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Tag: "developing" at biology news

Wisconsin scientists grow critical nerve cells

...e of the earliest neural structures to emerge in a developing embryo. With the ticking clock of development in mind, Zhang and his team deduced that there is only a thin sliver of time - roughly the third and fourth week of human development - in which stem cells could be successfully prodded to transform thems...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...so suggest that this enzymesystem may be useful in developing preventative therapies against skincancer. Ultraviolet light is a knownsource of damage to our DNA, but under normal conditions humans andother mammals are capable of removing UV-induced DNA damage by a DNArepair mechanism called nucleotide excision...

W.M. Keck Foundation funds study of friendly microbes

...ving to culture them in test tubes. They are also developing new computational methods for mining genome sequence data so that bacterial species can be more rapidly and accurately classified. A large publicly accessible database will be established that provides detailed molecular information about the gut eco...

Columbia research lifts major hurdle to gene therapy for cancer

...rs.Dr. Fisher's team is now altering the virus and developing additionalviruses based on the PEG switch for use in clinical trials withpatients. Other investigators associated with the PNAS study includeDrs. Zao-zhong Su (research scientist), Devanand Sarkar (associateresearch scientist) and Luni Emdad (postdoc...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...nts with low birth weight have a high potential of developing type 2 diabetes later in life. In studies of mice,...nited States," she added. "But poor nutrition of a developing baby can occur in many ways other than inadequate nutrition of the mother. It also can occur with ab...

Fox Chase Cancer Center scientists identify immune-system mutation

...he genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T...en the normal form of this factor is active in all developing lymphocytes, it can redirect would-be killer cells to the CD4 helper T cell lineage. This indicates ...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...ca, a leading cause of severe diarrheal disease in developing countries, includes an unexpectedly complex repert...infections are one of the major health problems in developing countries and the number of people who are infected with amoeba cysts is enormous," he says. Typica...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...reviously had only been known to be expressed in a developing embryo. That was the first clue that we were on to...g stem cell biology may therefore be important for developing new therapies for cancer. Adult resident stem cells have been identified in many types of organs an...

Computers to be used to find blueprint for new influenza drug

...e when fears are rising that an influenza outbreak developing from Asian chickens could kill thousands of people. Professor Ian Williams, of the Department of Chemistry, will begin work in April on a project that could help pharmaceutical companies develop a better drug that could be taken by people coming dow...

Ecological destruction fuels emerging diseases

...ational scientific and economic initiative to help developing countries preserve the world's biodiversity. In the Guanacaste Conservation Area of northwest Costa Rica, a 1,000 square km (400 square mile) United Nations World Heritage Site that features habitats ranging from rain forests to savannas, the ATBI i...

A much-needed shot in the arm for HIV vaccine development

International efforts towards developing avaccine against HIV infection have been given a m...tly accelerate progress toward the critical goalof developing a safe and effective HIV vaccine to help curb the globalHIV/AIDS pandemic.""Being from the continent...

Breakthrough Microarray-based Technology for the Study of Cancer

... key tounderstanding cancer progression as well as developing possibletherapies and prognostic and diagnostic tools."Genomic alterations leading to changes in the number of gene copiespresent in cells are important events in the genesis and progression ofcancer," said Michael Bittner of the Translational Genomi...

Live Recombinant Adenovirus Vaccine Technique Explored

...e particularly beneficial for people living in the developing countries where resources are limited. Their resea...man papillomavirus (HPV) that could be used in the developing world. HPV causes 500,000 cases of cervical cancer each year worldwide. Recombinant HPV vaccines cur...

Mitochondrial DNA mutations play significant role in prostate cancer

...fthe mitochondrial DNA are at an increased risk of developing prostatecancer later in life. Interestingly, mitochondrial DNA is inheritedfrom your mother, so this may explain those familial cases that are notpassed from father to son, but rather through the unaffected mother toher sons."...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...scientist Carol Reinisch and her colleaguestreated developing surf clam embryos (Spisula solidissima) withdiffer...ertilized them in vitro, and added BCE to normally developing clamembryos. The investigators used a combination of antibodies and dyes toshow the presence of neur...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

...scientist Carol Reinisch and her colleaguestreated developing surf clam embryos (Spisula solidissima) withdiffer...ertilized them in vitro, and added BCE to normally developing clamembryos. The investigators used a combination of antibodies and dyes toshow the presence of neur...

Spider Venom Could Yield Eco-Friendly Insecticides

...ust a few minutes. King and his colleagues are now developing both engineered viruses and small-molecule mimics of the toxins in preparation for field trials. The Blue Mountains funnel-web spider is not the only source of insect-specific neurotoxins. Thousands of spider species yet to be studied represent an u...

BRCA1 causes ovarian cancer through indirect, biochemical route

...riers of its mutated form a four in five chance of developing breast cancer, it also confers a 40 percent risk of developing ovarian cancer by the age of 70. How that risk is imparted, however, had been harder to pin down. "...

Scientists decipher genome of fungus that can cause life-threatening infections

... sometimes involves a fatal brain inflammation."In developing countries, cryptococcosis has emerged as one of the mostcommon opportunistic infections, and a leading cause of meningitis andbloodstream infection," says Joseph Heitman, a senior communitycollaborator on the project who is James B. Duke Professor of...

Purdue proves concept of using nano-materials for drug discovery

...otherapy drugs more effective. The researchers are developing synthetic cell membranes to mimic the real thing and then plan to use those membranes to create chips containing up to 1 million test chambers. Each chamber would be covered with a membrane containing the proteins, and the chambers could then be used...

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