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Tag: "development" at biology news

Key molecule in plant photo-protection identified

...id clearance of brain plaques,made possible by the development of Abeta antibodies, affect theprogression of Alzh... would halt the progression of thedamage--stop the development of new swellings," says Brendza. "But whatwe saw was much more striking: in just three days, there w...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...hers found that Pax3, a gene critical in embryonic development of melanocytes ?cells that make and store the pigments in the skin and hair ?is also expressed in adult stem cells in the skin. "Our findings told us that a recapitulation of an embryonic program is occurring in resident stem cells in adult skin," e...

Plants, animals share molecular growth mechanisms

...e genes and their proteins are required for normal development and for normal cell-to-cell adhesion," Szymanski s...s DIS3 or the whole WAVE complex." For growth and development biochemical processes to proceed normally, activators such as ARP 2/3 are needed to trigger actin fi...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...ro, Genova, Italia). "Previous theories about the development and progression of chronic lymphocytic leukemia require revision. With new molecular and protein markers now identified, patients with features that portend poor outcomes may soon be treated earlier and more effectively," said Dr. Chiorazzi. "Once t...

Scientists detect probable genetic cause of some Parkinson's disease cases

... fresh evidence that genetics maycontribute to the development of some cases of Parkinson's disease. Thefindings could lead to the development of a genetic test to detect themutation in individuals at risk. The research team includesinvestigat...

Computers to be used to find blueprint for new influenza drug

...illiams said that his work is a more sophisticated development from similar modelling which produced two anti-influenza drugs, Relenza and Tamiflu, whose effectiveness is limited. He and Dr Ruggiero will study sialidases, enzymes used by the flu virus to snip off a special type of sugar, sialic acid, from the t...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

...Aneurons. The authors observed increased DA neuron development andsubsequently transplanted these neurons into monkeys treated with anagent called MPTP, which is considered a primate model for Parkinsondisease. These transplanted cells were able to function as DA neuronsand diminished Parkinsonian symptoms.In an...

A much-needed shot in the arm for HIV vaccine development

...at the Global HIV VaccineEnterprise will speed the development of a vaccine by bringing newcollaboration, resourc...ntific strategic plan will not only accelerate the development of alifesaving HIV vaccine but also boost African capacity in healthresearch to address new health t...

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...ential benefits, as syntheticgenes could allow for development and production of safer, less toxicproteins that a...iral diseases. Thistechnology also will facilitate development of new medications throughthe creation of humanized yet synthetic antibodies that could beespecially...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...protease inhibitors may, in fact, be linked to the development of heart rhythm problems through the mechanism of blocking a channel. Ultimately researchers from the University of Wisconsin led by Craig January, M.D., Ph.D., discovered that protease inhibitors do block these key channels. "Our findings suggest t...

“Nano-scissors?laser shows precise surgical capability

...ering atThe University of Texas at Austin, led the development of thetechnique. It acts like a pair of tiny “nano-scissors,?able to cut,for example, nano-sized units like nerve axons, the parts of nervecells that carry nerve impulses away from the cells to muscles or toother cells.“This tool opens up a new front...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

There's aparadigm in life science and drug development : only "lucrative""markets" get exploited by R&D companies. In many occasions I'veseen very promising drugs candidates or related research get cannedbecause no money was to be made with it, even if millions would havebeen saved worldwide. The usu...

Genome-wide mouse study yields link to human leukemia

... and a unique chemical signature implicated in the development of human leukemia, findings that open up a "treasu...e model as a good predictor of what happens in the development of human disease," he added. The findings appear in Nature Genetics online at http://www.nature.com...

Cytoplasm affects the number of vertebrae in carp-goldfish clones

... so-called "segmentation clock" early in embryonic development is controlled by the egg cytoplasm. Thus the egg c...of the nucleus and egg cytoplasm to the growth and development of vertebrates. ...

Breakthrough Microarray-based Technology for the Study of Cancer

A new development in the analysis of cancerhas been announced by Agilent Technologies. The company has reported aninnovative method that enables the rapid advance of microarray-basedcomparative genomic studies in cancer. According to the reportpublished in the Decembe...

Learning to fight an adversary that won't stay down

...igh throughput screening were expected to make the development of new antibiotic compounds easier and more productive. But in most cases the microbes continue to hold the upper hand ?and if three billion years of bacterial history is any kind of track record, we're in for an endless running battle, says Dr. Juli...

Found: Missing sequence of the human Y chromosome

..., or gonadoblastoma locus, whichis responsible for development of tumors associated with theundifferentiated gonad, has been genetically mapped to the region.Because the "missing" sequence described in this study contained eightputatively active genes, further functional testing of these genes mayreveal insights...

Mitochondrial DNA mutations play significant role in prostate cancer

...chondrial DNA (mtDNA) playan important role in the development of prostate cancer, according toresearch by scientists at Emory University School of Medicine and theUniversity of California, Irvine. The findings are published onlinethis week in the Proceedings of the National Academy of Sciences(PNAS). Mitochondr...

Gene therapy converts dead bone graft to new, living tissue

... the foreign splint as living bone, is a promising development for the thousands of cancer and trauma patients ea...ertzman, executive vice president for research and development at the Musculoskeletal Transplant Foundation. Other scientists have attempted to invoke a similar r...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...xplain how exposure to BCE affectshuman nerve cell development and how it might relate to neurologicaldisorders. ...ering neural development,and alterations in neural development are thought to be a cause ofautism," says Jill Kreiling, first author of the paper and a member ofRe...

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