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Tag: "develop" at biology news

Enzyme's newly discovered role may make it target for arthritis treatment

...in G and other closely related proteases failed to develop arthritis after the injections. This led them to look for the mechanisms by which these proteases regulate inflammation. Observations made by Pham's lab and other groups had linked the earliest stages of inflammation in the animal models to neutroph...

Study finds adult stem cells can replicate

...in G and other closely related proteases failed to develop arthritis after the injections. This led them to look for the mechanisms by which these proteases regulate inflammation. Observations made by Pham's lab and other groups had linked the earliest stages of inflammation in the animal models to neutroph...

Fragile US vaccine system needs improvement despite dramatic gains in health over past century

...n. The most recent estimates (2000) of the cost to develop a new vaccine range from $110 million to $802 million, and five vaccines recently reviewed by the National Vaccine Advisory Committee took from two to twenty-one years from Phase I clinical trials to licensing. Safety concerns, such as the problem w...

Researchers make headway in mystery of migraines

...s that cause disease is important, but in order to develop treatments we must understand what these mutations do." By engineering several genetic mutations known to cause inherited migraines (type 2), and incorporating them into human cells, Dr. Blostein and her team showed several genotypes damage the opera...

UI researcher studies deafness in fruit flies, humans

...t fruit flies and humans rely on the same genes to develop their auditory organs, which in the fruit fly is in the antenna. Eberl's research shows that at least one molecular component specialized for hearing function, myosin VIIA, is conserved in these ears. In looking for clues to inherited deafness in hu...

Stem cell therapy successfully treats heart attack in animals

...ected until mid-2006. "Ultimately, the goal is to develop a widely applicable treatment to repair and revers...adult stem cells do not have the same potential to develop into different organ tissues, as do embryonic stem cells, whose use is more controversial. ...

Combination therapy leads to partial recovery from spinal cord injury in rats

...nal cords of embryonic rats. These precursor cells develop from stem cells and are specialized so that they c...DNF help myelin-producing cells (oligodendrocytes) develop and survive. Dr. Whittemore and his colleagues injected the treated precursor cells into the spinal...

Proteomics brings researchers closer to understanding microbes that produce acid mine drainage

...rried out by the DOE Genomics:GTL Program that can develop novel approaches and solutions to national challenges." Banfield is continuing her studies of the Richmond Mine biofilm and acid producing biofilms elsewhere, which includes work with the Joint Genome Institute to obtain more genomes of community me...

Diabetic nerve therapy shows 'striking' results

...ed 50 per cent of patients with long-term diabetes develop some form of neuropathy that can cause numbness and sometimes pain and weakness in the hands, arms, feet and legs. Currently, patients are treated with painkillers and antidepressants that do not treat the underlying nerve damage. Progression to amp...

Where Bacteria Get Their Genes

...e virulent. "To maintain effective treatments and develop new antibiotics, it's important to monitor the rates and patterns of lateral gene transfer," said team member Howard Ochman, a UA professor of biochemistry and molecular biophysics and a member of UA's BIO5 Institute. The research also solves a long...

Study Finds Moderate Hypothermia A Safe Treatment For Traumatic Brain Injury In Kids

...mechanisms following an injury and also be able to develop other more effective treatments." Lowering body temperature can help control brain swelling and intracranial pressure, which can also exacerbate secondary injury if left unchecked. Induced hypothermia can be accomplished using several methods. Surfa...

Specialized immune-system B cells play double-barreled role

...igned simply empirically," he said. "The designers develop a formulation that's a best guess and test it on patients or animal models to determine its effectiveness. But now, research is reaching a point where we can understand the signals that switch certain B cell populations on and off and regulate their ...

Researchers grow stem cells from human skin

...The promise of stem cells lies in their ability to develop into specialized types of cells and to replicate themselves. Scientists hope to harness the potential of stem cells and use them to replace damaged cells and tissue in conditions such as spinal cord injuries, diabetes, Alzheimer's disease, stroke and...

Scientists reveal how disease bacterium survives inside immune system cell

...d similar studies, he adds, could help researchers develop therapeutics to treat or prevent bacterial infections. ...

Genetic links could unlock clues to leading cause of blindness

... of the disease, and millions more are expected to develop it within the next 15 years. The disease causes nodule-like specks to build up in the eye, chipping away central vision over time. But Dawson said most people don't even realize something is wrong until they detect changes in their vision. The disea...

ORNL, UC Berkeley unravel real-world clues to Earth's mysteries

...the DOE Genomics: Genomes to Life program that can develop novel approaches and solutions to national challenges." Hettich said their results would not have been possible without the collaboration with UC Berkeley, where Jill Banfield is an expert in natural microbial communities. Banfield, a professor in t...

Montreal researchers probe the genetic basis of memory

...f the role of GCN2 in long-term memory may help us develop targeted drugs designed to enhance memory in patients with memory loss due to illnesses such as Alzheimer's disease, where protein synthesis and memory are impaired," concludes Dr. Karim Nader. ...

First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology

...esents a considerable advance over past efforts to develop avian transgenes, which were limited to the insertion of only small pieces of DNA," commented Dr. Etches. "The technology described here is a general method for inserting DNA encoding proteins of essentially any size and complexity while achieving hi...

Researcher gets NSF grant to create mutant maize lines

... in his Cornell lab. Brutnell and colleagues will develop lines of maize that have a piece of DNA that can be moved from one part of the plant's genetic sequence, or genome, to another. Called transposons, or jumping genes, these mobile pieces of DNA knock out the function of genes they jump into, thereby m...

Scientists succeed in cloning human embryos from eggs matured in the lab

... embryonic stem cell lines from cloned embryos and develop them to provide eggs and sperm for infertile coupl...he six- to ten-cell stage. One embryo continued to develop to the compacted stage, when the individual cells started to flatten and increase their contact with...

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