Computers to be used to find blueprint for new influenza drug
...a project that could help pharmaceutical companies develop a better drug that could be taken by people coming down with flu to stop the disease developing. The drug would work by being chemically very similar to part of the protective coating around the cells in our throats that the flu virus first attacks ...U-M scientist to talk about tissue engineering at AAAS
...d the next step would be working with engineers to develop anatomically correct scaffolding with the same cur...ntours of natural bones. That would help a patient develop new bone almost indistinguishable from nature's original equipment. Many researchers at University ...Live Recombinant Adenovirus Vaccine Technique Explored
...berg School of Public Health are exploring ways to develop new vaccines for a variety of illnesses using gene...pecifically, Dr. Ketner and his colleagues hope to develop a vaccine for human papillomavirus (HPV) that could be used in the developing world. HPV causes 500,...Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
... Gilmore.“Secondly, this discovery will help us to develop new ways to treatinfections that are resistant to antibiotics, making them less severe.Based on an understanding of how this toxin system works, we hope todevelop toxin inhibitors,?says Gilmore.The third area of interest is currently science fiction,...Molecular machine may lead to new drugs to combat human diseases
...formation gleaned from this study in an attempt to develop new drugs, Golden said. Introns were unknown until the late 1970s, and scientists are still investigating their function. Crystallization of the complex is one tool to determine their purpose. Two intron structures in different stages of the cycle ...Novel Therapy Tested in Mice Could Chase Away Cat Allergies
...rovide proof-of-concept for using this approach to develop therapies to prevent deadly food allergy reactions...He also is interested in applying this approach to develop a preventive treatment for serious food allergies. ...Color-blind method opens new doors in DNA sequencing
...he light into colors." Metzker is also seeking to develop a chip-based imager than could be used in his overall project on sequencing-by-synthesis (SBS), which is funded by the National Human Genome Research Institute. SBS could lead to the ability to sequence an individual's own genome rapidly and inexpens...Mouse brain tumors mimic those in human genetic disorder
...ctually be diagnostically informative. "Thesemice develop brain tumors with many of the same features as those seenin children with NF1, and studying those tumors has helped usunderstand the cellular events involved in NF1 brain tumordevelopment," says principal investigator David H. Gutmann, M.D.,Ph.D., th...Essential mangrove forest threatened by cryptic ecological degradation
... of other rivers. Whereas these projects certainly develop the ability to grow crops inland, at the same time such practices drastically affect the coastal zone by introducing an excess of fresh water. The consequences range from adverse shifts in the composition of mangrove tree species to disrupted ethnobi...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
...which apparently work in concert to control how we develop in the womb. Instead of being activated individually like most genes, the HOX genes appear to be turned on in groups by massive numbers of tags. HOX genes also are deeply involved in cancer, making the findings particularly important. Some of the pr...First 'atlas' of key brain genes could speed research on cancer, neurological diseases
...ent parts of the braindevelop ?and, in some cases, develop abnormally or malfunction.The scientists say the map will accelerate research on brain tumors andneurological diseases that result from mutations in these switch genes?called “transcription factors.?When these genes are altered, thegenes they control...U-M scientists find genes that control growth of common skin cancer
...particularlyimportant given the current efforts to develop Hh pathway inhibitors asa means of combating human BCCs, as well as other cancers. In contrastto other cancer models where inhibition of Hh signaling leads todurable tumor regression, Dlugosz's new work raises the possibilitythat Hh pathway inhibitio...Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
...6 online by the EMBO Journal, could helpscientists develop a vaccine that is significantly more effective atp...ure of this important proteinmeans we can begin to develop a vaccine that is more effective inchildren than those that are currently available,?Kriwacki said.E...New comparative toxicogenomics database
...6 online by the EMBO Journal, could helpscientists develop a vaccine that is significantly more effective atp...ure of this important proteinmeans we can begin to develop a vaccine that is more effective inchildren than those that are currently available,?Kriwacki said.E...Elephants imitate truck noises, other animals
...n communication system in which animals and humans develop new signals with shared associations. Recent playb...ots, bats, and dolphins, may use vocal learning to develop new communication signals for maintaining complex individual-specific social relationships, study co...UCSD researchers maintain stem cells without contaminated animal feeder layers
...titute, said that "it will be rather simple now to develop a specific defined medium that allows for the maintenance of the human stem cells and enhances research without the problem of contaminating animal cells and their products." In a summary to their paper, the researchers noted that "the identificatio...Nanogen Issued Patent for Electronic Microarray With Memory
...tual property portfolio illustrates our ability to develop differentiated advanced diagnostic products that a...ay and broad suite of analyte specific reagents to develop tests to detect infectious diseases, drug toxicity and mutations associated with cancer, cardiovascu...Researchers discover molecule that causes secondary stroke
...percent of patients who survive the initial stroke develop vasospasm, and 40 percent of them die from it. Vasospasm, says neurology department researcher Joseph Clark, PhD, results from a buildup of toxins caused by bleeding from the initial stroke. "Normally the cerebral spinal fluid that envelopes the bra...Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
...eered toover-express HER2/neu. These mice normally develop breast cancer in allten of their mammary glands by the time there are 120 days old. In thisexperiment, they vaccinated the mice three times with VRP-neu, and “nota single mouse developed a tumor,?says Lachman.Lachman suggests the vaccine might prove ......n communication system in which animals and humans develop new signals with shared associations. Recent playb...ots, bats, and dolphins, may use vocal learning to develop new communication signals for maintaining complex individual-specific social relationships, study co...