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Tag: "development" at biology news

Researchers make surprise discovery that some neurons can transmit three signals at once

...NMDA receptors at the most critical stage of brain development and organization, we realized that this could explain a number of fundamental questions," explained Karl Kandler, Ph.D., associate professor of neurobiology at the University of Pittsburgh School of Medicine, and the study's senior author. "These fi...

Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma

...ely lead to increased knowledge of the origins and development of this and other cancers. "Agilent's CGH technology will allow us to study the entire genome in a manner that hasn't been possible in previous genomics research," said Holloway. "Upon completion, this project will produce the largest data set of it...

Scientists discover how Ebola virus infects cells

...nhibitors of cathepsins are already under clinical development as anti-cancer drugs. The authors write, "Further ...vo pharmacology of these inhibitors may facilitate development of an anti-Ebola-virus therapy." Reference: K Chandran et al. Endosomal proteolysis of the Ebola vi...

Master gene controls healing of skin in fruit flies and mammals

...discovered that the genetic system controlling the development and repair of insect cuticle--the outer layer of t... grainyhead gene is also essential for normal skin development and wound repair in mice. "The discovery that grainyhead-like factors are required for the response...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

...called Krabbe Disease can be saved and their brain development preserved if they receive stem cells from umbilica... assessed the neurological, cognitive and physical development of each child with Krabbe Disease before and after transplant. Escolar is lead author of the study ...

Gene keeps neural cells on correct developmental path

... ensemble of genes that coordinates nervous system development by removing REST in three distinct phases, ending with shutting down the REST gene. "The cell gets rid of all the excess protein, kicks it off the DNA, then stomps on its head so it can't make RNA," Mandel said. "We can't detect REST in the terminal...

Designing vaccines by computer

...t the increasing role of computer modelling in the development of new vaccines could bring new products onto the ...e using a very simple concept to help speed up the development of vaccines. They are studying fragments of 'foreign' proteins that have been shown by experiments t...

Scientists generate patient-specific stem cells, Science study says

...one case, the same person), the researchers report development of 31 hollow balls of cells called "human nuclear-...stems indicate that serious abnormalities in human development would result if the cells were used in reproductive cloning. Any attempts at reproductive cloning wo...

SuperLigands - a database of ligand structures derived from the Protein Data Bank

...one case, the same person), the researchers report development of 31 hollow balls of cells called "human nuclear-...stems indicate that serious abnormalities in human development would result if the cells were used in reproductive cloning. Any attempts at reproductive cloning wo...

Mouse with designer liver has enhanced glucose tolerance, insulin response

...resistance in the liver is a crucial factor in the development of hyperglycemia and hypertriglyceridemia in indiv...ries by Burnham scientists have contributed to the development of new drugs for Alzheimer’s disease, heart disease and several forms of cancer. Today the Burnham I...

Microscopes at microscopic size

...arger than a single cell that could lead to faster development of new drugs and quicker medical tests. The resea..."The success of the research into biochips and the development of the science through the spin-out company shows how cutting edge research in the biosciences can m...

Structure-building cell signals also may influence learning and memory

...s, called ephrins, which are known to regulate the development of nerve cells, also controls nerve cells' ability to engulf critical chemicals and proteins for learning and memory. These findings, the first to link these molecular semaphores to this important nerve cell function, appear in the May issue of Natur...

Wake Forest scientists find new combination vaccine effective against plague

...alth under a federal bioterrorism initiative. "The development of a vaccine against the pneumonic or respiratory form of plague is a major goal of the bio-defense initiative," he said. The research program involves six other medical school scientists and a secure biosafety laboratory at Virginia Tech that is ce...

15-year hunt finds cause of pseudothalidomide syndrome

...lls tend to stop growing or die, precluding proper development of the limbs, palate and other structures. The researchers were funded by the Japanese Ministry of Education, Culture, Sports, Science and Technology; the Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnologia; the Smile Train Fellows...

Prescription Drug Patches Gaining Ground, Tackling New Therapies

... host of new conditions wind their way through the development and clinical trial process. Growth in demand for prescription drug patches is being driven by several factors ?factors with strong demographic and population trend underpinnings. Technology has also played a major role in prescription patch growth. ...

Comprehensive biodefense text published

...ures, emerging threats and future preparation, and development of diagnostic tests for identifying biological warfare pathogens. Intended for researchers, physicians, and policy makers, Biological Weapons Defense: Infectious Disease and Counterbioterrorism offers a detailed look at the ongoing efforts to detect ...

TrueBlue Archive Will Store Raw Life Sciences Data for Proteomics and Drug Testing

...ures, emerging threats and future preparation, and development of diagnostic tests for identifying biological warfare pathogens. Intended for researchers, physicians, and policy makers, Biological Weapons Defense: Infectious Disease and Counterbioterrorism offers a detailed look at the ongoing efforts to detect ...

Gov't Creates Gene Database of Normal Human Tissues

...r with the kinds of activities associated with the development of cancer -- processes such as apoptosis, growth, proliferation and transcription," said Khan. These results provide scientists studying and treating NB with a focused set of genes to explore. ...

Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage

...o become a gamma-delta T cell." Understanding the development of critical components of the immune system can lead to scientific and medical advances in stimulating desirable immune responses and halting unwanted ones. "Although their precise function is still unclear, delta-gamma T cells seem to form the firs...

NHGRI targets 12 more organisms for genome sequencing

... into model organisms utilized in research on drug development and disease susceptibility. They are: sequencing t...portant innovations in animal anatomy, physiology, development or behavior. The organisms are: a skate (Raja erinacea); a sea slug (Aplysia californica); a disease...

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