would speculate that autism involves an atypical development of the midbrain and basal ganglia reward systems. This makes sense, too, because other symptoms of autism include repetitive thoughts and movements, characteristics of basal ganglia function. " Surprise discovery: romance is on the right, 'attractiv...

Researchers make gains in understanding antibiotic resistance

...biotic resistance are already being applied to the development of new antibiotics. One company leading the way is Rib-X Pharmaceuticals, which was founded by Steitz and colleagues at Yale. "About half of current antibiotics target the ribosome, and most of them target the large subunit," he said. "So, such advan...

Harmful chemicals may reprogram gene response to estrogen

...e data suggest that environmental exposures during development of the uterus can interact with a preexisting gene...e DES exposure enabled estrogen to drive the tumor development when combined with a genetic predisposition." While DES exposure can lead to the development of vag...

Solutions that reduce death of marine life reeled in by International Smart Gear Competition

..." said grand prize winner Steve Beverly, fisheries development officer for the Secretariat of the Pacific Community. "It's just common sense to create smarter fishing gear." An international panel of expert judges unanimously awarded the grand prize and $25,000 to Beverly, an American working in New Caledonia a...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

... process is extremely important during the initial development of the blood system before birth. Expression of Mc1-1 is also crucial for maintaining blood cells throughout life as red and white cells and platelets die and must be replaced. HSCs are also needed to rebuild the blood system of patients undergoing c...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...called Krabbe disease can be saved and their brain development preserved if they receive stem cells from umbilica... assessed the neurological, cognitive and physical development of each child with Krabbe Disease before and after transplant. Escolar is lead author of the study ...

Defenseless plants arm themselves with metals

... of these plants and may have implications for the development of crops that may one day remove metal and other contaminants from the environment. "Our goal is to find the high-level regulator - the one gene or group of genes that turns a plant into a hyperaccumulator," said David Salt, associate professor of p...

New Estimates For The Causes Of Child Deaths Worldwide

...sor Black comments: "Achievement of the millennium development goals of reducing child mortality by two-thirds from the 1990 rate will depend on renewed efforts to prevent and control pneumonia, diarrhoea, and undernutrition in all WHO regions, and malaria in the Africa region. In all regions, deaths in the neon...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

... control neutrophil turnover may contribute to the development of future therapeutics for conditions characterized by abnormal numbers of these critical immune cells. Human neutrophils are white blood cells that are constantly being produced in the bone marrow and released into the blood stream where they migra...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

...icant technical hurdles that have until now slowed development of NK-based therapies for ALL, according to Dario ...y breakthroughs made by the St. Jude team were the development of a laboratory technique for rapidly producing a large, pure population of NK cells from a small sa...

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