Application of Genomatix in silico methods reveals novel cancer associated genes
...associated genes, based on strategies and products developed and promoted by Genomatix. Experimental verification by siRNA knock-down and RT-PCR confirmed the in silico results. "I am delighted that an ever increasing number of scientists proof the validity of our concepts and experience the value of our inte...Researchers discover new details about HIV-1 entry and infection
...n Hladik and colleagues in the McElrath laboratory developed a unique model system to study the precise mechanisms by which HIV-1 enters the lower reproductive tract of human females. The researchers separated and removed the outer lining of vaginal cells, which serves as the first barrier to the virus. The is...Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer
...those cells. The FUS1 nanoparticle formulation was developed and tested in Roth's lab. It advanced to phase I clinical trial after a promising test on human non-small cell lung cancer in a mouse model. FUS1 was discovered by a research team led by Roth at M. D. Anderson and by John Minna, M.D., of the De...Computer scientists join in search for ivory-billed woodpecker
... ?in the animals' habitats. Song and Goldberg have developed robots to webcast images of animals from the animals' habitats to natural scientists' computers. In addition to the Cache River National Wildlife Refuge, they've installed one of their robots in the Richardson Bay Audubon Sanctuary in California...Stem cell transplants explored at Stanford as a possible treatment for hearing loss
...e that one in three adults over the age of 65 has developed a handicapping hearing loss. Coming up with the answers is a slow process, Heller said. "This research takes time and money, but we remain hopeful we'll have some principle answers soon." ...Swell gel could bring relief to back pain sufferers
...rom The Faculty of Medical and Human Sciences have developed tiny gel particles that swell and stiffen when inj.... The microgel particles the research team have developed are like 'smart sponges' when dispersed in water. The material is a fluid at a low pH - in other ......e natural scientists use concepts and technologies developed by engineers to try to understand what makes animals tick, certain computer scientists and engineers look to the natural world for inspiration and guidance as they build intelligent machines. Ongoing research has already produced some computer progra...Stopping plants from getting sick
...lant, meaning the right kind of fungicide might be developed to target that ability and block infection. "These pathogens provide us with the best of both worlds in terms of research ?we can study them in the field, but we can also bring them to the laboratory and isolate the genes that allow them to infect...Cancer researchers add spice to research against rare neuromuscular disease
...h needs to be done to see if the compound could be developed into a drug to help people with the disease, scientists say it's a promising development in a field where progress has been slow. The research by scientists at the University of Rochester Medical Center appears in the March 6 issue of the journal ...Lab research may one day lead to cancer treatment using patient's own immune cells
...ials prove successful, a similar approach could be developed in patients with other types of cancer as well," said Kim. ...Small molecule dervived from Rb2/p130 could act as cancer therapeutic
...ility to inhibit tumor growth in vivo and could be developed into an anti-cancer therapeutic, according to researchers at Temple University's Sbarro Institute for Cancer Research and Molecular Medicine. The researchers reported their findings, "A small molecule based on the pRb2/p130 spacer domain leads to in...Flavanols in cocoa may offer benefits to the brain
...bility that products utilizing this cocoa could be developed to help maintain healthy brain function throughout several life stages. More research examining the potential of this cocoa in this important area of public health need is clearly warranted.?/p> During the session entitled “The Neurobiology of...Susceptibility to Crohn's disease -- an important new clue
...t that affects an estimated 0.15% of people in the developed world. Common symptoms include abdominal pain and diarrhea, but the disorder is often associated with debilitating clinical complications. Researchers from the University of Liège, Belgium, have now uncovered an important clue to the susceptibility o...Health Canada approves cold and flu medicine
...gies, a University of Alberta spinoff company that developed COLD-fX. Shan, who is also president, CEO and Chief Scientific Officer of CV Technologies added, “There are two novel therapeutic aspects to COLD-fX. First, COLD-fX is one of the very few medicines ?drugs or natural health products ?that Health C...New sensor detects gaseous chemical weapon surrogates in 45 seconds
...hers at Pacific Northwest National Laboratory have developed a chemical weapon agent sensing technique that promises to meet or exceed current and emerging defense and homeland security chemical detection requirements. The technique, called Quartz Laser Photo-Acoustic Sensing, or "QPAS," is now ready for proto...Resistance to anti-HIV drugs in Uganda developed due to drug supply problems
...nt of people on treatment for 6 months. Resistance developed in people during treatment interruptions, and 90 percent of all missed doses were due to treatment interruptions as opposed to the occasional skipped dose. Further, almost 50 percent of the participants interrupted treatment due to financial difficu...Triplex assay used to assay duplex genomic DNA
...CR which has inherent problems and is costly. "We developed the heteropolymeric triplex assay step by step" sa...rted with synthetic 50-mer duplex targets and have developed our methods to the point where human genomic samples can be assayed." The assay uses YOYO-1, a bis-i...Buckyballs used as 'passkey' into cancer cells
... Barron. "Viruses, which are often toxic, long ago developed ways of sneaking through cell walls. While we're m...sskey." The passkeys that Barron and colleagues developed contain a molecule called Bucky amino acid that was created in Barron's lab. Bucky amino acid, or Ba...New test for most virulent HPV strains under study
...HPV,?says Dr. Ferris. The type-specific assay, developed by Third Wave Technologies, Inc., in Madison, Wis., is being tested along with an assay that looks for the presence of 14 types of cancer-causing HPV. A test that detects 13 types of HPV already is commercially available, so the new test could become......omosomal map was created using mosquitoes that had developed in precisely controlled environmental rooms that allow the UO researchers to simulate climatic conditions occurring in nature anywhere in the world, from the tropics to the polar regions. The newly created map contains 900 million DNA base pairs. ...