SuperLigands - a database of ligand structures derived from the Protein Data Bank
...n treating patients. In addition, researchers must develop methods to efficiently direct the differentiation of embryonic stem cells to specific stable cell types. Scientists must also find a way to remove the remaining animal components from the laboratory procedures. Currently, the procedure for isolating ...Microscopes at microscopic size
...ine cellular conditions for certain diseases or to develop new treatments by studying the way cells react to ...amine biological samples. Our next step will be to develop simple, small diagnostic devices. Future generations may be able to use these as the basis for hand-...Important discovery about second most fatal cancer
...affected families have a genetic predisposition to develop DNA methylation. There is already evidence that su...cancer. Moreover, the colorectal cancers appear to develop in polyps that have been considered to be entirely harmless and have therefore been ignored up to no...Nature provides inspiration for important new adhesive
...like a mussel-protein adhesive. Then they began to develop other strong and water-resistant wood adhesives from renewable natural materials using mussel protein as a model. The research work has resulted in 11 papers in journals such as Macromolecular Rapid Communications and the Journal of Adhesion Science ...A new way to share models of biological systems
...s to address these issues." The first step was to develop a standard way of describing such models. The Systems Biology Markup Language (SBML), an open-source computer language developed by the SBML Team, is now widely accepted and is supported by over 75 different software systems worldwide. This allows co...Making Sure Sacred Sheep Don't Become Extinct
...to consider social implications," he explains. To develop the collection, animal physiologist Phil Purdy, also of the Fort Collins center, traveled to the Navajo Nation to collect germplasm from rams owned by several Navajo sheep producers. Until Purdy developed relationships with various breeders, there wa...Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage
...l of versatility, creating a variety of cells that develop in different ways to protect the body. To carry out these tasks, immune cells follow a career path that forks at various points in their development. In a report in the May 2005 issue of Immunity, Fox Chase Cancer Center scientists led by immunologis...Research into how prions act in the brain could hold the key to defeating diseases
...stroy. It is not known what causes the proteins to develop in this abnormal way and it is not known how they kill nerve cells in the brain. Professor Hugh Perry and colleagues of the University's School of Biological Sciences are examining exactly what makes particular nerve cells in the brain more susceptib...Where bacteria get their genes
...e virulent. "To maintain effective treatments and develop new antibiotics, it's important to monitor the rates and patterns of lateral gene transfer," said team member Howard Ochman, a UA professor of biochemistry and molecular biophysics and a member of UA's BIO5 Institute. The research also solves a long...NHGRI targets 12 more organisms for genome sequencing
...nimum set of genes that create a nervous system or develop a jaw, possibly illustrating how these systems have evolved in humans, and how they sometimes go wrong. Aplysia (Aplysia californica) is a sea slug that has been a very useful model in studying learning and memory in humans. Aplysia have very large ...Internet viruses help ecologists control invasive species
...whether some invaded systems have the potential to develop into invasion hubs. According to Muirhead and Mac... Lake Simcoe and Lake Kashagwigamog, are likely to develop as invasion hubs because most boaters and anglers leaving these lakes travel to lakes that are still...UCLA study assesses cost-effectiveness of Hepatitis B drugs
... all have varying risks and benefits. "We need to develop a more calculated approach and establish guideline...when reserved as a second-line agent in people who develop viral resistance for lamivudine ?a therapy that has been available for over 15 years. The study not...Insects, viruses could hold key for better human teamwork in disasters
...viruses typically take. The ideas the researchers develop will "augment current collaboration among first re...lly flawed," Contractor said. "Instead, we need to develop a strategy that leverages cutting-edge research in information technology to enable the rapid assemb...Next Generation Body Scanner Launched By The University Of Manchester
...look at the way brain tumours and cancers grow and develop and how different kinds of treatment might work. It will also help researchers looking into strokes and will enable them to understand the way the brain recovers in stroke patients. The scanner will also benefit researchers carrying out work int...Human Eggs Can Develop From Ovarian Surface Cells In Vitro
...h has shown for the first time that human eggs may develop directly from cultured ovarian surface epithelium ...gs. However, definitive proof that new oocytes may develop in adult human females will be if they can be found to differentiate in vitro from OSE cells derived...'EuroVacc 02' HIV Vaccine Trial Begins
...the United Kingdom. The goal of this network is to develop safe and effective preventive vaccines against HIV/AIDS. This group has been working together for more than five years, and has developed a pipeline of potential vaccines. The EuroVacc Foundation, a non profit organization, was created in 2002 as an...While on trail of dioxin, scientists pinpoint cancer target of green tea
...ical experts are already targeting in an effort to develop a new drug to stop the disease, scientists at the University of Rochester Medical Center have found. The research, which buttresses beliefs about the health benefits of green tea with solid scientific evidence, has been cited as part of the best doct......prehensive access to its GeneChip(R) technology to develop and market in vitro diagnostic tests for breast cancer, as well as an option to expand the agreement into other cancer areas. The agreement, made under the Powered by Affymetrix(TM) program, gives bioMerieux non-exclusive rights to Affymetrix' paten...Venom doc tracks down snake bioweapons
...al from other body tissues. This enabled snakes to develop more specific, highly potent toxins, ones that would cause their victims' bodies to turn against themselves upon injection. Over time, these newly derived toxins became a normal part of the saliva protein repertoire. To date, 24 different snake venom...DOE JGI launches IMG public online microbial genome data clearinghouse
...ges the IMG's data content and curation and helped develop the system, with additional support provided by DOE JGI's Microbial Ecology and Genome Data System groups. "The IMG system champions the principle of integration in an evolutionary context" said Kyrpides. "This is critical for enabling the generation...