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Tag: "develop" at biology news

Study of genomic DNA leads to new advances in cancer diagnostics

... being used to study drug-resistance mechanisms to develop new protocols and methods to treat cancer. Ultimately, the cellular changes that occur during cancer formation affect how the cell interacts with its microenvironment (ECM) and direct changes to the cytoskeleton and finally to the chromatin. Such ch...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...milar pathology as seen in human colon cancers and develop tumor growths called polyps in their colons, eventually leading to death. Inactivating the APC gene was found, as in human cells, to cause the accumulation of a protein called beta-catenin in the nuclei of these cells. Kaestner's group had earlier p...

New methods of gene delivery using lasers

...ght to enhance our understanding of biology and to develop new biomedical devices. Although other research groups have touched on this area, the St Andrews group have greatly simplified the technique by using an extremely simple and versatile miniature violet laser which is compatible with standard microscop...

Influenza vaccine uses insect cells to speed development

...itional egg-based method requires 3 to 6 months to develop the vaccine. With our cell-based method, the time from receipt of the virus strain to the final vaccine product would be shortened to approximately 1 to 2 months." Today's flu vaccines are prepared in fertilized chicken eggs. The eggshell is punctur...

RNA project to create language for scientists worldwide

... knowledge has created the need for researchers to develop a shared vocabulary and system for describing, cat...been formed to do just that. "The consortium will develop a common vocabulary and scientific concepts relating RNA structure and function to allow RNA scienti...

South America's vast pantanal wetland may become next everglades, UNU experts warn

...ate change and biodiversity ?underline the need to develop inter-linkages at the policy level as well, UNU says. In other words, the environmental, economic, and social impacts of activities of stakeholders in the Pantanal should be considered in managing the wetlands. It says improved coordination at the r...

Scientists solve structure of key protein in innate immune response

...d by LPS. "Pharmaceutical companies have tried to develop anti-septic shock agents for a long time without clear success," explains Dr. Lee. "Since LPS is an important inducer of septic shock, blocking LPS receptors such as CD14 are among the most important targets. Our structure shows the shape of the LPS ...

Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals

...s. "For 20 years it has been the chemist's job to develop agents that can be used to enhance MRI contrast," said Eric Ahrens, assistant professor of biological sciences in the Mellon College of Science at Carnegie Mellon. "Now, with our approach, we have put this job into the hands of the molecular biologis...

Affymetrix and Stratagene Announce Strategic Software Alliance

...alysis. As part of this agreement, Stratagene will develop a new software package for Affymetrix, ArrayAssist(R) Lite, which will be offered as a standard statistical analysis solution of Affymetrix gene expression microarrays. In April 2005, Affymetrix will make ArrayAssist Lite available to its existing G...

Chemists identify key gene in development of type 1 diabetes

...that lacked the gene for the MIF protein failed to develop diabetes compared to mice that possessed the gene,...ps a lifetime. But such a drug would take years to develop and test, the researchers caution. Likewise, effective gene therapy against the disease may take man...

Towards precise classification of cancers based on robust gene functional expression profiles

...that lacked the gene for the MIF protein failed to develop diabetes compared to mice that possessed the gene,...ps a lifetime. But such a drug would take years to develop and test, the researchers caution. Likewise, effective gene therapy against the disease may take man...

New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines

...B cells to adaptive B cells. Alternatively, we can develop ways to induce that first line of polyspecific antibody defense during vaccination, if these antibodies are not harmful to those being vaccinated," Haynes said. "We now have a window into how to study HIV vaccines from the host side of the problem,"...

Antibiotic might fight HIV-induced neurological problems

...rain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body. Five monkeys infected with simian immunodeficiency virus (SIV), a very close relative of HIV, and treated with minocycline had less damage to brain cells, less brain inflam...

Protein offers way to stop microscopic parasites in their tracks

...ity have identified a protein that could help them develop drugs to stop or slow cell invasion by malaria and other parasites known as apicomplexans. Results of the study will appear in the March 15 issue of Proceedings of the National Academy of Sciences. Scientists identified the new protein in the protoz...

Asthma gene clusters identified

...espond to treatment, we will eventually be able to develop customized therapy for patients with different gene expression profiles," she said. ...

Mayo Clinic Researchers Create 'Obedient Virus'; First Step To Use Measles Virus Against Cancer

...cancer cells and non-cancer cells, so we wanted to develop a method whereby we could retarget the virus to infect cancer cells only," says Dr. Russell. "And we succeeded." ...

Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy

...ing single variables in parallel we believe we can develop effective cancer vaccines in a much shorter time than the conventional approach of trying variables sequentially." The CVC has clinical research sites in Australia, Belgium, Germany, Japan, Switzerland, the UK and the USA. ...

Multiple Campylobacter Genomes Sequenced

...ually. Diarrhea, cramps, abdominal pain, and fever develop within 2? days of picking up a pathogenic Campylob...ction can sometimes be fatal, and some individuals develop Guillain-Barré syndrome, in which the nerves that join the spinal cord and brain to the rest of the ...

Potential treatments for neurofibromatosis

...ieve will starve the tumors. "It's much easier to develop targets against a non-malignant cell than it is th... appear in adolescence or adulthood. A patient may develop hundreds of neurofibromas over a lifetime. Some NF 1 patients also develop numerous light brown (ca...

Surprising findings reported about iron overload

.../ethnic groups who were screened. Individuals who develop hemochromatosis/iron overload absorb an excessive ... discovered, or that they do not, for some reason, develop hemochromatosis/iron overload despite their high blood levels of iron." He said that the NEJM paper...

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