Ancient amphibians evolved a bite before migrating to dry land
Ancient aquatic amphibians developed the ability to feed on land before completing the transition to terrestrial life, researchers from Harvard University report this week in the Proceedings of the National Academy of Sciences. Their work is based on analysis of the skulls of the first...Surgeons develop simpler way to cure atrial fibrillation
...on University School of Medicine in St. Louis have developed and tested a device that radically shortens and si...like a bag of worms. The Cox-maze procedure was developed at the University in 1987. In their latest clinical study, reported in the February issue of the Jou...New cell type identified in cancer development
...mune systems, however. In those animals, the pCSCs developed into solid tumors, developing additional mutations in different cell types as they grew and spread. Additional experiments revealed that the piwil2 gene may exclusively regulate the process of pCSC development. Gao says these data suggest...Ebola outbreaks killing thousands of gorillas and chimpanzees
... social groups. The study provides hope that newly developed vaccines could control the devastating impact of Ebola on wild apes. Direct encounters between gorilla or chimpanzee social groups are rare. Therefore, when reports of large ape die-offs first surfaced in the late 1990s, outbreak amplification was ...Protein overexpression at heart of heart failure
...L-VDCC characteristics was proven when the authors developed a novel, cardiac-specific, drug-inducible beta 2a subunit overexpression transgenic mouse which was crossbred with the channel pore overexpressing mouse when still nonfailing (“Adaptive phase?. In the nonfailing double transgenics, the induction of b...Elucidation of the genome for diabetics with DNA chips
...06, a revolutionary genetic analysis technique was developed in the United States. This method is based on the use of DNA chips, with a surface of only a few square centimetres, carrying almost half a million DNA mutations. Each of these chips can be used to dissect the entire genome of an individual. Ini...Protein discovery targets antibiotic-resistant bacteria
...ponsible for typhoid fever ?a huge problem in less developed countries ?the model being developed at Queen’s could potentially be a target for treating typhoid as well. The underlying goal is to con...Study to explore using magnets to correct 'sunken chest'
...mes more common in boys than girls. A UCSF team developed the new procedure, in which a magnet attached to the child's breastbone is coupled with a second one outside the chest that creates a steady, controlled, outward pull on the internal magnet to reshape the bone, cartilage and chest wall. The proce...Instruction manual for creating a molecular nose
...ive structure," says Sinner. The new procedure developed by Eva-Kathrin Sinner and her research group makes it possible, for the first time, to examine the natural functions of such membrane proteins in situ. This is of considerable importance to pharmaceuticals research, as it means that new active agent ...Cancer vaccines -- Taking a jab at cancer by stimulating the immune system
... phase II trial of a human papillomavirus vaccine, developed to prevent cervical cancer, shows that the vaccine...h and the Gunma University School of Medicine have developed a vaccine that enlists multiple parts of the immune system into targeting p53 in head and neck squam......ands of years ago. The result suggests chimpanzees developed this behaviour on their own, or even that stone tool use was a trait inherited from our common ancestor. Julio Mercader, Christophe Boesch and colleagues found the stones at the Noulo site in Cote d'Ivoire, the only known prehistoric chimpanzee settl...Bioluminescence at the service of a novel cerebral imaging technique
CNRS scientists in collaboration have developed a new technique for the in vivo imaging of neuronal function using bioluminescence, based on a GFP-aequorin fusion protein. This imaging technique enables the monitoring of neuronal activity (and more specifically, calcium activity), real-time and in...Researchers from the UGR use a bacterium to obtain biopreservatives from food
... Over the course of evolution, microorganisms have developed several strategies to compete for nutrients in their environment. One of these strategies is to produce antimicrobial compounds such as antibiotics, certain metabolism products, lytic agents, numerous types of protein exotoxins, and bacteriocins. It ...Large size crucial for Amazon forest reserves
... authors used state of the art statistical methods developed by James Nichols and colleagues, at the U.S. Geological Survey's Patuxent Wildlife Research Center. "With a handle on the detection problem it is much easier to understand real species occurrence", said Nichols, "and looking at occurrence through ...New study may show how to forestall a fatal, virus-caused immune-system meltdown
... now online, the scientists describe using a newly developed protein-scanning chip and a uniquely capable computer database to examine the activation and deactivation of more than a thousand proteins in cells from guinea pigs infected with two different strains of Pichinde virus. Guinea pigs infected with one ...Researchers urge monitoring of bone health during chemotherapy
...breast cancer cells into mice, those getting G-CSF developed a two-fold increase in tumor burden, a measure of the size and severity of tumors, compared to those that did not receive G-CSF. Interestingly, mice treated with a bisphosphonate, an anti-osteoporosis agent that inhibits osteoclasts, were resistant ...Hofmeyr skull supports the 'Out of Africa' theory
...e apparent only recently. A new approach to dating developed by Grine team member Richard Bailey and his colleagues at Oxford University allowed them to determined its age at just over 36,000 years ago by measuring the amount of radiation that had been absorbed by sand grains that filled the inside of the skul...Researchers create artificial enzyme that mimics the body's internal engine
...ccording to Devaraj, the new laboratory techniques developed in this experiment may have applications for research involving other enzymes. Understanding what makes CcO so efficient in reducing oxygen to water may even be useful to the study of fuel cells-very efficient power sources that convert chemical ener...White blood cells in lung produce histamine seen in allergies
... wild-type mice. Both populations of infected mice developed pneumonia. "We thought the mice without mast cells would do better than the wild-type mice, because the infection wouldn't be provoking mast cells to release histamine," recalls Caughey. "In fact, they did much worse. Even though there were no mas......sed on these findings, Lundblad and her colleagues developed a model, which predicts that Cdc13, Stn1 and Ten1 come together at the very end of chromosomes to form a telomere-dedicated RPA-like complex they dubbed the t-RPA complex. Graduate student and first author Hua Gao tested this model, using detailed...