Ebola virus: from wildlife to dogs
...h the animal virus reservoir and that some of them develop non-fatal infections. The presence of specific antibodies in the animals taken before the epidemics means that the Ebola virus has probably been circulating for a long time in Central African forests. The detection of such antibodies in other primate...Researchers test new therapy for advanced melanoma
... of medical microbiology and immunology who helped develop the technology used in the study. Electroporation is a technique in which a hand-held device applied to the skin delivers pulses of electricity to open up pores in the tumor cell membrane. This opening allows a small therapeutic molecule -- in this ...Disabling gene defuses rheumatoid arthritis in mice
...ation. Women are two to three times more likely to develop the disorder than men. Symptoms often occur in episodic bursts and may include morning stiffness, fatigue and joint and muscle pain. In severe cases, rheumatoid arthritis can damage cartilage, tendons, ligaments and bone, leading to joint deformity a...U. Iowa researchers improve Huntington's disease symptoms in mice
...a section of the human HD gene. These mice quickly develop movement and coordination abnormalities and they die young. Aggregates, or clumps of protein, also develop in certain brain cells. Davidson explained that this mouse is very good for proof-of-principle expe...Experiment station researchers to explore genome of disease-fighting fungus
...g the fungus, researchers say they will be able to develop new versions of the fungus to protect field crops from diseases. This would decrease the amount of pesticide and other chemicals applied throughout a growing season. "You also might be able to more effectively employ sustainable practices such as lo...Fungus Effective Against Winged Termites
...ers are currently seeking collaborators to further develop a formulation to deliver the fungal spores. They envision applying the fungus to buildings and trees already known to harbor termites before the swarms are in full swing. ARS is the U.S. Department of Agriculture's chief scientific research agency. ...Researchers Closer To Helping Hearing-Impaired Using Stem Cells
...ogether caused the marrow stromal cells to further develop into cells with many of the characteristics of auditory neurons, such as the presence of specific genes and proteins. Dr. Hashino said she and her colleagues are beginning new experiments to test the feasibility of marrow stromal cell transplantatio...Asymptomatic HIV babies could use earlier treatment
...ugs within two months of birth were less likely to develop AIDS by their third birthday than were infants who...bout 20 to 30 percent of HIV-infected infants will develop AIDS by around 4 months of age. The rest will not have advanced symptoms until they are about 6 year...Lipids get new comprehensive classification system
...lipids that occur with cellular metabolism, and to develop bioinformatics approaches that establish dynamic lipid networks. In order to coordinate their efforts with those of other groups, such as the Lipid Bank in Japan, the European Lipidomics Initiative, and the International Conference on the Biochemistr...Function of new cancer genes discovered
...th the very rare genetic condition cylindromatosis develop a lot of benign tumours on the skin. These tumours... cancer, Fanconi anaemia. People with this disease develop many highly malignant tumours at a young age, because the cell repair system is incapble of detachin...Second messenger NAADP shows fast, dose-related impact on satiety cycle
...ll levels of research, this approach has failed to develop a truly successful obesity drug to address this major global health problem. Enter a recently discovered and already controversial natural molecule called nicotinic acid adenine dinucleotide phosphate (NAADP), which is active in cells from plants to...Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines
The ability to select and develop compounds that act on specific cellular targets has just gained a computational ally ?a mathematical algorithm that predicts the precise effects a given compound will have on a cell’s molecular components or chemical processes. Using this tool, drug ...New vaccine means bye-bye to bacteria in the lung
...have cystic fibrosis. It is therefore important to develop a vaccine against this pathogen. Appearing online on 1 April 2005 in advance of print publication of the May issue of The Journal of Clinical Investigation, Ronald Crystal and colleagues from Cornell University use a novel strategy to create a geneti...Scientists map the world for nature conservation
...for an improved database that would enable them to develop more effective global nature conservation strategies. Botanists at the University of Bonn have now taken a major step in this direction with the publication, in the Journal of Biogeography, of a world map of plant biodiversity. The atlas is arranged...New understanding of cell movement may yield ways to brake cancer's spread
... exactly what triggers cellular migration can help develop treatments that halt cancer metastasis and immune disorders like arthritis and asthma. "Previous studies by us and others have identified how a migrating cell 'gets its wheels' and, mechanistically, is able to move. In this study, we have now determ...U of T researchers map role of Epstein-Barr virus in cancer
... shouldn't, which means they're now more likely to develop into cancer," Frappier says. "All viruses known to be able to cause cancer, like the human papillomavirus that causes cervical cancer for example, have been shown to work through this p53 protein, but up until now, no one's ever found any regulation...Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed
...age embryonic stem cells and allows these cells to develop symmetrically. In the absence of retinoic acid, the exterior of our bodies would develop asymmetrically, with the result being that our right side would be shorter than the left one. "On t...Cancer drug slows poxvirus in mice
...derstand the mechanisms of smallpox disease and to develop new and improved smallpox treatments and vaccines. NIAID is a component of the National Institutes of Health, an agency of the U.S. Department of Health and Human Services. NIAID supports basic and applied research to prevent, diagnose and treat inf...Genome study of beneficial microbe may help boost plant health
...new genomic data will help scientists more quickly develop new ways to boost the effectiveness of beneficial microbes in fighting plant diseases. "This genomic sequence reveals previously unknown traits of P. fluorescens that increase its potential for biological control," says Loper. She is a plant patholo...Immune system's distress signal tells bacteria when to strike back
... are "normal flora," people with no real infection develop a chronic disease. The battles between pathogens and their hosts have been going on for millions of years, Alverdy said, with each side constantly devising novel measures, countermeasures, and counter-countermeasures, including sophisticated mutual ...